Prof. Dr.-Ing. Tobias Knopp

Universitätsklinikum Hamburg-Eppendorf (UKE)
Sektion für Biomedizinische Bildgebung
Lottestraße 55
2ter Stock, Raum 209
22529 Hamburg
- Postanschrift -

Technische Universität Hamburg (TUHH)
Institut für Biomedizinische Bildgebung
Gebäude E, Raum 4.044
Am Schwarzenberg-Campus 3
21073 Hamburg

Tel.: 040 / 7410 56794
Fax: 040 / 7410 45811
E-Mail: t.knopp(at)uke.de
E-Mail: tobias.knopp(at)tuhh.de
ORCID: https://orcid.org/0000-0002-1589-8517

Roles

  • Head of the Institute for Biomedical Imaging
  • Editor-in-chief of the International Journal on Magnetic Particle Imaging (IJMPI)

Consulting Hours

  • On appointment

Research Interests

  • Tomographic Imaging
  • Image Reconstruction
  • Signal- and Image Processing
  • Magnetic Particle Imaging

Curriculum Vitae

Tobias Knopp received his Diplom degree in computer science in 2007 and his PhD in 2010, both from the University of Lübeck with highest distinction. For his PHD on the tomographic imaging method Magnetic Particle Imaging (MPI) he was awarded with the Klee award from the DGBMT (VDE) in 2011. From 2010 until 2011 he led the MAPIT project at the University of Lübeck and published the first scientific book on MPI. In 2011 he joined Bruker Biospin to work on the first commercially available MPI system. From 2012 until 2014 he worked at Thorlabs in the field of Optical Coherence Tomography (OCT) as a software developer. In 2014 he has been appointed as Professor for experimental Biomedical Imaging at the University Medical Center Hamburg-Eppendorf and the Hamburg University of Technology.

Journal Publications

[191175]
Title: RegularizedLeastSquares.jl: Modality Agnostic Julia Package for Solving Regularized Least Squares Problems.
Written by: N. Hackelberg, M. Grosser, A. Tsanda, F. Mohn, K. Scheffler, M. Möddel, and T. Knopp
in: <em>International Journal on Magnetic Particle Imaging</em>. (2024).
Volume: <strong>10</strong>. Number: (1 Suppl 1),
on pages: 1-4
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DOI: https://doi.org/10.18416/IJMPI.2024.2403028
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Note: inproceedings, reconstruction, opensoftware, generalsoftware

Abstract: Image reconstruction in Magnetic Particle Imaging (MPI) is an ill-posed linear inverse problem. A standard method for solving such a problem is the regularized least squares approach, which uses, a regularization function to reduce the impact of measurement noise in the reconstructed image by leveraging prior knowledge. Various optimization algorithms, including the Kazcmarz method or the Alternating Direction Method of Multipliers (ADMM), and regularization functions, such asl2or Fused Lasso priors have been employed. Therefore, the creation and implementation of cutting-edge image reconstruction techniques necessitate a robust and adaptable optimization framework. In this work, we present the open-source Julia package RegularizedLeastSquares.jl, which provides a large selection of common optimization algorithms and allows flexible inclusion of regularization functions. These features enable the package to achieve state-of-the-art image reconstruction in MPI.