
| [183658] | 
| Title: Safe and Rapid 3D Imaging: Upgrade of a Human-Sized Brain MPI System. | 
| Written by: F. Thieben, F. Mohn, F. Foerger, N. Hackelberg, J.-P. Scheel, M. Graeser, and T. Knopp | 
| in: <em>International Journal on Magnetic Particle Imaging</em>. mar (2023). | 
| Volume: <strong>9</strong>. Number: (1 Suppl 1), | 
| on pages: 1-4 | 
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| DOI: 10.18416/IJMPI.2023.2303045 | 
| URL: https://journal.iwmpi.org/index.php/iwmpi/article/view/611 | 
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Note: inproceedings, brainimager
Abstract: Magnetic Particle Imaging hardware has reached human scale and thus patient safety questions and clinical application scenarios are in the focus of current research. In this work, we present a safe real-time 3D MPI system for cerebral applications. High voltages are avoided to ensure patient safety by a low voltage-high current transmit coil design. The developed 2D drive-field generator generates a field-free-point trajectory in the sagittal xz-plane that is shifted by a dynamic selection-field sequence along the y-axis. The scanner generates 3D images with 4 frames/second and allows for direct visualization of the clinically preferred transversal yz-plane, which is crucial for future brain examinations. Advanced reconstruction techniques reach a system sensitivity of 4 μgFe with respect to the iron mass in a sensitivity study.
| [183658] | 
| Title: Safe and Rapid 3D Imaging: Upgrade of a Human-Sized Brain MPI System. | 
| Written by: F. Thieben, F. Mohn, F. Foerger, N. Hackelberg, J.-P. Scheel, M. Graeser, and T. Knopp | 
| in: <em>International Journal on Magnetic Particle Imaging</em>. mar (2023). | 
| Volume: <strong>9</strong>. Number: (1 Suppl 1), | 
| on pages: 1-4 | 
| Chapter: | 
| Editor: | 
| Publisher: | 
| Series: | 
| Address: | 
| Edition: | 
| ISBN: | 
| how published: | 
| Organization: | 
| School: | 
| Institution: | 
| Type: | 
| DOI: 10.18416/IJMPI.2023.2303045 | 
| URL: https://journal.iwmpi.org/index.php/iwmpi/article/view/611 | 
| ARXIVID: | 
| PMID: | 
Note: inproceedings, brainimager
Abstract: Magnetic Particle Imaging hardware has reached human scale and thus patient safety questions and clinical application scenarios are in the focus of current research. In this work, we present a safe real-time 3D MPI system for cerebral applications. High voltages are avoided to ensure patient safety by a low voltage-high current transmit coil design. The developed 2D drive-field generator generates a field-free-point trajectory in the sagittal xz-plane that is shifted by a dynamic selection-field sequence along the y-axis. The scanner generates 3D images with 4 frames/second and allows for direct visualization of the clinically preferred transversal yz-plane, which is crucial for future brain examinations. Advanced reconstruction techniques reach a system sensitivity of 4 μgFe with respect to the iron mass in a sensitivity study.