Simon Matthes, M.Sc.
Eißendorfer Str. 40, Building N, Room 1.083
Telephone +49 40 42878-3614
E-Mail: Simon Matthes, M.Sc.
Many chemical and biocatalytic reactions are consuming gaseous species like oxygen, provided by the mass transfer across interfaces of multiphase contact apparatuses. In large-scale processes the gas is often supplied to the liquid bulk phase by bubble aeration. Especially for biocatalytic reactions the macroscopic aeration can lead to reduced enzyme activity by foaming and induced shear forces. For fast chemical reactions in multiphase flows, the mass transfer limitation is often the bottleneck for a process optimization. Compared to large-scale bubble aeration, the potential of using bubbles smaller than 100 μm is less explored so far.
At that point this project starts investigating the aeration with fine bubbles, due to the rising demand in process engineering for aeration with high mass transfer performance, low pressure drop, low shear stress and the avoidance of foaming. Bubbles with diameters less than 100 μm offer large volume-specific interfacial areas a and therefore high mass transfer rates βLa of the gaseous reactant on its way to the bulk phase.
Graduate Teaching Assistant
- Fluid Mechanics for Process Engineering
- Application of Fluid Mechanics in Process Engineering
- Transport Precesses including Multiphase Flows and Heat & Mass Transfer
- Problem Based Learning: Reactor Desing using Local Transport Processes
- "Design of a microscale countercurrent flow cell and investigation of concentration fields araound a single oxygen microbubble using confocal Laser scanning Induced Fluorescence (LIF)", Metehan Gürel, Bachelor thesis, 2019
- "Comparison of three different microbubble spargers for STR and investigation of the innfluence of the stripping gas on the mass transfer performance", Anosha Zia, Master thesis, 2019
- "Experimental investigation of the influence of periodic open cell structures (POCS) in microbubble aerated bubble column", H. Doss, Bachelor thesis, 2019
- "Investigation of the shrinking behavior of microscale bubbles and slug flows", Yusuke Noguchi, International guest student, 2019
- "Characterization of the flow field of a half-pipe channel flow using Laser-Doppler-Anemometrie and the investigation of the cleaning effect using ultrafine bubbles for the industrial CIP process", M.Weiß, Master Thesis, 2018
- "Influence of 3D printed periodic open cell structures (POCS) on the behavior of microbubbles", Daniela Eixenberger, Project work, 2018
- "Experimental investigation of the cleaning effect of water containing ultrafine bubbles using laminar film flow", A. Raschdi, Bachelor Thesis, 2018
- "Development of a measurement method differing between gaseous nanoparticles and solids", H. Ishaque, Project work, 2018
- "Investigation of the germination of barley seeds using ultrafine bubble water - UFBeer", R. Sekimizu, International guest student, 2018
- "Investigation of ultrafine bubbles and their potential use for the remove of membrane fouling in Dead-End-Filtration", A. Püschel, Bachelor thesis, 2017
Oral and Poster Presentations
- Matthes, S.; Thomas, B.; Ohde, D.; Bubenheim, P.; Liese, A.; Tanaka, S.; Terasaka, K.; Schlüter, M.: Influence of microbubble aeration on hydrodynamics and mass transfer in a lab scaled Stirred Tank Reactor, 12th European Congress of Chemical Engineering, Florence, Italy 2019, oral presentation.
- Matthes, S.; Thomas, B.; Ohde, D.; Bubenheim, P.; Liese, A.; Terasaka, K.; Schlüter, M.: Influence of microbubble aeration on hydrodynamics and mass transfer in a 3 L Stirred Tank Reactor, ProcessNet Jahrestreffen MPH, Würzburg, Germany, 2019, poster presentation
- Matthes, S.; Kastens, S.; Thomas, B.; Ohde, D.; Bubenheim, P.; Liese, A.; Noguchi, Y.; Terasaka, K.; Schlüter, M.: Experimental analysis of concentration fields around a free rising oxygen microbubble using Laser Induced Fluorescence, 10th International Conference on Multiphase Flow, Rio de Janeiro, Brasil, 2019, oral presentation
- Matthes, S.; Kastens, S.; Thomas, B.; Ohde, D.; Bubenheim, P.; Liese, A.; Tanaka, S.; Terasaka, K.; Schlüter, M.:Characterization of Fine Bubbles for Biocatalytic Processes, 1st Interantional Workshop on the Application of Fine and Ultrafine Bubbles, 2018, oral presentation
- Matthes, S.; Kastens, S.; Thomas, B.; Ohde, D.; Bubenheim, P.; Liese, A.; Tanaka, S.; Terasaka, K.; Schlüter, M.:Characterization of Fine Bubbles for Biocatalytic Processes, 9th International Symposium on the Application of Laser and Imaging Techniques to Fluid Mechanics, Lisbon, Portugal, 2018, oral presentation
- Matthes, S.; Szeliga, N.; Hoffmann, M.; Wegener, M.; Maaß, S. M.; Pesch, S.; Schlüter, M.: Measurement of particle size distribution in liquid-liquid jets for a more reliable scale-up of industrial processes, Achema Congress, Frankfurt, Germany, 2018, oral presentation
- Matthes, S.; Kastens, S.; Thomas, B.; Ohde, D.; Bubenheim, P.; Liese, A.; Tanaka, S.; Terasaka, K.; Schlüter, M.: Fine Bubbles for Biocatalytic Processes, ProcessNet Jahrestreffen MPH, Bremen,Germany, 2018, poster presentation
|Title: Comparative investigation of fine bubble and macrobubble aeration on gas utility and biotransformation productivity|
|Written by: Thomas, B.; Ohde, D.; Matthes, S.; Engelmann, C.; Bubenheim, P.; Terasaka, K.; Schlüter, M.; Liese, A.|
|in: Biotechnology and Bioengineering 2020|
Abstract: The sufficient provision of oxygen is mandatory for enzymatic oxidations in aqueous solution, however, in process optimization this still is a bottleneck that cannot be overcome with the established methods of macrobubble aeration. Providing higher mass transfer performance through microbubble aerators, inefficient aeration can be overcome or improved. Investigating the mass transport performance in a model protein solution, the microbubble aeration results in higher kLa values related to the applied airstream in comparison with macrobubble aeration. Comparing the aerators at identical kLa of 160 and 60 1/h, the microbubble aeration is resulting in 25 and 44 times enhanced gas utility compared with aeration with macrobubbles. To prove the feasibility of microbubbles in biocatalysis, the productivity of a glucose oxidase catalyzed biotransformation is compared with macrobubble aeration as well as the gas-saving potential. In contrast to the expectation that the same productivities are achieved at identically applied kLa, microbubble aeration increased the gluconic acid productivity by 32% and resulted in 41.6 times higher oxygen utilization. The observed advantages of microbubble aeration are based on the large volume-specific interfacial area combined with a prolonged residence time, which results in a high mass transfer performance, less enzyme deactivation by foam formation, and reduced gas consumption. This makes microbubble aerators favorable for application in biocatalysis.