Former Employees

Former Administrative Staff
  • Jeanette Felsberg

  • Cornelia Heinz

  • Jutta Hülsmann

  • Alexandra Kalski

  • Madeleine Otto

  • Heike Wessling

Former Post Doctorates

Former Doctoral Researchers

Daniel Bezecny

Dipl.-Phys. Daniel Bezecny

2012 - 2019        Research Fellow at the IMS

Research Expertise


Melanie Bothe

Dipl.-Ing. Melanie Bothe

2011 - 2014        Research Fellow at the IMS

Research Expertise

  • Experimental analysis of local mass transfer phenomena in bubble columns using optical measurement techniques

  • Validation of simulations based on Direct Numerical Simulation (DNS) and Computer Fluid Dynamics (CFD)


Christian Busch

Christian Busch, M.Sc.

2017 - 2018        Research Fellow at the IMS

Research Expertise

  • Liquid/liquid and liquid/gas jet-loop-reactors

  • Liquid/gas trickle-bed-reactors

  • Characterization of a jet stream via Particle Imaging Velocimetry (PIV)


Raffaele Colombi

Raffaele Colombi, M.Sc.

2018 - 2022        Research Fellow at the IMS

Research Expertise


Jürgen Fitschen

Dr.-Ing. Jürgen Fitschen

2018 - 2023        Research Fellow at the IMS

Boehringer Ingelheim Pharma GmbH & Co. KG
Bioprocess Development Biologicals

Binger Strasse 173

55216 Ingelheim am Rhein

Phone +49 7351 54-177970

Mail Dr. Jürgen Fitschen

Research Expertise

  • Large Scale Bioreactors

  • Characterization of Heterogeneities in Aerated Stirred Tank Reactors

  • Characterization of Mixing Time


Tobias Freund

Tobias Freund, M.Sc.

2021 - 2022        Research Fellow at the IMS

Research Expertise

CFD Simulation of non-Newtonian fluids


Torben Frey

Torben Frey, M.Sc.

2019 - 2023        Research Fellow at the IMS

Research Expertise

Simulation and Modeling of Static Mixers within the framework of KoPPonA 2.0


Research

Continuous Polymerization in Modular, Intelligent Reactors Resistant to the Formation of Deposits (KoPPonA 2.0)

The main objective of the ENPRO 2.0 initiative is to increase energy efficiency of new production processes. A number of energy demanding and inefficient processes are allocated within the German chemical industry, especially the production of pharmaceutical, fine and special chemicals. The concerned products are mostly produced utilizing multi-product plants and small batch processes due to small throughput. During the first phase of the ENPRO 1.0 initiative (2014-2017) the project partners have developed flexible, scalable and modular plant concepts. Micro-structured devices have been proven to suit requirements for the combined product and process development. However, one drawback of micro-structured mixers, reactors and heat exchangers for continuous processes is the formation of gel or solid particles leading to fouling and blocking of the device.

The KoPPonA 2.0 project drives the development of continuous process concepts for polymer production which are sensitive to fouling. A conglomerate of plant operators, equipment and sensor suppliers, material scientists and process engineers work together in KoPPonA 2.0 to research causes and preventive measures of fouling. KoPPonA 2.0 uses innovative approaches in plant design, surface modification, and reaction control are used to allow efficient and safe operation of continuous polymerization processes. By investigating basic fouling mechanisms in continuous polymerization processes a universal comprehension of fouling is to be derived.

The Institute of Multiphase Flows (V-5) generates a comprehensive computational fluid dynamics (CFD) model of the process components that are prone to fouling. The model incorporates hydrodynamic flow phenomena, mass transfer, kinetics and different fouling mechanisms. The models are validated by means of Confocal Laser Scanning Microscopy (CLSM) to visualize three-dimensional concentration distribution at micro scale (resolution down to 1 μm) with Laser-Induced Fluorescence (LIF). Furthermore, reactive models are validated by means of the novel imaging UV/Vis spectroscopy developed at the IMS.

