Multi-Patch Sequences in Magnetic Particle Imaging

In this project we develop multi-patch imaging sequences and reconstruction algorithms for enlarged measuring fields in magnetic particle imaging (MPI). The regular field-of-view (FOV) in MPI is limited due to physiological constraints such as tissue heating and nerve stimulation. In practice typical FOV are in the range of 2x2x1 cm³. In order to scan larger regions it is possible to shift the FOV to different positions and scan various smaller FOV, which can later be combined to a joint 3D dataset. Especially the reconstruction of multi-patch data is a computationally intensive and memory demanding task. In this project we develop algorithms for efficient reconstruction of multi-patch MPI data.

To reduce calibration time and speed up image reconstruction, we have introduced a number of different methods, including reducing the number of system matricessystem matrix warping, and overscan extrapolation.

Sketch of a multi-patch imaging sequence.

Publications

[164778]
Title: First Complex Trials Using a Dedicated Balloon Catheter for Magnetic Particle Imaging.
Written by: P. Szwargulski, T. Knopp, M. Boberg, J. Salamon, V. Scheitenberger, T. Göttsche, R. Linemann, F. Wegner, T. Friedrich, J. Barkhausen, T. M. Buzug, and M. Ahlborg
in: <em>International Journal on Magnetic Particle Imaging</em>. (2022).
Volume: <strong>8</strong>. Number: (1),
on pages: 1-4
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DOI: 10.18416/IJMPI.2022.2203004
URL: https://journal.iwmpi.org/index.php/iwmpi/article/view/385
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Note: inproceedings, multi-patch, multi-contrast

Abstract: A recent work introduced a balloon catheter from a polymer mixed with magnetic nanoparticles that was visible in magnetic particle imaging (MPI) in initial trials. In this work, dynamic multi-patch and multi-contrast experiments were performed to validate the usability of the balloon catheter for complex application scenarios. In both cases, the balloon was successfully imaged, although there are limitations in resolution and dynamic imaging range.