IBI: Niklas Hackelberg

Niklas Hackelberg, M.Sc.

Fraunhofer-Einrichtung für Individualisierte und Zellbasierte Medizintechnik IMTE
Mönkhofer Weg 239a
23562 Lübeck
- Postanschrift -

Technische Universität Hamburg (TUHH)
Institut für Biomedizinische Bildgebung
Gebäude E, Raum 4.044
Am Schwarzenberg-Campus 3
21073 Hamburg

E-Mail: niklas.hackelberg(at)imte.fraunhofer.de
E-Mail: niklas.hackelberg(at)tuhh.de
ORCID: https://orcid.org/0000-0002-0976-9049

Research Interests

Magnetic Particle Imaging
Image reconstruction in MPI, MRI and CT
Parallel computing in Julia

Curriculum Vitae

Niklas Hackelberg is a PhD student in the group of Tobias Knopp for Biomedical Imaging at the University Medical Center Hamburg-Eppendorf and the Hamburg University of Technology. In addition, he works as a software engineer at the Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering IMTE in Lübeck. He studied Computer Science at the Technical University of Hamburg from 2014 to 2021, where he earned his Master's degree with a thesis on "Development of a Scalable and Real-Time Capable Data Acquisition System for Magnetic Particle Imaging."

Journal Publications

132
Tsanda, A.; Reiss, S.; Scheffler, K.; Boberg, M.; Knopp, T.
Deep learning for restoring MPI system matrices using simulated training data
2026 Article Physics in Medicine and Biology
Journal Physics in Medicine and Biology, 71 (9)
DOI:
10.1088/1361-6560/ae6016
131
Foerger, F.; Boberg, M.; Hackelberg, N.; Heinisch, P.; Ostaszewski, K.; Faltinath, J.; Suskin, P.; Thieben, F.; Mohn, F.; Jürß, P.; Möddel, M.; Knopp, T.
3-D Magnetic Field Camera With Subsecond Temporal Resolution
2026 Article IEEE Sensors Journal
Journal IEEE Sensors Journal, 26 (1)
DOI:
10.1109/JSEN.2025.3629803
130
Backes, J.; Tsanda, A.; Knopp, T.; Renz, W.; Schöll, E.
Combining machine learning and physiological network models for sepsis prediction
2026 Article Frontiers in Network Physiology
Journal Frontiers in Network Physiology, 6
DOI:
10.3389/fnetp.2026.1852577
129
Merbach, T.; Adrian, M.; Wigger, C.; Iraqi Houssaini, S.; Bayer, B.; Tsanda, A.; Acikgöz, S.; Weiland, C.; Kexel, F.; Herzog, D.; Hoffmann, M.; Kelbassa, I.; Knopp, T.; Penn, A.; Schlüter, M.
Comprehensive study of 3D liquid flow fields in additively manufactured structures for SMART reactors using large-scale vertical magnetic resonance imaging and computational fluid dynamics
2026 Article Chemical Engineering Journal
Journal Chemical Engineering Journal, 539 : 176536
DOI:
10.1016/j.cej.2026.176536
128
Adrian, M.; Eckert, K. M.; Serial, M. R.; Tsanda, A.; Rennpferdt, L.; Benders, S.; Trieu, H. K.; Knopp, T.; Smirnova, I.; Penn, A.
NMR relaxometry probes solvent-polarity-dependent molecular interactions in stimuli-responsive lyogels
2026 Article Physical Chemistry Chemical Physics
Journal Physical Chemistry Chemical Physics, 28 : 1645-1654
Publisher The Royal Society of Chemistry
DOI:
10.1039/D5CP04032A
127
Dora, J.; Möddel, M.; Flenner, S.; Reimers, J.; Zeller-Plumhoff, B.; Schroer, C. G.; Knopp, T.; Hagemann, J.
Model-based autofocus for near-field phase retrieval
2025 Article Optics Express
Journal Optics Express, 33 (4): 6641-6657
Publisher Optica Publishing Group
DOI:
10.1364/OE.544573
126
Faltinath, J.; Mohn, F.; Foerger, F.; Möddel, M.; Knopp, T.
Natural Frequency Dependence of Magneto-Mechanical Resonators on Magnet Distance
2025 Article IEEE Sensors Journal
Journal IEEE Sensors Journal, 25 (20): 38073-38081
DOI:
10.1109/JSEN.2025.3600007
125
Merbach, T.; Kexel, F.; Faltinath, J.; Möddel, M.; Schlüter, M.; Knopp, T.; Mohn, F.
Wireless and passive pressure detection using magneto-mechanical resonances in process engineering
2025 Article Measurement Science and Technology
Journal Measurement Science and Technology, 36 (8): 085109
