Prof. Dr.-Ing. Tobias Knopp

Universitätsklinikum Hamburg-Eppendorf (UKE)
Sektion für Biomedizinische Bildgebung
Lottestraße 55
2ter Stock, Raum 209
22529 Hamburg
- Postanschrift -

Technische Universität Hamburg (TUHH)
Institut für Biomedizinische Bildgebung
Gebäude E, Raum 4.044
Am Schwarzenberg-Campus 3
21073 Hamburg

Tel.: 040 / 7410 56794
Fax: 040 / 7410 45811
E-Mail: t.knopp(at)
E-Mail: tobias.knopp(at)



  • Head of the Institute for Biomedical Imaging
  • Editor-in-chief of the International Journal on Magnetic Particle Imaging (IJMPI)

Consulting Hours

  • On appointment

Research Interests

  • Tomographic Imaging
  • Image Reconstruction
  • Signal- and Image Processing
  • Magnetic Particle Imaging

Curriculum Vitae

Tobias Knopp received his Diplom degree in computer science in 2007 and his PhD in 2010, both from the University of Lübeck with highest distinction. For his PHD on the tomographic imaging method Magnetic Particle Imaging (MPI) he was awarded with the Klee award from the DGBMT (VDE) in 2011. From 2010 until 2011 he led the MAPIT project at the University of Lübeck and published the first scientific book on MPI. In 2011 he joined Bruker Biospin to work on the first commercially available MPI system. From 2012 until 2014 he worked at Thorlabs in the field of Optical Coherence Tomography (OCT) as a software developer. In 2014 he has been appointed as Professor for experimental Biomedical Imaging at the University Medical Center Hamburg-Eppendorf and the Hamburg University of Technology.


Title: Toward employing the full potential of magnetic particle imaging: exploring visualization techniques and clinical use cases for real-time 3D vascular imaging. <em>Medical Imaging 2019: Biomedical Applications in Molecular, Structural, and Functional Imaging</em>
Written by: R. Werner, D. Weller and J. Salamon and M. Möddel, and T. Knopp
in: (2019).
Volume: <strong>10953</strong>. Number:
on pages: 426 -- 431
Editor: In Barjor Gimi and Andrzej Krol (Eds.)
Publisher: SPIE:
how published:
Organization: International Society for Optics and Photonics
DOI: 10.1117/12.2512442


Note: inproceedings, interventional

Abstract: Magnetic particle imaging (MPI) is a relatively young, radiation-free imaging modality that measures the interaction between superparamagnetic nanoparticles and magnetic fields. Compared to standard imaging modalities, a key feature of MPI is its ability to measure 3D volumes of relatively high spatial resolution in real-time, while still maintaining high sensitivity. Therefore, MPI is considered promising especially for vascular imaging and interventions. Yet, to fully take advantage of the unique MPI properties, real-time 4D imaging has to be combined with appropriate real-time 4D visualization and image analysis techniques. The current work aims at identification of respective clinical use cases and scenarios to illustrate the potential of MPI in the context of vascular imaging and interventions; the implementation and exploration of suitable visualization and image analysis techniques; and evaluation and comparison of the resulting image data to standard clinical imaging approaches. The study is based on three clinical use cases and associated anatomical sites: mechanical thrombectomy (anatomical structure: middle cerebral artery, segments M1 and M2); endovascular coiling (internal carotid artery aneurysm); and chemoembolization (proper hepatic artery). Implemented visualization and image analysis options are based on direct volume rendering and cover aspects like optimal view point and view angle selection and application of cut-away views. We illustrate that combining MPI imaging and 4D visualization helps to improve vascular image interpretation.