Prof. Dr.-Ing. Tobias Knopp

Universitätsklinikum Hamburg-Eppendorf (UKE)
Sektion für Biomedizinische Bildgebung
Lottestraße 55
2ter Stock, Raum 209
22529 Hamburg
- Postanschrift -

Technische Universität Hamburg (TUHH)
Institut für Biomedizinische Bildgebung
Gebäude E, Raum 4.044
Am Schwarzenberg-Campus 3
21073 Hamburg

Tel.: 040 / 7410 56794
Fax: 040 / 7410 45811
E-Mail: t.knopp(at)uke.de
E-Mail: tobias.knopp(at)tuhh.de
ORCID: https://orcid.org/0000-0002-1589-8517

 

Roles

  • Head of the Institute for Biomedical Imaging
  • Editor-in-chief of the International Journal on Magnetic Particle Imaging (IJMPI)

Consulting Hours

  • On appointment

Research Interests

  • Tomographic Imaging
  • Image Reconstruction
  • Signal- and Image Processing
  • Magnetic Particle Imaging

Curriculum Vitae

Tobias Knopp received his Diplom degree in computer science in 2007 and his PhD in 2010, both from the University of Lübeck with highest distinction. For his PHD on the tomographic imaging method Magnetic Particle Imaging (MPI) he was awarded with the Klee award from the DGBMT (VDE) in 2011. From 2010 until 2011 he led the MAPIT project at the University of Lübeck and published the first scientific book on MPI. In 2011 he joined Bruker Biospin to work on the first commercially available MPI system. From 2012 until 2014 he worked at Thorlabs in the field of Optical Coherence Tomography (OCT) as a software developer. In 2014 he has been appointed as Professor for experimental Biomedical Imaging at the University Medical Center Hamburg-Eppendorf and the Hamburg University of Technology.

Publications

[180974]
Title: Model-based Calibration and Image Reconstruction with Immobilized Nanoparticles.
Written by: H. Albers, F. Thieben, M. Boberg, K. Scheffler, T. Knopp, and T. Kluth
in: <em>International Journal on Magnetic Particle Imaging</em>. (2023).
Volume: <strong>9</strong>. Number: (1),
on pages: 1-5
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DOI: 10.18416/IJMPI.2023.2303002
URL: https://journal.iwmpi.org/index.php/iwmpi/article/view/592
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Note: inproceedings, magneticfield, model-based

Abstract: The model-based reconstruction problem is still one of the key challenges in magnetic particle imaging (MPI) when using multi-dimensional Lissajous-type excitations. One aspect, which is often highlighted in the literature, is the magnetization behavior of the magnetic nanoparticles in fluids, which is typically modeled by a coupling of Brown and N\'{e}el rotation mechanisms. Another aspect, which is at least as important as the particle model itself but sometimes treated less prominently, is a very careful calibration of the model input, respectively the scanner parameters such as analog filter and applied magnetic fields. The careful consideration of both aspects is the essential requirement for a proper solution to the model-based problem. In the present work we combine calibrated scanner components with polydisperse particle models for immobilized nanoparticles to derive a model-based system function and an efficient calibration routine. It is experimentally validated on the Bruker preclinical MPI system using 2D Lissjous trajectories.