Prof. Dr.-Ing. Tobias Knopp

Universitätsklinikum Hamburg-Eppendorf (UKE)
Sektion für Biomedizinische Bildgebung
Lottestraße 55
2ter Stock, Raum 209
22529 Hamburg
- Postanschrift -

Technische Universität Hamburg (TUHH)
Institut für Biomedizinische Bildgebung
Gebäude E, Raum 4.044
Am Schwarzenberg-Campus 3
21073 Hamburg

Tel.: 040 / 7410 56794
Fax: 040 / 7410 45811
E-Mail: t.knopp(at)uke.de
E-Mail: tobias.knopp(at)tuhh.de
ORCID: https://orcid.org/0000-0002-1589-8517

 

Roles

  • Head of the Institute for Biomedical Imaging
  • Editor-in-chief of the International Journal on Magnetic Particle Imaging (IJMPI)

Consulting Hours

  • On appointment

Research Interests

  • Tomographic Imaging
  • Image Reconstruction
  • Signal- and Image Processing
  • Magnetic Particle Imaging

Curriculum Vitae

Tobias Knopp received his Diplom degree in computer science in 2007 and his PhD in 2010, both from the University of Lübeck with highest distinction. For his PHD on the tomographic imaging method Magnetic Particle Imaging (MPI) he was awarded with the Klee award from the DGBMT (VDE) in 2011. From 2010 until 2011 he led the MAPIT project at the University of Lübeck and published the first scientific book on MPI. In 2011 he joined Bruker Biospin to work on the first commercially available MPI system. From 2012 until 2014 he worked at Thorlabs in the field of Optical Coherence Tomography (OCT) as a software developer. In 2014 he has been appointed as Professor for experimental Biomedical Imaging at the University Medical Center Hamburg-Eppendorf and the Hamburg University of Technology.

Publications

[146886]
Title: Bias-reduction for sparsity promoting regularization in Magnetic Particle Imaging.
Written by: L. Nawwas, M. Möddel, T. Knopp, and C. Brandt
in: <em>International Journal on Magnetic Particle Imaging</em>. (2020).
Volume: <strong>6</strong>. Number: (2),
on pages: 1-2
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DOI: 10.18416/IJMPI.2020.2009041
URL: https://journal.iwmpi.org/index.php/iwmpi/article/view/281
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Note: inproceedings, artifact

Abstract: Magnetic Particle Imaging (MPI) is a tracer based medical imaging modality with great potential due to its high sensitivity, high spatial and temporal resolution, and ability to quantify the tracer concentration. Image reconstruction in MPI is an ill-posed problem that can be addressed by regularization methods that each lead to a bias. Reconstruction bias in MPI is most apparent in a mismatch between true and reconstructed tracer distribution. This is expressed globally in the spatial support of the distribution and locally in its intensity values. In this work, MPI reconstruction bias and its impact are investigated and a two-step debiasing method with significant bias reduction capabilities is introduced.