Florian Thieben, M.Sc.

Universitätsklinikum Hamburg-Eppendorf (UKE)
Sektion für Biomedizinische Bildgebung
Lottestraße 55
2ter Stock, Raum 202
22529 Hamburg
- Postanschrift -

Technische Universität Hamburg (TUHH)
Institut für Biomedizinische Bildgebung
Gebäude E, Raum 4.044
Am Schwarzenberg-Campus 3
21073 Hamburg

Tel.: 040 / 7410 56355
E-Mail: f.thieben(at)uke.de
E-Mail: florian.thieben(at)tuhh.de
ORCID: https://orcid.org/0000-0002-2890-5288

Research Interests

  • Magnetic Particle Imaging
  • Low noise electronics
  • Inductive sensors and filters
  • Magnetic Particle Imaging scanner characterization

Curriculum Vitae

Florian Thieben is a PhD student in the group of Tobias Knopp for experimental Biomedical Imaging at the University Medical Center Hamburg-Eppendorf and the Hamburg University of Technology. In 2017 he graduated with a master's degree thesis on Entwicklung eines kompakten Magnet Partikel Spektrometers mit gradiometrischer Empfangskette".

Journal Publications

[164769]
Title: Design of a head coil for high resolution mouse brain perfusion imaging using magnetic particle imaging.
Written by: M. Graeser, P. Ludewig, P. Szwargulski, F. Foerger, T. Liebing, N. D. Forkert, F. Thieben, T. Magnus, and T. Knopp
in: <em>Physics in Medicine and Biology</em>. (2020).
Volume: <strong>65</strong>. Number: (23),
on pages: 235007
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DOI: 10.1088/1361-6560/abc09e
URL: https://arxiv.org/abs/2004.11728
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[www]

Note: article, magneticfield

Abstract: Magnetic Particle Imaging (MPI) is a novel and versatile imaging modality developing towards human application. When up-scaling to human size, the sensitivity of the systems naturally drops as the coil sensitivity depends on the bore diameter. Thus, new methods to push the sensitivity limit further have to be investigated to cope for this loss. In this paper a dedicated surface coil improving the sensitvity in cerebral imaging applications was developed. Similar to MRI the developed surface coil improves the sensitivity due to the closer vicinity to the region of interest. With the developed surface coil presented in this work, it is possible to image tracer samples containing only 896 pg iron and detect even small vessels and anatomical structures within a wild type mouse model. As current sensitivity measures are dependent on the tracer system a new method for determining a sensitivity measure without this dependence on the tracer is presented and verified to enable comparison between MPI receiver systems.

Conference Proceedings

[164769]
Title: Design of a head coil for high resolution mouse brain perfusion imaging using magnetic particle imaging.
Written by: M. Graeser, P. Ludewig, P. Szwargulski, F. Foerger, T. Liebing, N. D. Forkert, F. Thieben, T. Magnus, and T. Knopp
in: <em>Physics in Medicine and Biology</em>. (2020).
Volume: <strong>65</strong>. Number: (23),
on pages: 235007
Chapter:
Editor:
Publisher:
Series:
Address:
Edition:
ISBN:
how published:
Organization:
School:
Institution:
Type:
DOI: 10.1088/1361-6560/abc09e
URL: https://arxiv.org/abs/2004.11728
ARXIVID:
PMID:

[www] [BibTex]

Note: article, magneticfield

Abstract: Magnetic Particle Imaging (MPI) is a novel and versatile imaging modality developing towards human application. When up-scaling to human size, the sensitivity of the systems naturally drops as the coil sensitivity depends on the bore diameter. Thus, new methods to push the sensitivity limit further have to be investigated to cope for this loss. In this paper a dedicated surface coil improving the sensitvity in cerebral imaging applications was developed. Similar to MRI the developed surface coil improves the sensitivity due to the closer vicinity to the region of interest. With the developed surface coil presented in this work, it is possible to image tracer samples containing only 896 pg iron and detect even small vessels and anatomical structures within a wild type mouse model. As current sensitivity measures are dependent on the tracer system a new method for determining a sensitivity measure without this dependence on the tracer is presented and verified to enable comparison between MPI receiver systems.