DOI:
10.1088/1361-6501/adf2c8
124
Scheffler, K.; Meyn, L.; Foerger, F.; Boberg, M.; Möddel, M.; Knopp, T.
Efficient measurement and representation of magnetic fields in tomographic imaging using ellipsoidal harmonics
2025 Article Communications Physics
Journal Communications Physics, 8 (112)
Publisher Nature
DOI:
10.1038/s42005-025-02012-5
123
Boberg, M.; Knopp, T.; Möddel, M.
Unique compact representation of magnetic fields using truncated solid harmonic expansions
2025 Article European Journal of Applied Mathematics
Journal European Journal of Applied Mathematics : 1-28
DOI:
10.1017/S0956792524000883
122
Tsanda, A.; Nickisch, H.; Wissel, T.; Klinder, T.; Knopp, T.; Grass, M.
Dose robustness of deep learning models for anatomic segmentation of computed tomography images
2024 Article Journal of Medical Imaging
Journal Journal of Medical Imaging, 11 (4): 044005
Publisher SPIE
DOI:
10.1117/1.JMI.11.4.044005
121
Foerger, F.; Boberg, M.; Faltinath, J.; Knopp, T.; Möddel, M.
Design and Optimization of a Magnetic Field Generator for Magnetic Particle Imaging with Soft Magnetic Materials
2024 Article Advanced Intelligent Systems
Journal Advanced Intelligent Systems, 6 (11)
DOI:
10.1002/aisy.202400017
120
Mohn, F.; Foerger, F.; Thieben, F.; Möddel, M.; Schmale, I.; Knopp, T.; Graeser, M.
Resonant Inductive Coupling Network for Human-Sized Magnetic Particle Imaging
2024 Article Review of Scientific Instruments
Journal Review of Scientific Instruments, 95 (4): 044701
DOI:
10.1063/5.0192784
119
Mohn, F.; Scheffler, K.; Ackers, J.; Weimer, A.; Wegner, F.; Thieben, F.; Ahlborg, M.; Vogel, P.; Graeser, M.; Knopp, T.
Characterization of the Clinically Approved MRI Tracer Resotran for Magnetic Particle Imaging in a Comparison Study
2024 Article Physics in Medicine and Biology
Journal Physics in Medicine and Biology, 69 (13): 135014
DOI:
10.1088/1361-6560/ad5828
118
Orsi, F.; Sauerwein, N.; Bhatt, R. P.; Faltinath, J.; Fedotova, E.; Reiter, N.; Cantat-Moltrecht, T.; Brantut, J.-P.
Cavity Microscope for Micrometer-Scale Control of Atom-Photon Interactions
2024 Article PRX Quantum
Journal PRX Quantum, 5 (4): 040333
DOI:
10.1103/PRXQuantum.5.040333
117
Thieben, F.; Foerger, F.; Mohn, F.; Hackelberg, N.; Boberg, M.; Scheel, J.-P.; Möddel, M.; Graeser, M.; Knopp, T.
System Characterization of a Human-Sized 3D Real-Time Magnetic Particle Imaging Scanner for Cerebral Applications
2024 Article Communications Engineering
Journal Communications Engineering, 3 (1): 47
DOI:
10.1038/s44172-024-00192-6
116
Dora, J.; Möddel, M.; Flenner, S.; Schroer, C. G.; Knopp, T.; Hagemann, J.
Artifact-suppressing reconstruction of strongly interacting objects in X-ray near-field holography without a spatial support constraint
2024 Article Optics Express
Journal Optics Express, 32 (7): 10801-10828
Publisher Optica Publishing Group
DOI:
10.1364/OE.514641
115
Scheffler, K.; Boberg, M.; Knopp, T.
Solving the MPI reconstruction problem with automatically tuned regularization parameters
2024 Article Physics in Medicine and Biology
Journal Physics in Medicine and Biology, 69 (4)
DOI:
10.1088/1361-6560/ad2231
114
Nawwas, L.; Möddel, M.; Knopp, T.
Analysis of leakage artifacts and their impact on convergence of algebraic reconstruction in multi-contrast magnetic particle imaging
2024 Article Physics in Medicine and Biology
Journal Physics in Medicine and Biology, 69 (21): 1-15
DOI:
10.1088/1361-6560/ad7e77
113
Maass, M.; Kluth, T.; Droigk, C.; Albers, H.; Scheffler, K.; Mertins, A.; Knopp, T.
Equilibrium Model With Anisotropy for Model-Based Reconstruction in Magnetic Particle Imaging
2024 Article IEEE Transactions on Computational Imaging
Journal IEEE Transactions on Computational Imaging, 10 : 1588 - 1601
DOI:
10.1109/TCI.2024.3490381