Education

Graduate Teaching Assistant

  • Process Design Course WiSe 19/20

  • Computional Fluid Dynamics in Process Engineering SoSe 20, SoSe 21, SoSe 22, and SoSe 23

  • Lagrangian Transport in Turbulent Flows SoSe 20 and SoSe 21

  • Turbulent Flows SoSe 22 and SoSe 23

Supervised Theses

  • "Education 4.0: Development of an Extended Reality Tool for CFD-aided Design and Development of a Shell-Tube Heat Exchanger (working title)", Jeswin Kannampuzha Francis, Master thesis, ongoing

  • "Experimentelle Bestimmung der Löslichkeit von Stickstoffmonixid in Methanol mithilfe einer chemischen Reaktion", Xuan My Le, Project thesis, 2023

  • "Experimentelle Untersuchung der laminaren Mikrovermischung in einem Kaskadenmischer durch konfokale LIF-Messung einer reaktiven Strömung", Anna-Christin Menzel, Master thesis, 2023

  • "Analysis of Transport Barriers in Continuous Mixers by means of Lagrangian Coherent Structures", Christoph Wigger, Master thesis, 2023

  • "Experimenteller Vergleich der bildgebenden und globalen UV/Vis-Spektroskopie zur Charakterisierung der Mikromischung in einem Kaskadenmischer", Xuan My Le, Master thesis, 2023

  • "Comparison of the Lattice-Boltzmann Method and Finite Volume Method in continuously operated static mixers - a CFD benchmark study", Roman Neubauer, Master thesis, 2023

  • "Erstellung einer 1D- und 3D-CFD Methodik zur Berechnung und Optimierung einer neuen innovativen Wärmetauscher-Technologie im Motorsport", Hendrik Doß, Master thesis, 2022

  • "Experimentelle Untersuchung des Mischverhaltens in einem Milli-Kaskadenmischer bei kleinen Reynoldszahlen mit Hilfe der konfokalen Laserscanning-Mikroskopie", Sabrina Bauschmann, Bachelor thesis, 2022

  • "Effect of a Chemical Reaction on Grid Convergence of a Direct Numerical Simulation", Chandrahas Rao Sampelli, Project thesis, 2022

  • "Experimental Investigations of Mixing in a Split and Recombine Mixer using Confocal Laser Scanning Microscopy", Nithin Thonakkara James, Project Work, 2021

  • "Numerische Simulation der Mischleistung in einem strukturierten Rohrreaktor bei einem hohen Viskositätsverhältnis der Teilströme", Vincent Bernemann, Master thesis, 2021

  • "Experimentelle Untersuchung der Übertragbarkeit eines Mischprozesses vom Labordissolver auf eine duale asymmetrische Zentrifuge bei wässrigen Lacksystemen", Gerrit Spiller, Master thesis, 2021

  • „Numerische Simulation einer parallel-kompetitiven chemischen Reaktion mit steifem Differentialgleichungssystem in einem mikro-strukturierten Strömungskanal bei kleinen Reynoldszahlen", Tobias Freund, Master thesis, 2021

  • "Comparison of Active and Passive Micro Mixers Designed for Asymmetric Mixing Tasks", Kayla Reata Dittmer, Bachelor thesis, 2020

  • "Experimental Analysis of the Mixing Performance in Micro Channels at High Volume Flow Ratios and Low Reynolds Numbers", Rieke Schlütemann, Bachelor thesis, 2020

Oral and Poster Presentation

Lectures

  • Frey, T., Hoffmann, M., Schlüter, M.: "Experimental and CFD Study on Local Selectivity Distributions in a Stiff Reactive System", 14th ECCE and 7th ECAB, Berlin, 2023, lecture.

  • Frey, T., Grabellus, M., Le, X. M., Hoffmann, M., Herbstritt, F., Grünewald, M., Schlüter, M.: "Local interpretation of micro mixing through the Villermaux-Dushman reaction and the imaging UV-Vis spectroscopy", 17th European Conference on Mixing, Porto, 2023, lecture.

  • Schwarz, S.; Grünewald, M.; Biessey, P.; Frey, T.; Schlüter, M.; Hoffmann, M.: "CFD-based compartment modeling approach for continuous polymer reactors by means of the Mean-Age theory". (Bio)Process Engineering - a Key to Sustainable Development, joint event of ProcessNet, DECHEMA-BioTechNet Jahrestagungen 2022, 13th ESBES Symposium, Aachen, 2022, lecture.

  • Frey, T.; Hoffmann, M.; Schlüter, M.: "Visualizing Reactive Mixing Phenomena with the Novel Imaging UV/Vis Spectroscopy in Asymmetric and Transient Flows". (Bio)Process Engineering - a Key to Sustainable Development, joint event of ProcessNet, DECHEMA-BioTechNet Jahrestagungen 2022, 13th ESBES Symposium, Aachen, 2022, lecture.

  • Frey, T.; Hoffmann, M.; Schlüter, M.: "Visualizing Reactive Mixing Phenomena in Milli and Micro Channels". NAMF Mixing XXVII, virtual, 2022, lecture.

  • Frey, T.; Schwarz, S.; Biessey, P.; Hoffmann, M.; Grünewald, M; Schlüter, M.: "Modeling Polymer Fouling with an Euler-Lagrangian Approach in a Milli-Reactor with Static Mixing Elements". 13th ECCE, virtual, 2021, lecture.

