Prof. Dr.-Ing. Tobias Knopp

Universitätsklinikum Hamburg-Eppendorf (UKE)
Sektion für Biomedizinische Bildgebung
Lottestraße 55
2ter Stock, Raum 209
22529 Hamburg
- Postanschrift -

Technische Universität Hamburg (TUHH)
Institut für Biomedizinische Bildgebung
Gebäude E, Raum 4.044
Am Schwarzenberg-Campus 3
21073 Hamburg

Tel.: 040 / 7410 56794
Fax: 040 / 7410 45811
E-Mail: t.knopp(at)uke.de
E-Mail: tobias.knopp(at)tuhh.de
ORCID: https://orcid.org/0000-0002-1589-8517

 

Roles

  • Head of the Institute for Biomedical Imaging
  • Editor-in-chief of the International Journal on Magnetic Particle Imaging (IJMPI)

Consulting Hours

  • On appointment

Research Interests

  • Tomographic Imaging
  • Image Reconstruction
  • Signal- and Image Processing
  • Magnetic Particle Imaging

Curriculum Vitae

Tobias Knopp received his Diplom degree in computer science in 2007 and his PhD in 2010, both from the University of Lübeck with highest distinction. For his PHD on the tomographic imaging method Magnetic Particle Imaging (MPI) he was awarded with the Klee award from the DGBMT (VDE) in 2011. From 2010 until 2011 he led the MAPIT project at the University of Lübeck and published the first scientific book on MPI. In 2011 he joined Bruker Biospin to work on the first commercially available MPI system. From 2012 until 2014 he worked at Thorlabs in the field of Optical Coherence Tomography (OCT) as a software developer. In 2014 he has been appointed as Professor for experimental Biomedical Imaging at the University Medical Center Hamburg-Eppendorf and the Hamburg University of Technology.

Publications

[191081]
Title: Comparison of Reconstruction Methods for Elongated Multi-Patch Sequences in Magnetic Particle Imaging.
Written by: M. Möddel, L. Jensen, M. Boberg, and T. Knopp
in: <em>13th International Workshop on Magnetic Particle Imaging (IWMPI 2024)</em>. (2024).
Volume: <strong>10</strong>. Number: (1 Suppl 1),
on pages: 1
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URL: https://www.journal.iwmpi.org/index.php/iwmpi/article/view/741
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Note: inproceedings

Abstract: Magnetic particle imaging systems utilize one or more dynamic drive fields to excite the magnetization of the nanoparticles, along with a static selection field that spatially encodes the resulting magnetization signal. This selection field effectively suppresses signal generation outside a smaller volume surrounding the field-free region (FFR), while the drive fields swiftly move this region. However, the practical size of the possible field of view attainable with these single-patch sequences is limited. To upscale an MPI system, one can increase the effective field of view through two methods: moving the object or utilizing additional low-frequency focus fields. These extra fields can continuously or stepwise relocate the position of the FFR. Especially elongated sequences that involve slow and continuous shifts of focus fields along with simultaneous movements of drive fields in the FFR are of particular interest due to their flexibility and operability at full duty cycle. For reconstruction one either considers the entire sequence as a single patch or as a collection of multiple patches, each of which does impact image artifacts, reconstruction time, and calibration complexity. Dependent of the interpretation of the raw data particular challenges include the processing of the measured data, which is no longer periodic, and the length of the data sets that is now determined by the duration of the focus field sequence rather than by the comparably short drive field excitation cycles. In this work, various methods for reconstructing elongated multi-patch sequences are examined and contrasted based on their impact on image artifacts, runtime, and calibration complexity.