Hao-Hsiang Hsu successfully defended his PhD thesis. Congratulations!
Tyll Utesch successfully defended his PhD thesis. Congratulations!
We welcome our new PhD student Chijian Zhang from China. He got his master's degree and graduated [...]
We are happy to have had four presentations at the Dechema Himmelfahrtstagung 2019. Uwe Jandt [...]
We congratulate our student Lukas Arndt for the winning of a price at the students conference 2019 [...]

Project Works and Master Theses

Bioconversion of glycerol to 3-Hydroxypropionaldehyd

Entwicklung von Verfahren zur Produktion und Aufarbeitung von 3-Hydroxypropionaldehyd

Contact:Prof. Dr. An-Ping Zeng
phone:+49 40 42878 4183
fax:+49 40 42878 2909

Cell culture technology

Contact:Prof. Dr.-Ing. Ralf Pörtner
phone:+49 40 42878 2886
fax:+49 40 42878 2909

Im Bereich "Zellkulturtechnik" bieten wir in den folgenden Schwerpunkten Themen für Diplomarbeiten an:

Entwicklung von Festbettreaktoren fur die Kultur tierischer Zellen auf makroporösen Trägermaterialien; Einsatzgebiete: Produktion monoklonaler Antikörper, rekombinante adhärente Zellen, physiologische Untersuchungen an Tumorzellen, künstliche Organe (Leber)

Entwicklung von Fütterungsstrategien und modellgestützte Prozessführung für Zellkulturen

Kultivierung von Chondrozyten zur Erstellung eines implantierbaren Gelenkknorpelersatzes "in vitro"

Continuous cultivation of lactic acid bacteria

Contact:Prof. Dr.-Ing. Ralf Pörtner
phone:+49 40 42878 2886
fax:+49 40 42878 2909

There have been numerous studies on the conversion of sugars, including glucose, lactose and sucrose, to lactic acid and valuable secondary metabolites with lactic acid bacteria in different types of processes to achieve higher productivity. The fermentation by conventional methods that use cell suspension in batch processes has several limitations, such as low productivity, product inhibition and also the variation from batch to batch. Cell immobilization techniques have become more important and popular because it gives many advantages compared to cell suspension culture such as maintenance of stable and active biocatalysts, accelerated reaction rates, high volumetric productivity, improved process control, reduced susceptibility of cells to contamination, improved production efficiency and no possibility of washout.

The aim of this project is to optimize the performance of long-term cultures of lactic acid bacteria in a fixed-bed reactor system.