Poster Presentations

  • Frey, T.; Schwarz, S.; Hoffmann, M.; Grünewald, M.; Schlüter, M.: "CFD unterstützte Auslegung und Compartment modellierung eines kontinuierlich betriebenen Reaktorsystems für Polymerisationsreaktionen". Jahrestreffen der ProcessNet-Fachgemeinschaft "Prozess-, Apparate- und Anlagentechnik", Frankfurt a. M., 2022, poster presentation.

  • Schwarz, S.; Frey, T.; Hoffmann, M.; Biessey, P.; Schlüter, M.; Grünewald, M: "CFD-based compartment modeling of static mixing elements for continuous polymer reactors by means of the Mean-Age theory". Annual Meeting on Reaction Engineering and ProcessNet Subject Division Heat and Mass Transfer 2022, Würzburg, 2022, poster presentation.

  • Frey, T.; Hoffmann, M.; Schlüter, M.: "A DNS Approach to high-Schmidt-Number problems in Reactive Micro- and Milli Systems". NAMF Mixing XXVII, virtual, 2022, poster presentation.

  • Schwarz, S.; Frey, T.; Hoffmann, M.; Biessey, P.; Schlüter, M.; Grünewald, M: "Compartmentmodellierung von statischen Mischelementen mithilfe der Mean-Age Theorie". Jahrestreffen der ProcessNet-Fachgemeinschaft "Prozess-, Apparate- und Anlagentechnik", virtual, 2021, poster presentation.

  • Frey, T.; Schwarz, S.; Seithümmer, V.; Bissey, P.; Hoffmann, M.; Grünewald, M.; Schlüter, M.: "Numerische Strömungssimulation zum Einfluss auf den Umsatz und die Selektivität einer Polymerisationsreaktion". Jahrestreffen der ProcessNet-Fachgemeinschaft "Prozess-, Apparate- und Anlagentechnik", virtual, 2020, poster presentation.

Publications

2023

  • Schwarz, S.; Frey, T.; Hoffmann, M.; Grünewald, M.; Schlüter, M. (2023). CFD-Based Compartment Modeling of Continuous Polymer Reactors in Milli-Structured Apparatuses by Use of the Mean Age Theory. Industrial & Engineering Chemistry Research. [Abstract] [doi]

2022

  • Frey T.; Hoffmann M.; Schlüter M. (2022). Visualizing Reactive Mixing Phenomena with the Novel Imaging UV-vis Spectroscopy in Asymmetric and Transient Flows. Chemie Ingenieur Technik. 94. (9), 1222-1223 [Abstract] [doi]

  • Frey T.; Kexel F.; Dittmer K.R.; Bohne S.; Hoffmann M.; Trieu H.K.; Schlüter M. (2022). A Novel Approach for Visualizing Mixing Phenomena of Reactive Liquid-Liquid Flows in Milli- and Micro-Channels. Frontiers in Chemical Engineering. 4. 874019 [Abstract] [doi]

  • Schwarz, S.;, Grünewald, M.; Biessey, P.; Frey, T.; Schlüter, M.; Hoffmann, M. (2022). CFD-based compartment modeling approach for continuous polymer reactors by means of the mean-age theory. Chemie Ingenieur Technik. 94. (9), 1343 [Abstract] [doi]

2021

  • Frey, T.; Schlütemann R.; Schwarz, S.; Biessey, P.; Hoffmann, M.; Grünewald, M.; Schlüter, M. (2021). CFD analysis of asymmetric mixing at different inlet configurations of a split-and-recombine micro mixer. Journal of Flow Chemistry. 11. 599–609 [Abstract] [doi]

Frans Jan de Jong

Dr.-Ing. Frans Jan de Jong

2010 - 2015        Research Fellow at the IMS

Research Expertise

Influence of boundary layer flows on the structure of macromolecules fixed to a flat plate


Ingrid Haase

Ingrid Haase, M.Sc.

