Founded in 1986 as one of the first university research institutes in Bioprocess Engineering in Germany, IBB has a long tradition and wide expertise in research and development of bioprocesses using microbial and mammalian cell cultures for the production of chemicals, fuels and biomaterials from renewable resources, and more recently from CO2 and other one-carbon (C1) substrates.
Typically, more than 30 coworkers (mostly PhD, Master and Bachelor students) work in a highly interdisciplinary and international environment in our institute. Our present research interests include (1) Modelling, quantitative analysis and design of novel enzymes (proteins), metabolic pathways and cells using tools of metabolic engineering, systems and synthetic biology; (2) Electrobiotechnology, especially development of novel electrodes and control strategies for smart electro-bioreactor system for the use of CO2, water and electricity for biosynthesis (also called Technical Photosynthesis); (3) Development of protein and cell based new biomaterials for uses in biotechnology and biomedicine. We develop integrated bioproduction systems (e.g. Biorefinery concept) from lab, over miniplant to pilot plant (up to 300 L bioreactor and corresponding downstream processing facility) in our institute and collaborate with industrial partners for their technical realization. Our Molecular and Multiscale Biosystems Engineering approach is demonstrated to be successful in developing several new bioprocesses such as for diols (C3-C5), amino acids (e.g. L-lysine, L- tryptophan and derivatives), organic acidsand protein based hybrid biomaterials.
For teaching we are actively involved in several B.Sc. and M.Sc. programs in General Engineering Science, Process Engineering and Bioprocess Engineering. Following the German tradition in training engineers we emphasize a solid engineering understanding and practical handling. Furthermore, we train a new generation of engineers with a deep quantitative and systemic understanding of cellular and bio-molecular processes.