Multi-Patch Sequences in Magnetic Particle Imaging

sketch of a multi-patch imaging sequence
Sketch of a multi-patch imaging sequence.

In this project we develop multi-patch imaging sequences and reconstruction algorithms for enlarged measuring fields in magnetic particle imaging (MPI). The regular field-of-view (FOV) in MPI is limited due to physiological constraints such as tissue heating and nerve stimulation. In practice typical FOV are in the range of 2x2x1 cm³. In order to scan larger regions it is possible to shift the FOV to different positions and scan various smaller FOV, which can later be combined to a joint 3D dataset. Especially the reconstruction of multi-patch data is a computationally intensive and memory demanding task. In this project we develop algorithms for efficient reconstruction of multi-patch MPI data.

To reduce calibration time and speed up image reconstruction, we have introduced a number of different methods, including reducing the number of system matricessystem matrix warping, and overscan extrapolation.

Contact

Project Publications

  • 30
    Hackelberg, N.; Boberg, M.; Knopp, T.
    GPU Accelerated Multi-Patch Reconstruction
    2025 Contribution to Proceeding In "14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)"
    Booktitle , 14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)Volume11, Page 1-2
  • 29
    Reiss, S.; Thieben, F.; Faltinath, J.; Knopp, T.; Boberg, M.
    Model-Based Reconstruction in MPI accounting for Field Imperfections
    2025 Contribution to Proceeding In "14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)"
    Booktitle , 14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)Volume11, Page 1-2
  • 28
    Scheffler, K.; Boberg, M.; Knopp, T.
    Extrapolation of System Matrices in Magnetic Particle Imaging
    2023 Article IEEE Transactions on Medical Imaging
    Journal IEEE Transactions on Medical Imaging, 42 (4): 1121 - 1132
  • 27
    Reducing displacement artifacts in multi-patch magnetic particle imaging
    2023 Contribution to Proceeding In "10th International Congress on Industrial and Applied Mathematics (ICIAM 2023)"
    Booktitle 10th International Congress on Industrial and Applied Mathematics (ICIAM 2023), Page 05026
  • 26
    Szwargulski, P.; Knopp, T.; Boberg, M.; Salamon, J.; Scheitenberger, V.; Göttsche, T.; Linemann, R.; Wegner, F.; Friedrich, T.; Barkhausen, J.; Buzug, T. M.; Ahlborg, M.
    First Complex Trials Using a Dedicated Balloon Catheter for Magnetic Particle Imaging
    2022 Contribution to Proceeding In "11th International Workshop on Magnetic Particle Imaging (IWMPI 2022)"
    Booktitle , 11th International Workshop on Magnetic Particle Imaging (IWMPI 2022)Volume8, Page 1-4
  • 25
    Scheffler, K.; Boberg, M.; Knopp, T.
    Boundary artifact reduction by extrapolating system matrices outside the field-of-view in joint multi-patch MPI
    2022 Contribution to Proceeding In "11th International Workshop on Magnetic Particle Imaging (IWMPI 2022)"
    Booktitle , 11th International Workshop on Magnetic Particle Imaging (IWMPI 2022)Volume8, Page 1-3
  • 24
    Zdun, L.; Boberg, M.; Brandt, C.
    Fast and artifact reducing joint multi-patch MPI reconstruction
    2022 Contribution to Proceeding In "11th International Workshop on Magnetic Particle Imaging (IWMPI 2022)"
    Booktitle , 11th International Workshop on Magnetic Particle Imaging (IWMPI 2022)Volume8, Page 1-4
  • 23
    Zdun, L.; Boberg, M.; Brandt, C.
    Joint multi-patch reconstruction: fast and improved results by stochastic optimization
