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TUHH > Forschung und Transfer > Forschungsorganisation > FSP Medical Technology & Biomechanics

FSP Medical Technology & Biomechanics

Spokesperson: Prof. Alexander Schlaefer, schlaefer(at)tuhh.de

Deputy Spokesperson: Prof. Moritz Göldner, moritz.goeldner(at)tuhh.de

Modern patient care is unthinkable without the continuous improvement of implants and diagnostic procedures over the last 50 years. Diseases can now be detected much earlier and treated better. Future improvements require joint efforts of all engineering disciplines together with the medical specialties. Modern imaging techniques in combination with machine learning methods as well as the improvement of surgical procedures play an important role in this context. Digitization in combination with classical electrotechnical, mechanical and biotechnological approaches is the way of the future to solve health problems of an aging society.

The TUHH covers the current topics in medical technology both in basic research and in applied research. The close research cooperation with the University Medical Center Hamburg-Eppendorf (UKE) under the umbrella of the joint Medical Technology Research Center (FMTHH) provides the ideal conditions for this. New methods and procedures developed at the TUHH can thus be tested and further developed in a clinical environment. Young scientists from the fields of engineering and medicine thus learn to work together in joint projects at an early stage.

The focus of research in the FSP is on

Imaging methods (Institute for Biomedical Imaging),
Robotics, navigation, and machine learning methods (Institute of Medical Technology and Intelligent Systems),
Microelectronic sensors, implants and organ-on-chip (Institute of Microsystems Engineering),
Human-machine interfaces (Institute of Integrated Circuits),
Endoprosthesis, implants and biomechanics (Institute of Biomechanics),
3D tissue models and tissue engineering (Institute of Bioprocess and Biosystems Engineering and Institute of Continuum and Materials Mechanics),
Customizable simulation models e.g. for replicating the patient-specific blood circulation system using additive manufacturing techniques (Product Development and Design Engineering).

In addition to carrying out numerous DFG and BMBF projects, the Interdisciplinary Competence Center for Interface Research (ICCIR) investigates and optimizes the properties and interactions of materials and tissues at interfaces. Intelligent medical implants based on optoelectronic components for new human-machine interfaces are being researched in the I3-Lab HELIOS. The I3-Lab M4 focuses on the modeling of soft tissue by machine learning methods. In addition to these basic research-oriented projects, there is close cooperation with local, national and international medical technology companies (including B. Braun Aesculap, DePuy Synthes, Philips, Essity). Continuing education of physicians together with the relevant professional associations enables the transfer of the latest findings directly into application

An independent master's degree program in medical engineering with 3 specializations covers the entire breadth of the research field. In the master's degree programs of all deaneries, specializations from medical engineering can be taken.

Research Field

Cyber Physical & Medical Systems

Institutes

Name	Institute
Prof. Dr. Sara Checa Esteban	Biomechanics
Prof. Christian Cyron	Continuum and Material Mechanics
Prof. Dr.-Ing. Alexander Düster	Ship Structural Design and Analysis
Prof. Dr. Moritz Göldner	Data-Driven Innovation
Prof. Dr. Anna-Lena Heins	Bioprocess and Biosystems Engineering
Prof. Dr. Cornelius Herstatt	Technology and Innovation Management
Dr.-Ing. Marko Hoffmann	Multiphase Flows
Dr.-Ing. Gerd Huber	Biomechanics
Prof. Dr.-Ing. Thomas A. Kern	Mechatronics in Mechanics
Prof. Dr. Maximilian Kiener	Ethics in Technology
Prof. Dr.-Ing. Tobias Knopp	Biomedical Imaging
Prof. Dr.Ing. Alexander Kölpin	High-Frequency Technology
Prof. Dr.-Ing. Dieter Krause	Product Development and Mechanical Engineering Design
Prof. Wolfgang Krautschneider	Integrated Circuits
Prof. Dr.-Ing. Ulf Kulau	Smart Sensors
Sarah Latus	Medical Technology and Intelligent Systems
Prof. Dr. Marko Lindner	Mathematics
Prof. Michael Morlock	Biomechanics
Prof. Dr.-Ing. Ralf Pörtner	Bioprocess and Biosystems Engineering
Prof. Dr.-Ing. Thomas Rung	Fluid Dynamics and Ship Theory
Prof. Dr.-Ing. Alexander Schlaefer	Medical Technology and Intelligent Systems
Prof. Dr.-Ing. Michael Schlüter	Multiphase Flows
Prof. Dr. Christian Schuster	Theoretical Electrical Engineering
Prof. Dr.-Ing. Hoc Khiem Trieu	Microsystems Technology
Dr. Cheng Yang	Theoretical Electrical Engineering