2020-2023       Research Fellow at the IMS

Research Expertise

Large Scale Bioreactors - Insight Into a Black Box


 

Sven Kastens

Dr.-Ing. Sven Kastens

2013 - 2018        Research Fellow at the IMS

Research Expertise

  • Experimental Investigation of Reactive Bubbly Flows - Influence of Boundary Layer Dynamics on Mass Transfer and Chemical Reactions (DFG Priority Project 1740)

  • Experimental investigation and modeling of local mass transfer rates in pure and contaminated Taylor flows (DFG Priority Project 1506)


Florian Kopf

Dr.-Ing. Florian Kopf

2010 - 2013        Research Fellow at the IMS

Research Expertise

Computational fluid dynamics and experimental analysis of transport phenomena in micro-bioreactors


Katrin Laqua

Dipl.-Ing. Katrin Laqua

2011 - 2017        Research Fellow at the IMS

Research Expertise

  • Experimental study of multiphase flows under extreme environmental conditions in combination to the oil spill 2010 in the Gulf of Mexico (C-IMAGE)

  • Description of the fluid pathways of a deep-sea blowout: From multiphase petroleum jet to a rising plume, to bubbles and drops

  • Description of methane hydrate formation

  • Determination of the bubble and drop size distribution with endoscopic Particle Image Velocimetry (PIV)

  • Determination of the physical properties and the composition of the multiphase mixture


Simon Matthes

Dr.-Ing. Simon Matthes

2017 - 2021        Research Fellow at the IMS

Research Expertise

Characterization of Fine Bubbles for Biocatalytic Processes


Christoph Meyer

Dipl.-Ing. Christoph Meyer

2010 - 2015        Research Fellow at the IMS

Research Expertise

  • Experimental investigation and modeling of local mass transfer rates in pure and contaminated Taylor flows (SPP-1506)

  • Study of transport processes at fluidic interfaces on microscale

  • Investigation of local mass transfer rates measuring the velocity and concentration fields simultaneously

  • Analysis of the local velocity field by micro-particle image velocimetry (µ-PIV) and local concentration field by laser-induced fluorescence (LIF) respectively

  • Investigation and influence of contaminations and surfactants on mass transfer

  • Modeling of local mass transfer rates of fluidic interfaces


Stefan Mosler

Dipl.-Math. Stefan Mosler

2010 - 2014        Research Fellow at the IMS

Research Expertise

Modelling, simulation and experimental analysis of two-phase flows in a Y-Y shaped microreactor


Christian-Ole Möller

Dipl.-Ing. Christian-Ole Möller

2012 - 2016        Research Fellow at the IMS

Research Expertise

  • Energy efficient multiphase processes

  • Development of novel structured packings

  • Mass transfer enhancement of multiphase apparatuses

  • Energy efficiency enhancement of multiphase apparatuses

  • Optimization of bubble column reactors

  • Experimental studies of hydrodynamics and mass transfer processes in multiphase apparatuses

Daniel Niehaus

Daniel Niehaus, M.Sc.

2019 - 2024        Research Fellow at the IMS

Research Expertise

Construction and characterisation of aerated biotechnological high-pressure reactors within the framework of the Protein Pressure Stability Impact (Prot. P.S.I.)


Simeon Pesch

Dr.-Ing. Simeon Pesch

2015 - 2020        Research Fellow at the IMS

Research Expertise

  • Center for the Integrated Modeling and Analysis of Gulf Ecosystems (C-IMAGE II, C-IMAGE III)

  • Experimental investigation and modeling of multiphase flow phenomena under extreme environmental conditions in relation to the deep-sea oil spill 2010 in the Gulf of Mexico


Steffen Richter

Dipl.-Wi.-Ing. Steffen Richter

2009 - 2018        Research Fellow at the IMS

Research Expertise

Industrial research for multiphase flow systems


Annika Rosseburg

Dr.-Ing. Annika Rosseburg

2013 - 2018        Research Fellow at the IMS

Research Expertise

  • Aerated stirred tank reactors

  • Scale-up and scale-down

  • Investigation of local and global flow structure, bubble size distribution, gas hold-up and mixing


Sophie Rüttinger

Dr.-Ing. Sophie Rüttinger

2014 - 2019        Research Fellow at the IMS

Research Expertise

Investigation of the influence of vortex structures on transport processes at fluidic interfaces (Priority Program 1740)


Claas Spille

Claas Spille, M.Sc.

2017 - 2021 Research Fellow at the IMS

Research Expertise


Nicolai Szeliga

Dr.-Ing. Nicolai Szeliga

2014 - 2019        Research Fellow at the IMS

Research Expertise

Safety-relevant analysis of the performance of centrifugal pumps, valves and inlet geometries, including stress-related events (SAVE)


Jens Timmermann

Dr.-Ing. Jens Timmermann

2012 - 2017        Research Fellow at the IMS

Research Expertise

Experimental Investigation of Reactive Bubbly Flows - Influence of Boundary Layer Dynamics on Mass Transfer and Chemical Reactions


Christian Urban

Dr.-Ing. Christian Urban

2011 - 2014        Research Fellow at the IMS

Research Expertise

CIWA - Condensation Induced Water Hammer