    2022 Article International Journal on Magnetic Particle Imaging
    Journal International Journal on Magnetic Particle Imaging, 8 (2): 1-8
  • 22
    Boberg, M.; Gdaniec, N.; Möddel, M.; Szwargulski, P.; Knopp, T.
    Suppression of Motion Artifacts in Multi-Patch Magnetic Particle Imaging of a Phantom with Periodic Motion
    2022 Contribution to Proceeding In "SIAM Conference on Imaging Science (IS22)"
    Booktitle SIAM Conference on Imaging Science (IS22)
  • 21
    Gdaniec, N.; Boberg, M.; Möddel, M.; Szwargulski, P.; Knopp, T.
    Suppression of Motion Artifacts Caused by Temporally Recurring Tracer Distributions in Multi-Patch Magnetic Particle Imaging
    2020 Article IEEE Transactions on Medical Imaging
    Journal IEEE Transactions on Medical Imaging, 39 (11): 3548-3558
  • 20
    Reducing displacement artifacts by warping system matrices in efficient joint multi-patch magnetic particle imaging
    2020 Contribution to Proceeding In "10th International Workshop on Magnetic Particle Imaging (IWMPI 2020)"
    Booktitle , 10th International Workshop on Magnetic Particle Imaging (IWMPI 2020)Volume6, Page 1-3
  • 19
    Boberg, M.; Knopp, T.; Szwargulski, P.; Möddel, M.
    Generalized MPI Multi-Patch Reconstruction using Clusters of similar System Matrices
    2020 Article IEEE Transactions on Medical Imaging
    Journal IEEE Transactions on Medical Imaging, 39 (5): 1347-1358
  • 18
    Szwargulski, P.; Möddel, M.; Gdaniec, N.; Knopp, T.
    Efficient Joint Image Reconstruction of Multi-Patch Data reusing a Single System Matrix in Magnetic Particle Imaging
    2019 Article IEEE Transactions on Medical Imaging
    Journal IEEE Transactions on Medical Imaging, 38 (4): 932-944
  • 17
    Boberg, M.; Möddel, M.; Knopp, T.
    Magnetic field based system matrix corrections for multi-patch MPI reconstructions
    2019 Contribution to Proceeding In "9th International Congress on Industrial and Applied Mathematics (ICIAM 2019)"
    Booktitle 9th International Congress on Industrial and Applied Mathematics (ICIAM 2019), Page 333
  • 16
    Magnetic Field Based Similarity Measure for System Matrices in Magnetic Particle Imaging
    2019 Contribution to Proceeding In "9th International Workshop on Magnetic Particle Imaging (IWMPI 2019)"
    Booktitle 9th International Workshop on Magnetic Particle Imaging (IWMPI 2019), Page 73-74
  • 15
    Szwargulski, P.; Gdaniec, N.; Graeser, M.; Möddel, M.; Griese, F.; Krishnan, K. M.; Buzug, T. M.; Knopp, T.
    Moving table magnetic particle imaging: a stepwise approach preserving high spatio-temporal resolution
    2018 Article Journal of Medical Imaging
    Journal Journal of Medical Imaging, 5 (4): 046002
  • 14
    Szwargulski, P.; Gdaniec, N.; Graeser, M.; Möddel, M.; Griese, F.; Knopp, T.
    Erweiterung des Bildgebungsbereiches bei der Magnetpartikelbildgebung durch externe axiale Verschiebungen
    2018 Contribution to Proceeding In "BVM Workshop 2018"
    Booktitle BVM Workshop 2018, Page 202
  • 13
    Szwargulski, P.; Gdaniec, N.; Graeser, M.; Möddel, M.; Griese, F.; Knopp, T.
    Enlarging the field of view in magnetic particle imaging using a moving table approach
    2018 Contribution to Proceeding In "Medical Imaging 2018: Biomedical Applications in Molecular, Structural, and Functional Imaging"
    Booktitle , Medical Imaging 2018: Biomedical Applications in Molecular, Structural, and Functional ImagingVolume10578, Page 10578 - 10578 - 7
    SPIE
  • 12
    Szwargulski, P.; Gdaniec, N.; Möddel, M.; Graeser, M.; Knopp, T.