Current Projects (Highlights)

Institute	Projects
Biomechanics	Process and Implant Improvement to reduce Periprosthetic Femur Fractures in Total Hip Arthroplasty Analysis and Registry data of the German Arthroplasty Register EPRD Process and Design Modifications to improve Primary Stability of Acetabular Cups in Total Hip Arthroplasty
Biomedical Imaging	Adaptive Crossmodale Sensordatenerfassung Erstes Niedrigfeld Magnetic-Particle-Imaging System für humane Neurologische Anwendungen MAGnetic Particle Imaging for the Treatment and Imaging of Stroke
Bioprocess and Biosystems Engineering	Digital Twin-gestütztes Prozessdesign für NK-Zelltherapien
Continuum and Material Mechanics	Computersimulation des menschlichen Magens Computersimulation der Biokorrosion und Festigkeit biodegradabler Mg-Knochenimplantate Analyse der mechanischen Eigenschaften von Weichgewebe mit Hilfe von maschinellem Lernen
Data-Driven Innovation
Ethics in Technology
Fluid Dynamics and Ship Theory	Analyse der Strahlausbreitung und Schallemissionen von Schiffmanövrierorganen durch Simulation Development of a novel wave energy converter based on hydrodynamic lift forces Echtzeit-nahe Modellierung und Simulation von Umwelteinflüssen auf den Energieverbrauch von Schiffen
High-Frequency Technology	SFB 1483: Teilprojekt Kardiovaskuläres respiratorisches Mikrowelleninterferometer Systementwurf und Signalanalyse eines Interferometers zur radargestützten Epilepsiediagnostik Remote Haptics
Integrated Circuits	Entwicklung eines neuartigen CMOS-Sensorarrays sowie einer miniaturisierten On-Chip-Ausleseelektronik mit NFC-Datenübermittlungselektronik, drahtloser Energieversorgung und direkt integriertem Mikrocontroller Entwicklung eines Sensor-Mikrochips mit dreidimensionaler Messung von Kräften, Momenten und deren Richtung eines Kalibrierungssystems zur Anwendung im Systemverband Innovative Technologien in der Krebsdiagnostik und -therapie
Mathematics	Modellierung, Simulation und Optimierung mit fluiddynamischen Anwendungen Positional Games und deren Zusammenspiel mit der Theorie von Zufallsgraphen TIME parallelisation: for eXascale computing and beyond
Mechatronics in Mechanics	Gleichstromenergieversorgung für Schiffe: Konzepterstellung und Optimierung der Energieverteilung sowie Sektorenkopplung auf Schiffen unter Berücksichtigung dezentraler Energieerzeugung und Verteilung auf DC
Medical Technology and Intelligent Systems	Vollautomatische, deep-learning basierte Detektion von Anomalien auf Schädel-MRT-Bilddaten für die Patientenversorgung (AnomalieDetektor); Entwicklung von Deep-Learning (DL) Architekturen zur Anomalie-Detektion Vollautomatische, strukturierte Befundung von Röntgen-Thorax-Aufnahmen für die Routineanwendung in der Patientenversorgung Digitalisierung postmortaler Biopsien (LOM)
Microsystems Technology
Multiphase Flows	Aerosolpartikel und ihre Ausbreitung - Wissenschaftliches Netzwerk zur Unterstützung des interdisziplinären Austausches in der DFG-Fokusförderung COVID-19 Feinblasen für biokatalytische Prozesse: Mikroskalige Phänomene und neuartige Anwendungen Mass Transfer and Hydrodynamics in Multiphase Reactors
Product Development and Mechanical Engineering Design
Ship Structural Design and Analysis	Echtzeitprognose der Bewegung von Offshore-Strukturen im Seegang; Nichtlineare Prognose von Seegang und Strukturbewegung, Wellenableitung und Implementierung Einfluss korrosiver Medien auf die Schwingfestigkeit von Offshore Windenergieanlagen Entwicklung eines Entwurfskonzepts für Personenzüge und Kreuzfahrtschiffe unter Berücksichtigung von automatisierter Fertigung
Smart Sensors	Wireless Communication Network
Technology and Innovation Management
Theoretical Electrical Engineering	Hochauflösende Vollwellenmodellierung von Gehirnimplantatsystemen: vom IC bis zum menschlichen Körper Wechselwirkung des elektromagnetischen Nahfeldfeldes und des menschlichen Körpers: von der Theorie zur Realität Vorhersage der Feldexposition von elektronischen Geräten im, am und außerhalb des Körpers mit Ungewissheit und Variabilität