Conference Proceedings

247
Schumacher, J.; Tsanda, A.; Römer, P.; Hackelberg, N.; Knopp, T.
A Model-Based Reconstruction Approach to Field-Free Line Magnetic Particle Imaging
2026 Contribution to Proceeding In "2026 IEEE 23rd International Symposium on Biomedical Imaging (ISBI)"
Booktitle 2026 IEEE 23rd International Symposium on Biomedical Imaging (ISBI), Page 1-4
DOI:
10.1109/ISBI61048.2026.11515299
246
Hackelberg, N.; Ackers, J.; Mohn, F.; Graeser, M.; Knopp, T.
Software Implementation of Greedy Optimized MPS Sequences
2025 Contribution to Proceeding In "14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)"
Booktitle , 14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)Volume11, Page 1-2
DOI:
10.18416/IJMPI.2025.2503043
245
Hackelberg, N.; Boberg, M.; Knopp, T.
GPU Accelerated Multi-Patch Reconstruction
2025 Contribution to Proceeding In "14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)"
Booktitle , 14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)Volume11, Page 1-2
DOI:
10.18416/IJMPI.2025.2503048
244
Tsanda, A.; Scheffler, K.; Reiss, S.; Knopp, T.
Denoising the system matrix with deep neural networks for better MPI reconstructions
2025 Contribution to Proceeding In "14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)"
Booktitle , 14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)Volume11
March 2025
DOI:
10.18416/IJMPI.2025.2503047
243
Jürß, P.; Droigk, C.; Boberg, M.; Knopp, T.
TrainingPhantoms.jl: Simple and Versatile Image Phantom Generation
2025 Contribution to Proceeding In "14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)"
Booktitle , 14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)Volume11, Page 1-2
March 2025
DOI:
10.18416/IJMPI.2025.2503031
242
Jürß, P.; Knopp, T.; Busse, B.; von Brackel, F. N.; Boberg, M.
Optimization-based motion estimation in HR-pQCT
2025 Contribution to Proceeding In "IEEE International Symposium on Biomedical Imaging (ISBI 2025)"
Booktitle IEEE International Symposium on Biomedical Imaging (ISBI 2025), Page 1-4
IEEE
DOI:
10.1109/ISBI60581.2025.10981281
241
Tsanda, A.; Benders, S.; Adrian, M.; Penn, A.; Knopp, T.
Chemically Resolved MRI with Field Inhomogeneity Correction
2025 Contribution to Proceeding In "Proceedings of the 18th International Conference on Magnetic Resonance Microscopy (ICMRM)"
Booktitle Proceedings of the 18th International Conference on Magnetic Resonance Microscopy (ICMRM)
File:
https://www.icmrm.org/static/websites/ICMRM_18_Wuerzburg__archived/proceedings/18thICMRM_P-27_Tsanda.pdf
240
Tsanda, A.; Khalid, S.; Möddel, M.; Knopp, T.
Neural implicit representations for grid-agnostic MPI reconstructions
2025 Contribution to Proceeding In "14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)"
Booktitle , 14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)Volume11
March 2025
DOI:
10.18416/IJMPI.2025.2503058
239
Suskin, P.; Foerger, F.; Jürß, P.; Boberg, M.; Knopp, T.; Möddel, M.
Power-Efficient Control of Non-LinearMagnetic Field Generators for MPI
2025 Contribution to Proceeding In "14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)"
Booktitle , 14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)Volume11, Page 1-2
DOI:
10.18416/IJMPI.2025.2503023
238
Durán, D.; Scheffler, K.; Möddel, M.; Knopp, T.
Efficient Iterative Reconstruction for an MPI Equilibrium Model with Anisotropy
2025 Contribution to Proceeding In "14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)"
Booktitle , 14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)Volume11, Page 1-2
DOI:
10.18416/IJMPI.2025.2503015
