Dr.-Ing. Jürgen Fitschen

2018 - 2023        Research Fellow at the IMS

Boehringer Ingelheim Pharma GmbH & Co. KG
Bioprocess Development Biologicals

Binger Strasse 173

55216 Ingelheim am Rhein

Phone +49 7351 54-177970

Mail Dr. Jürgen Fitschen

Research Expertise

  • Large Scale Bioreactors

  • Characterization of Heterogeneities in Aerated Stirred Tank Reactors

  • Characterization of Mixing Time



  • Fitschen, J.; Hofmann, S.; Kursula, L.; Haase, I.; Wucherpfennig, T.; Schlüter, M. (2024). Advances in Characterization of Industrial Bioreactors for Cell Culture Process. Biopharmaceutical Manufacturing. [doi]


  • Fitschen, J.; Hofmann, S.; Wutz, J.; Kameke, A. v.; Hoffmann M.; Wucherpfennig T.; Schlüter, M. (2021). Novel Evaluation Method to Determine the Local Mixing Time Distribution in Stirred Tank Reactors. Chemical Engineering Science: X. 10. [Abstract] [doi]

  • Fitschen, J.; Maly, M.; Rosseburg, A.; Wutz, J.; Wucherpfennig, T.; Schlüter, M.; (2019). Influence of Spacing of Multiple Impellers on Power Input in an Industrial-Scale Aerated Stirred Tank Reactor. Chemie Ingenieur Technik. 91. 1794-1801 [Abstract] [doi]

  • Hofmann, S.; Buntkiel, L.; Rautenbach, R.; Gaugler, L.; Ma, Y.; Haase, I.; Fitschen, J.; Wucherpfennig, T.; Reinecke, S. F.; Hoffmann, M.; Takors, R.; Hampel, U.; Schlüter, M. (2024). Experimental analysis of lifelines in a 15,000 L bioreactor by means of Lagrangian Sensor Particles. Chemical Engineering Research and Design. 205. 695-712 [Abstract] [doi]

  • Hofmann, S.; Weiland, C.; Fitschen, J.; von Kameke, A., Hoffmann, M.; Schlüter, M. (2022). Lagrangian sensors in a stirred tank reactor: Comparing trajectories from 4D-Particle Tracking Velocimetry and Lattice-Boltzmann simulations. Chemical Engineering Journal. 449. [Abstract] [doi]

  • Matthes. S.; Merbach, T.; Fitschen, J.; Hoffmann, M.; Schlüter, M.; (2021). Influence of counterdiffusion effects on mass transfer coefficients in stirred tank reactors. Chemical Engineering Journal Advances. 8. [Abstract] [doi]

  • Rosseburg, A.; Fitschen, J.; Wutz, J.; Wucherpfennig, T.; Schlüter, M. (2018). Hydrodynamic inhomogeneities in large scale stirred tanks – Influence on mixing time. Chemical Engineering Science. 188. 208-220 [Abstract] [doi] [www]

  • Weiland, C.; Steuwe, E.; Fitschen, J.; Hoffmann, M.; Schlüter, M.; Padberg-Gehle, K.; von Kameke, A. (2023). Computational study of three-dimensional Lagrangian transport and mixing in a stirred tank reactor. Chemical Engineering Journal Advances. 14. [Abstract] [doi]

  • Weiland, C; Salli, M.; Fitschen, J.; Hoffmann, M.; Schlüter, M. (2023). Introduction of novel characteristic time quantities to describe chemical reactors. Chemical Engineering Journal Advances. 16. [Abstract] [doi]


  • Gaugler, L; Mast, Y.; Fitschen, J.; Hofmann, S.; Hoffmann, M.; Schlüter, M. (2022). Scaling-down biopharmaceutical production processes via a single multi-compartment bioreactor (SMCB). Engineering in Life Sciences. 12 [Abstract] [doi]


  • Bernemann, V.; Fitschen, J.; Leupold, M.; Scheibenbogen, K.-H.; Maly, M.; Hoffmann, M.; Wucherpfennig, T.; Schlüter, M. (2024). Characterization Data for the Establishment of Scale-Up and Process Transfer Strategies between Stainless Steel and Single-Use Bioreactors. Fluids. 9. (5), [Abstract] [doi] [www]


  • Kursula, L.; Kexel, F.; Fitschen, J.; Hoffmann, M.; Schlüter, M.; Kameke, A.v.; (2022). Unsteady Mass Transfer in Bubble Wakes Analyzed by Lagrangian Coherent Structures in a Flat-Bed Reactor. Processes. 10. (12), [Abstract] [doi]

  • Kuschel, M.; Fitschen, F.; Hoffmann, M.; Kameke, A. v.; Wucherpfennig, T.; Schlüter, M. (2021). Validation of Novel Lattice Boltzmann Large Eddy Simulations (LB LES) for Equipment Characterization in Biopharma. Processes. 9. (6), 950 [Abstract] [doi]