Cooperations (Highlights)

Institut für Biomechanik

Kooperation mit Unternehmen

DePuy Synthes
Link
Essity
Peter Brehm

Kooperation mit Kliniken

Institut für Rechtsmedizin, Universitätsklinikum Hamburg-Eppendorf
Klinik und Poliklinik für Unfallchirurgie und Orthopädie, Universitätsklinikum Hamburg-Eppendorf
Department of Oral and Maxillofacial Surgery, Charité Universitätsmedizin Berlin
Centrum für Muskuloskeletale Chirurgie, Charité Universitätsmedizin Berlin
Klinik für Unfallchirurgie, Orthopädie und Plastische Chirurgie, Universitätsmedizin Göttingen
Orthopaedic Surgery Imperial College London

Institut für Medizintechnische und Intelligente Systeme

Kooperation mit Unternehmen

Philips GmbH Innovative Technologies/ Research Laboratories Hamburg
jung diagnostics GmbH
eemagine Medical Solutions GmbH
WEINMANN Emergency Medical Technology GmbH + Co. KG

Kooperation mit Kliniken

Institut für Osteologie und Biomechanik (IOBM), Universitätsklinikum Hamburg-Eppendorf
Institut für Rechtsmedizin, Universitätsklinikum Hamburg-Eppendorf
Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde, Kopf- und Halschirurgie, Universitätsklinikum Hamburg-Eppendorf
Universitätsklinikum Schleswig-Holstein, Campus Lübeck
Universitätsklinikum Schleswig-Holstein, Campus Kiel

Publications (Highlights)