237
Foerger, F.; Jürß, P.; Boberg, M.; Hau, T.; Knopp, T.; Möddel, M.
Current-to-Field Prediction for Non-Linear Magnetic Systems via Neural Networks
2025 Contribution to Proceeding In "14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)"
Booktitle , 14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)Volume11, Page 1-2
March 2025
DOI:
10.18416/IJMPI.2025.2503009
236
Foerger, F.; Suskin, P.; Boberg, M.; Faltinath, J.; Knopp, T.; Möddel, M.
Uncertainties of a Spherical Magnetic Field Camera
2025 Contribution to Proceeding In "2025 IEEE SENSORS"
Booktitle 2025 IEEE SENSORS, Page 1-4
DOI:
10.1109/SENSORS59705.2025.11331079
235
Reiss, S.; Thieben, F.; Faltinath, J.; Knopp, T.; Boberg, M.
Model-Based Reconstruction in MPI accounting for Field Imperfections
2025 Contribution to Proceeding In "14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)"
Booktitle , 14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)Volume11, Page 1-2
DOI:
10.18416/IJMPI.2025.2503039
234
Faltinath, J.; Schmitz, M.; Foerger, F.; Möddel, M.; Knopp, T.
Simulating Gadolinium-Induced Magnetic Field Variations for Temperature Sensing with Magneto-Mechanical Resonators
2025 Contribution to Proceeding In "2025 IEEE SENSORS"
Booktitle 2025 IEEE SENSORS, Page 1-4
DOI:
10.1109/SENSORS59705.2025.11331063
233
Scheffler, K.; Foerger, F.; Knopp, T.
Experimental Study on Efficient Field Measurement using Ellipsoidal Harmonics
2025 Contribution to Proceeding In "14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)"
Booktitle , 14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)Volume11, Page 1-2
DOI:
10.18416/IJMPI.2025.2503040
232
Nawwas, L.; Möddel, M.; Knopp, T.
Multi-Contrast MPI Matrix Compression
2025 Contribution to Proceeding In "14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)"
Booktitle , 14th International Workshop on Magnetic Particle Imaging (IWMPI 2025)Volume11, Page 1-2
March 2025
DOI:
10.18416/IJMPI.2025.2503062
231
Möddel, M.; Jensen, L.; Boberg, M.; Knopp, T.
Comparison of Reconstruction Methods for Elongated Multi-Patch Sequences in Magnetic Particle Imaging
2024 Contribution to Proceeding In "13th International Workshop on Magnetic Particle Imaging (IWMPI 2024)"
Booktitle , 13th International Workshop on Magnetic Particle Imaging (IWMPI 2024)Volume10, Page 1-1
230
Tsanda, A.; Nickisch, H.; Wissel, T.; Klinder, T.; Knopp, T.; Grass, M.
Learning CT Segmentation from Label Masks Only
2024 Contribution to Proceeding In "Medical Imaging with Deep Learning"
Booktitle Medical Imaging with Deep Learning
File:
https://openreview.net/forum?id=u6pyk0RIpL
229
Hackelberg, N.; Grosser, M.; Tsanda, A.; Mohn, F.; Scheffler, K.; Möddel, M.; Knopp, T.
RegularizedLeastSquares.jl: Modality Agnostic Julia Package for Solving Regularized Least Squares Problems
2024 Contribution to Proceeding In "13th International Workshop on Magnetic Particle Imaging (IWMPI 2024)"
Booktitle , 13th International Workshop on Magnetic Particle Imaging (IWMPI 2024)Volume10, Page 1-4
DOI:
10.18416/IJMPI.2024.2403028
228
Tsanda, A.; Nickisch, H.; Wissel, T.; Klinder, T.; Knopp, T.; Grass, M.
On TotalSegmentator's performance on low-dose CT images
2024 Contribution to Proceeding In "Medical Imaging 2024: Image Processing"
Booktitle In Olivier Colliot and Jhimli Mitra, Editor, Medical Imaging 2024: Image ProcessingVolume12926, Page 86—89
International Society for Optics and Photonics
Editor Olivier Colliot and Jhimli Mitra
Publisher SPIE
DOI:
10.1117/12.3000186

TU Hamburg

Institute for Biomedical Imaging

Lottestraße 55, 2nd floor

22529 Hamburg