Prof. Dr.-Ing. Tobias Knopp

Universitätsklinikum Hamburg-Eppendorf (UKE)
Sektion für Biomedizinische Bildgebung
Lottestraße 55
2ter Stock, Raum 209
22529 Hamburg
Tel.: 040 / 7410 56794
Fax: 040 / 7410 45811
E-Mail: t.knopp(at)

Technische Universität Hamburg (TUHH)
Institut für Biomedizinische Bildgebung
Gebäude E, Raum 4.044
Am Schwarzenberg-Campus 3
21073 Hamburg
E-Mail: tobias.knopp(at)




  • Head of the Institute for Biomedical Imaging
  • Editor-in-chief of the International Journal on Magnetic Particle Imaging (IJMPI)

Consulting Hours

  • On appointment

Research Interests

  • Tomographic Imaging
  • Image Reconstruction
  • Signal- and Image Processing
  • Magnetic Particle Imaging

Curriculum Vitae

Tobias Knopp received his Diplom degree in computer science in 2007 and his PhD in 2010, both from the University of Lübeck with highest distinction. For his PHD on the tomographic imaging method Magnetic Particle Imaging (MPI) he was awarded with the Klee award from the DGBMT (VDE) in 2011. From 2010 until 2011 he led the MAPIT project at the University of Lübeck and published the first scientific book on MPI. In 2011 he joined Bruker Biospin to work on the first commercially available MPI system. From 2012 until 2014 he worked at Thorlabs in the field of Optical Coherence Tomography (OCT) as a software developer. In 2014 he has been appointed as Professor for experimental Biomedical Imaging at the University Medical Center Hamburg-Eppendorf and the Hamburg University of Technology.


Title: Signal separation in magnetic particle imaging
Written by: M. Graeser, T. Knopp, T. F. Sattel, M. Grüttner, and T. M. Buzug
in: {IEEE} Nuclear Science Symposium and Medical Imaging Conference ({NSS}/{MIC}) 2012
Volume: Number:
on pages: 2483--2485
how published:
DOI: 10.1109/NSSMIC.2012.6551566

[doi] [BibTex]

Note: inproceedings

Abstract: Magnetic particle imaging ({MPI}) applies oscillating magnetic fields to measure the distribution of magnetic nanoparticles in-vivo. Using receive coils, the change of the particle magnetization can be detected. However, the signal induced by the nanoparticles is superimposed by the signal induced by the sinusoidal excitation field, which directly couples into the receive coils. As the latter is several magnitudes higher, the separation of the particle signal from the excitation signal is a challenging task. One way to remove the excitation signal from the induced voltage in the receive coil is to suppress the excitation signal at its base frequency by means of a band-stop filter. An alternative is to recover the particle signal by compensating the excitation signal in the receive chain, which allows recovering the particle signal at its full bandwidth. In this work, it is proposed to combine both methods which allows increasing the dynamic range of the recorded signal while still recovering the fundamental frequency.