Prof. Dr.-Ing. Tobias Knopp

Universitätsklinikum Hamburg-Eppendorf (UKE)
Sektion für Biomedizinische Bildgebung
Lottestraße 55
2ter Stock, Raum 209
22529 Hamburg
Tel.: 040 / 7410 56794
Fax: 040 / 7410 45811
E-Mail: t.knopp(at)uke.de

Technische Universität Hamburg (TUHH)
Institut für Biomedizinische Bildgebung
Gebäude E, Raum 4.044
Am Schwarzenberg-Campus 3
21073 Hamburg
E-Mail: tobias.knopp(at)tuhh.de

 

 

Roles

  • Head of the Institute for Biomedical Imaging
  • Editor-in-chief of the International Journal on Magnetic Particle Imaging (IJMPI)

Consulting Hours

  • On appointment

Research Interests

  • Tomographic Imaging
  • Image Reconstruction
  • Signal- and Image Processing
  • Magnetic Particle Imaging

Curriculum Vitae

Tobias Knopp received his Diplom degree in computer science in 2007 and his PhD in 2010, both from the University of Lübeck with highest distinction. For his PHD on the tomographic imaging method Magnetic Particle Imaging (MPI) he was awarded with the Klee award from the DGBMT (VDE) in 2011. From 2010 until 2011 he led the MAPIT project at the University of Lübeck and published the first scientific book on MPI. In 2011 he joined Bruker Biospin to work on the first commercially available MPI system. From 2012 until 2014 he worked at Thorlabs in the field of Optical Coherence Tomography (OCT) as a software developer. In 2014 he has been appointed as Professor for experimental Biomedical Imaging at the University Medical Center Hamburg-Eppendorf and the Hamburg University of Technology.

Publications

[140966]
Title: Intelligent Chest X-ray Worklist Prioritization by CNNs: A Clinical Workflow Simulation
Written by: I. M. Baltruschat, L. Steinmeister, H. Nickisch, A. Saalbach, M. Grass, G. Adam, H. Ittrich and T. Knopp
in: arXiv January 2020
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Address: https://arxiv.org/abs/2001.08625
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[pdf] [BibTex]

Note: article

Abstract: Growing radiologic workload and shortage of medical experts worldwide often lead to delayed or even unreported examinations, which poses a risk for patient's safety in case of unrecognized findings in chest radiographs (CXR). The aim was to evaluate, whether deep learning algorithms for an intelligent worklist prioritization might optimize the radiology workflow and can reduce report turnaround times (RTAT) for critical findings, instead of reporting according to the First-In-First-Out-Principle (FIFO). Furthermore, we investigated the problem of false negative prediction in the context of worklist prioritization. To assess the potential benefit of an intelligent worklist prioritization, three different workflow simulations based on our analysis were run and RTAT were compared: FIFO (non-prioritized), Prio1 (prioritized) and Prio2 (prioritized, with RTATmax.). Examination triage was performed by "ChestXCheck", a convolutional neural network, classifying eight different pathological findings ranked in descending order of urgency: pneumothorax, pleural effusion, infiltrate, congestion, atelectasis, cardiomegaly, mass and foreign object. The average RTAT for all critical findings was significantly reduced by both Prio simulations compared to the FIFO simulation (e.g. pneumothorax: 32.1 min vs. 69.7 min; p < 0.0001), while the average RTAT for normal examinations increased at the same time (69.5 min vs. 90.0 min; p < 0.0001). Both effects were slightly lower at Prio2 than at Prio1, whereas the maximum RTAT at Prio1 was substantially higher for all classes, due to individual examinations rated false negative.Our Prio2 simulation demonstrated that intelligent worklist prioritization by deep learning algorithms reduces average RTAT for critical findings in chest X-ray while maintaining a similar maximum RTAT as FIFO.