Journal Publications
| [191086] |
| Title: In Vitro Detection of Gastrointestinal Bleeding Using Single- and Multi-Contrast MPI. |
| Written by: F. Mohn, P. Szwargulski, M. G. Kaul, M. Graeser, T. Mummert, K. M. Krishnan, T. Knopp, G. Adam, J. Salamon and C. Riedel |
| in: (2024). |
| Volume: <strong>10</strong>. Number: (1 Suppl 1), |
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| DOI: 10.18416/IJMPI.2024.2403031 |
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Note: inproceedings, application
Abstract: Gastrointestinal (GI) bleeding is a potentially life-threatening condition that is typically diagnosed using radiation based imaging modalities such as computed tomography (CT) or catheter-based angiography. Magnetic Particle Imaging (MPI) could provide non-invasive, real-time volumetric imaging without ionizing radiation in future human-sized scanners that covers the entire GI tract. We have developed a human-sized (3D printed) phantom that represents both the bowel lumen and the vascular compartment of the bowel wall. One version has a perforation between the two compartments and a control phantom does not. For single contrast MPI, we evaluate the fluid exchange between the two lumen by observing an administered blood pool tracer. For multi-contrast MPI, the intestinal lumen was filled with an intestinal tracer, which represents an orally administered tracer, to allow co-registration of both tracers at the same location. Both single- and multi-contrast MPI are feasible to visualize GI bleeding and MPI may prove to be a useful tool for radiation-free detection of bleeding throughout the GI tract.
Conference Proceedings
| [191086] |
| Title: In Vitro Detection of Gastrointestinal Bleeding Using Single- and Multi-Contrast MPI. |
| Written by: F. Mohn, P. Szwargulski, M. G. Kaul, M. Graeser, T. Mummert, K. M. Krishnan, T. Knopp, G. Adam, J. Salamon and C. Riedel |
| in: (2024). |
| Volume: <strong>10</strong>. Number: (1 Suppl 1), |
| on pages: |
| Chapter: |
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| Publisher: [object Object]: |
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| how published: |
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| DOI: 10.18416/IJMPI.2024.2403031 |
| URL: |
| ARXIVID: |
| PMID: |
Note: inproceedings, application
Abstract: Gastrointestinal (GI) bleeding is a potentially life-threatening condition that is typically diagnosed using radiation based imaging modalities such as computed tomography (CT) or catheter-based angiography. Magnetic Particle Imaging (MPI) could provide non-invasive, real-time volumetric imaging without ionizing radiation in future human-sized scanners that covers the entire GI tract. We have developed a human-sized (3D printed) phantom that represents both the bowel lumen and the vascular compartment of the bowel wall. One version has a perforation between the two compartments and a control phantom does not. For single contrast MPI, we evaluate the fluid exchange between the two lumen by observing an administered blood pool tracer. For multi-contrast MPI, the intestinal lumen was filled with an intestinal tracer, which represents an orally administered tracer, to allow co-registration of both tracers at the same location. Both single- and multi-contrast MPI are feasible to visualize GI bleeding and MPI may prove to be a useful tool for radiation-free detection of bleeding throughout the GI tract.