    Reconstruction of an object moved continuously through the Field of View in MPI
    2018 Contribution to Proceeding In "8th International Workshop on Magnetic Particle Imaging (IWMPI 2018)"
    Booktitle 8th International Workshop on Magnetic Particle Imaging (IWMPI 2018), Page 137-138
  • 11
    Szwargulski, P.; Gdaniec, N.; Knopp, T.
    Schnelle adaptive Aufnahme von Magnetic-Particle-Imaging Daten durch Nutzung mehrerer Gradientenstärken
    2018 Contribution to Proceeding In "BVM Workshop 2018"
    Booktitle BVM Workshop 2018, Page 373
  • 10
    Ahlborg, M.; Kaethner, C.; Szwargulski, P.; Knopp, T.; Buzug, T. M.
    Reusing System Matrices of Patches in Magnetic Particle Imaging via Mirroring
    2018 Contribution to Proceeding In "8th International Workshop on Magnetic Particle Imaging (IWMPI 2018)"
    Booktitle 8th International Workshop on Magnetic Particle Imaging (IWMPI 2018), Page 51-52
  • 9
    Ahlborg, M.; Kaethner, C.; Szwargulski, P.; Knopp, T.; Buzug, T. M.
    Patches in Magnetic Particle Imaging
    2018 Contribution to Proceeding In "BVM Workshop 2018"
    Booktitle BVM Workshop 2018, Page 169
  • 8
    Gdaniec, N.; Szwargulski, P.; Knopp, T.
    Fast Multi-Resolution Data Acquisition for Magnetic Particle Imaging using Adaptive Feature Detection
    2017 Article Medical Physics
    Journal Medical Physics, 44 (12): 6456-6460
  • 7
    Szwargulski, P.; Hofmann, M.; Gdaniec, N.; Knopp, T.
    Fast Implicit Reconstruction of Focus Field Data in MPI
    2016 Contribution to Proceeding In "6th International Workshop on Magnetic Particle Imaging (IWMPI 2016)"
    Booktitle 6th International Workshop on Magnetic Particle Imaging (IWMPI 2016), Page 176
  • 6
    Weber, A.; Werner, F.; Weizenecker, J.; Buzug, T. M.; Knopp, T.
    Artifact free reconstruction with the system matrix approach by overscanning the field-free-point trajectory in magnetic particle imaging
    2016 Article Physics in Medicine and Biology
    Journal Physics in Medicine and Biology, 61 (2): 475-487
  • 5
    Szwargulski, P.; Hofmann, M.; Gdaniec, N.; Knopp, T.
    The Influence of Field Distortions on Multi-Patch Image Reconstruction in Magnetic Particle Imaging
    2016 Contribution to Proceeding In "IEEE Nuclear Science Symp. and Medical Imaging Conf.(NSS/MIC)"
    Booktitle IEEE Nuclear Science Symp. and Medical Imaging Conf.(NSS/MIC)
  • 4
    Ahlborg, M.; Kaethner, C.; Knopp, T.; Szwargulski, P.; Buzug, T. M.
    Using data redundancy gained by patch overlaps to reduce truncation artifacts in magnetic particle imaging
    2016 Article Physics in Medicine and Biology
    Journal Physics in Medicine and Biology, 61 (12): 4583-4598
  • 3
    Knopp, T.; Kaul, M. G.
    MPI focus field experiments using non-overlapping focus-field patches
    2015 Contribution to Proceeding In "5th International Workshop on Magnetic Particle Imaging (IWMPI 2015)"
    Booktitle 5th International Workshop on Magnetic Particle Imaging (IWMPI 2015), Page 1pp
  • 2
    Knopp, T.; Them, K.; Werner, F.; Hofmann, M.
    Reusing System Matrices at different Focus Field Positions in Magnetic Particle Imaging
    2015 Contribution to Proceeding In "Biomedical Engineering / Biomedizinische Technik"
    Booktitle , Biomedical Engineering / Biomedizinische TechnikVolume60
    Publisher De Gruyter
  • 1
    Knopp, T.; Them, K.; Kaul, M. G.; Gdaniec, N.
    Joint reconstruction of non-overlapping magnetic particle imaging focus-field data
    2015 Article Physics in Medicine and Biology
    Journal Physics in Medicine and Biology, 60 : L15