Dr.-Ing. Matthias Gräser

Universitätsklinikum Hamburg-Eppendorf (UKE)
Sektion für Biomedizinische Bildgebung
Lottestraße 55
2ter Stock, Raum 212
22529 Hamburg

Technische Universität Hamburg (TUHH)
Institut für Biomedizinische Bildgebung
Gebäude E, Raum 4.044
Am Schwarzenberg-Campus 3
21073 Hamburg

Tel.: 040 / 7410 25812
E-Mail: matthias.graeser(at)tuhh.de
E-Mail: ma.graeser(at)uke.de

Research Interests

  • Magnetic Particle Imaging
  • Low Noise Electronics
  • Inductive Sensors
  • Passive Electrical Devices

Curriculum Vitae

Matthias Gräser submitted his Dr.-Ing. thesis in january 2016 at the institute of medical engineering (IMT) at the university of Lübeck and is now working as a Research Scientist at the institute for biomedical imaging (IBI) at the technical university in Hamburg, Germany.  Here he develops concepts for Magnetic-Particle-Imaging (MPI) devices. His main aim is to improve the sensitivity of the imageing devices and improve resolution and application possibilities of MPI technology.

In 2011 Matthias Gräser started to work at the IMT as a Research Associate in the Magnetic Particle Imaging Technology (MAPIT) project. In this project he devolped the analog signal chains for a rabbit sized field free line imager. Additionally he developed a two-dimensional Magnetic-Particle-Spectrometer. This device can apply various field sequences and measure the particle response with a very high signal-to-noise ratio (SNR).

The dynamic behaviour of magnetic nanoparticles is still not fully understood. Matthias Gräser investigated the particle behaviour by modeling the particle behaviour with stochastic differential equations. With this model it is possible to simulate the impact of several particle parameters and field sequences on the particle response .

In 2010 Matthias Gräser finished his diploma at the Karlsruhe Institue of Technology (KIT). His diploma thesis investigated the nerve stimulation of magnetic fields in the range from 4 kHz to 25 kHz.

Journal Publications

[76919]
Title: Visualization of instruments in interventional {Magnetic Particle Imaging} ({i{MPI}}): A simulation study on {SPIO} labelings. <em>{Magnetic Particle Imaging}</em>
Written by: H. Wojtczyk, J. Haegele, M. Grüttner, W. Tenner, G. Bringout, M. Graeser, F. M. Vogt, J. Barkhausen, and T. M. Buzug
in: <em>Springer Proceedings in Physics</em>. (2012).
Volume: Number: (140),
on pages: 167--172
Chapter:
Editor:
Publisher: Heidelberg:
Series:
Address:
Edition:
ISBN: 978-3-642-24132-1 978-3-642-24133-8
how published:
Organization:
School:
Institution:
Type:
DOI: 10.1007/978-3-642-24133-8_27s
URL: http://link.springer.com/chapter/10.1007/978-3-642-24133-8_27
ARXIVID:
PMID:

[www] [BibTex]

Note: inproceedings

Abstract: Due to its ability for quantitative 3D real time imaging with high sensitivity and spatial resolution but without ionizing radiation and iodine-based contrast agents, {Magnetic Particle Imaging} shows great promise for the application to the image guidance of cardiovascular interventions. For this purpose, the blood in the vessels and the instruments would have to be visualized, e.g. using a {SPIO}-based contrast agent and a {SPIO} labeling, respectively ({SPIO}: superparamagnetic iron oxide). In a simulation study of this situation, simple models of a guide wire and a catheter with a coated tip as well as a filled balloon catheter have been examined under a variety of conditions. The appearance of the instruments in the reconstructed images has been shown to be strongly dependent on the imaging parameters (gradient strength), the difference of the {SPIO} concentrations in adjacent structures as well as the geometric extensions of the instrument and its position inside the vessel (partial volume effect). It has been demonstrated that the visualization of instruments in a vessel may be possible with positive or negative contrast, depending on the individual circumstances.

Conference Proceedings

[76919]
Title: Visualization of instruments in interventional {Magnetic Particle Imaging} ({i{MPI}}): A simulation study on {SPIO} labelings. <em>{Magnetic Particle Imaging}</em>
Written by: H. Wojtczyk, J. Haegele, M. Grüttner, W. Tenner, G. Bringout, M. Graeser, F. M. Vogt, J. Barkhausen, and T. M. Buzug
in: <em>Springer Proceedings in Physics</em>. (2012).
Volume: Number: (140),
on pages: 167--172
Chapter:
Editor:
Publisher: Heidelberg:
Series:
Address:
Edition:
ISBN: 978-3-642-24132-1 978-3-642-24133-8
how published:
Organization:
School:
Institution:
Type:
DOI: 10.1007/978-3-642-24133-8_27s
URL: http://link.springer.com/chapter/10.1007/978-3-642-24133-8_27
ARXIVID:
PMID:

[www] [BibTex]

Note: inproceedings

Abstract: Due to its ability for quantitative 3D real time imaging with high sensitivity and spatial resolution but without ionizing radiation and iodine-based contrast agents, {Magnetic Particle Imaging} shows great promise for the application to the image guidance of cardiovascular interventions. For this purpose, the blood in the vessels and the instruments would have to be visualized, e.g. using a {SPIO}-based contrast agent and a {SPIO} labeling, respectively ({SPIO}: superparamagnetic iron oxide). In a simulation study of this situation, simple models of a guide wire and a catheter with a coated tip as well as a filled balloon catheter have been examined under a variety of conditions. The appearance of the instruments in the reconstructed images has been shown to be strongly dependent on the imaging parameters (gradient strength), the difference of the {SPIO} concentrations in adjacent structures as well as the geometric extensions of the instrument and its position inside the vessel (partial volume effect). It has been demonstrated that the visualization of instruments in a vessel may be possible with positive or negative contrast, depending on the individual circumstances.