Konrad Scheffler, M.Sc.

Universitätsklinikum Hamburg-Eppendorf (UKE)
Sektion für Biomedizinische Bildgebung
Lottestraße 55
2ter Stock, Raum 213
22529 Hamburg
- Postanschrift -

Technische Universität Hamburg (TUHH)
Institut für Biomedizinische Bildgebung
Gebäude E, Raum 4.044
Am Schwarzenberg-Campus 3
21073 Hamburg

Tel.: 040 / 7410 25813
E-Mail: konrad.scheffler(at)tuhh.de
E-Mail: ko.scheffler(at)uke.de

Research Interests

  • Magnetic Particle Imaging
  • Image Reconstruction

Curriculum Vitae

Konrad Scheffler is a PhD student in the group of Tobias Knopp for Biomedical Imaging at the University Medical Center Hamburg-Eppendorf and the Hamburg University of Technology. He studied Technomathematics between 2015 and 2021 in Hamburg and graduated with a master's degree thesis on "Enhancing matrix compression using convoluted tensor products of Chebyshev polynomials".

Journal Publications

[190507]
Title: Solving the MPI reconstruction problem with automatically tuned regularization parameters.
Written by: K. Scheffler, M. Boberg, and T. Knopp
in: <em>Phys. Med. Biol.</em>. January (2024).
Volume: <strong>69</strong>. Number: (4),
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DOI: 10.1088/1361-6560/ad2231
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Note: article, openaccess

Abstract: In the field of medical imaging, Magnetic Particle Imaging (MPI) poses a promising non-ionizing tomographic technique with high spatial and temporal resolution. In MPI, iterative solvers are used to reconstruct the particle distribution out of the measured voltage signal based on a system matrix. The amount of regularization needed to reconstruct an image of good quality differs from measurement to measurement, depending on the MPI system and the measurement settings. Finding the right choice for the three major parameters controlling the regularization is commonly done by hand and requires time and experience. In this work, we study the reduction to a single regularization parameter and propose a method that enables automatic reconstruction. The method is qualitatively and quantitatively validated on several MPI data sets showing promising results.

Conference Publications

[190507]
Title: Solving the MPI reconstruction problem with automatically tuned regularization parameters.
Written by: K. Scheffler, M. Boberg, and T. Knopp
in: <em>Phys. Med. Biol.</em>. January (2024).
Volume: <strong>69</strong>. Number: (4),
on pages:
Chapter:
Editor:
Publisher:
Series:
Address:
Edition:
ISBN:
how published:
Organization:
School:
Institution:
Type:
DOI: 10.1088/1361-6560/ad2231
URL:
ARXIVID:
PMID:

Note: article, openaccess

Abstract: In the field of medical imaging, Magnetic Particle Imaging (MPI) poses a promising non-ionizing tomographic technique with high spatial and temporal resolution. In MPI, iterative solvers are used to reconstruct the particle distribution out of the measured voltage signal based on a system matrix. The amount of regularization needed to reconstruct an image of good quality differs from measurement to measurement, depending on the MPI system and the measurement settings. Finding the right choice for the three major parameters controlling the regularization is commonly done by hand and requires time and experience. In this work, we study the reduction to a single regularization parameter and propose a method that enables automatic reconstruction. The method is qualitatively and quantitatively validated on several MPI data sets showing promising results.