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 Rebecca Schmitz successfully defended her PhD thesis. Congratulations!
We welcome Ahmed Haddad from Alexandria visiting us for 6 month.  
The course "Advanced Practical Course Bioprocess Engineering" will be held on [...]
Dear colleagues, on Thurday, 9th of August 2018 we will have our IBB outreach to Fischbeker [...]
The experimental course bioprocess engineering will be held on 08. October to 12. October 2018 (Mo [...]

Project Works and Master Theses



CFD-Assisted Characterization of Shear Forces in Bioreactors

Master's thesis, CFD simulation, model validation

contact:Fabian Freiberger
email:fabian.freiberger@tuhh.de
phone:+49 40 42878 3950


Characterization of the Impact of Shear Forces on Mammalian Cell Cultures

Master's thesis, CHO cell cultivation, antibody product quality

contact:Fabian Freiberger
email:fabian.freiberger@tuhh.de
phone:+49 40 42878 3950


Bioconversion of glycerol to 3-Hydroxypropionaldehyd

Entwicklung von Verfahren zur Produktion und Aufarbeitung von 3-Hydroxypropionaldehyd

3HPA-Thesis
Contact:Prof. Dr. An-Ping Zeng
email:aze@tu-harburg.de
phone:+49 40 42878 4183
fax:+49 40 42878 2909


Cell culture technology

Contact:Prof. Dr.-Ing. Ralf Pörtner
email:poertner@tu-harburg.de
phone:+49 40 42878 2886
fax:+49 40 42878 2909

Im Bereich "Zellkulturtechnik" bieten wir in den folgenden Schwerpunkten Themen für Diplomarbeiten an:

Entwicklung von Festbettreaktoren fur die Kultur tierischer Zellen auf makroporösen Trägermaterialien; Einsatzgebiete: Produktion monoklonaler Antikörper, rekombinante adhärente Zellen, physiologische Untersuchungen an Tumorzellen, künstliche Organe (Leber)

Entwicklung von Fütterungsstrategien und modellgestützte Prozessführung für Zellkulturen

Kultivierung von Chondrozyten zur Erstellung eines implantierbaren Gelenkknorpelersatzes "in vitro"


Continuous cultivation of lactic acid bacteria

Contact:Prof. Dr.-Ing. Ralf Pörtner
email:poertner@tu-harburg.de
phone:+49 40 42878 2886
fax:+49 40 42878 2909

There have been numerous studies on the conversion of sugars, including glucose, lactose and sucrose, to lactic acid and valuable secondary metabolites with lactic acid bacteria in different types of processes to achieve higher productivity. The fermentation by conventional methods that use cell suspension in batch processes has several limitations, such as low productivity, product inhibition and also the variation from batch to batch. Cell immobilization techniques have become more important and popular because it gives many advantages compared to cell suspension culture such as maintenance of stable and active biocatalysts, accelerated reaction rates, high volumetric productivity, improved process control, reduced susceptibility of cells to contamination, improved production efficiency and no possibility of washout.

The aim of this project is to optimize the performance of long-term cultures of lactic acid bacteria in a fixed-bed reactor system.