[183662] |
Title: Development of Optimized Magnetic Particle Imaging Tracers Utilizing Genetically Engineered Magnetosomes. |
Written by: F. Thieben, F. Mickoleit, S. Tessaro, P. Ludewig, D. Schüler, J.R. Garbayo, R. Uebe, and T. Knopp |
in: <em>International Journal on Magnetic Particle Imaging</em>. (2023). |
Volume: <strong>9</strong>. Number: (1 Suppl 1), |
on pages: 1-4 |
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DOI: 10.18416/IJMPI.2023.2303066 |
URL: https://www.journal.iwmpi.org/index.php/iwmpi/article/view/626 |
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Note: inproceedings
Abstract: The imaging quality of Magnetic Particle Imaging (MPI) is not just limited by the MPI system but also by the quality of available tracers. The tracer quality can be improved by optimizing the shape, core size and shell of the nanoparticles. However, such a defined synthesis is quiet challenging. Biogenic magnetic nanoparticles, so-called magnetosomes, synthesized by magnetotoactic bacteria, might provide a promising alternative. In this study, magnetosomes isolated from different Magnetospirillum gryphiswaldense mutant strains biomineralizing particles with varying core diameters were investigated with regard to their usability as tracers for MPI.