Institute	Paper
Biomechanics	T. Konow, P.J. Schlieker, F. Lampe, B. Ondruschka, M. Morlock, G. Huber. "Influence of Bone Morphology and Femur Preparation Method on the Primary Stability of Hip Revision Stems", 2022 Journal of Orthopaedic Research P. Krull, A. Steinbrück, A.W. Grimberg, O. Melsheimer, M. Morlock, C. Perka. " Modified acetabular component liner designs are not superior to standard liners at reducing the risk of revision: an analysis of 151,096 cementless total hip arthroplasties from the German Arthroplasty Registry, 2022 Bone Joint Journal 104-B, 801-810 M. Morlock, E. Gomez-Barrena, D.C. Wirtz, A. Hart, J.P. Kretzer. "Explant analysis and implant registries are both needed to further improve patient safety", 2022 EFORT Open Reviews 7, 344-348
Biomedical Imaging
Bioprocess and Biosystems Engineering	J. Möller, R. Pörtner "Digital Twins for tissue culture techniques - concepts, expectations and state of the art", 2021 MDPI Processes K.B. Kuchemüller, R. Pörtner, J. Möller. "Digital Twins and Their Role in Model-Assisted Design of Experiments, 2021 Advances in biochemical engineering/biotechnology 177: 29-61 E. Fattahi, S. Taheri, A.F. Schilling, T. Becker, R. Pörtner. "Generation and evaluation of input values for computational analysis of transport processes within tissue cultures", 2022 English Life Science 22: 681-698
Continuum and Material Mechanics	S. Brandstaeter, A. Gizzi, S.L. Fuchs, A.M. Gebauer, R.C. Aydin, C.J. Cyron. "Computational model of gastric motility with active-strain electromechanics", 2018 Wiley Online Library A. Hermann, A. Shojaei, D. Steglich, D. Höche, B. Zeller-Plumhoff, C.J. Cyron. "Combining peridynamic and finite element simulations to capture the corrosion of degradable bone implants and to predict their residual strength", 2020 Elsevier K. Linka, C. Cavinato, J.D. Humphrey, C.J. Cyron. "Predicting and understanding arterial elasticity from key microstructural features by bidirectional deep learning", 2022 Elsevier
Data-Driven Innovation	M. Goeldner, J. Hagen. " How to identify and support innovative patients? Evidence on user innovation in healthcare from a large-scale study in Germany", 2022 19th International Open and User Innovation Conference, Zürich, Switzerland M. Goeldner. " Patients and Caregivers as Developers of Medical Devices - An Empirical Study on User Innovation in the Healthcare Sector, 2021 Springer Wiesbaden M. Goeldner, C. Herstatt, F. Tietze. "The emergence of care robotics - A patent and publication analysis, 2015 Technological Forecasting and Social Change, 92, 115 - 131
Ethics in Technology
Fluid Dynamics and Ship Theory
High-Frequency Technology	Automated non-contact respiratory rate monitoring of neonates based on synchronous evaluation of a 3D time-of-flight camera and a microwave interferometric radar sensor Contactless analysis of heart rate variability during cold pressor test using radar interferometry and bidirectional LSTM networks Continuous In-Bed Monitoring of Vital Signs Using a Multi Radar Setup for Freely Moving Patients
Integrated Circuits
Mathematics	D.Dahl, Ö. Yildiz, E. Frick, C. Seifert, M. Lindner, C. Schuster. " Feasibility of uncertainty quantification for power distribution network modeling using PCE and a contour integral method, 2018 IEEE International Symposium on Electromagnetic Compatibility J. Dornemann, N. Rückert, K. Fischer, A. Taraz. " Artificial Intelligence and operations research in maritime logistics", 2020 Hamburg International Conference of Logistics (HICL) 30: 337-381 R. Ahrens, Z. Lakdawala, A. Voigt, V. Wiedemeyer, V. John, S. Le Borne, K. Sundmacher. "Numerical methods for coupled population balance systems applied to the dynamical simulation of crystallization processes
Mechatronics in Mechanics
Medical Technology and Intelligent Systems
Microsystems Technology
Multiphase Flows
Product Development and Mechanical Engineering Design
Ship Structural Design and Analysis
Smart Sensors	M. Drobczyk, A. Lübken, C.Strowik, U.-V. Albrecht, J. Rust, J. Beringer, U. Kulau. "A Wireless Communication Network with a Ballistocardiography Experiment on the ISS: Scenario, Components and Pre-Flight Demonstration", 2022 IEEE Journal of Radio Frequency Identification U. Kulau, J. Rust, D. Szafranski, M. Drobczyk, U.-V. Albrecht. "Differential BCG Sensor System for Long Term Health Monitoring Experiment on the ISS", 2022 International Conference on Distributed Computing in Sensor Systems (DCOSS) T. Clausen, T. Jura, N. Jäne-Raden, M. C. Wolf, L. Wolf, U. Kulau. "A Precise, Parallel and Scalable Measurement System for Ballistocardiographic Research". 2021 Smart Health 19
Technology and Innovation Management
Theoretical Electrical Engineering	Esmaeili, Hamideh, Cheng Yang, and Christian Schuster. "Flexible Numerical Evaluation of Human Head Exposure to a Transmitter Coil for Wireless Power Transfer at 13.56 MHz." 2022 International Symposium on Electromagnetic Compatibility–EMC Europe. IEEE, 2022' Yang, Cheng, Morten Schierholz, Eileen Trunczik, Leon Maximilian Helmich, Heinz-D. Brüns, and Christian Schuster. "Efficient and Flexible Huygens’ Source Replacement of mm-scale Human Brain Implants." In 2021 IEEE International Joint EMC/SI/PI and EMC Europe Symposium. IEEE, 2021.