Prof. Dr.-Ing. Tobias Knopp

Universitätsklinikum Hamburg-Eppendorf (UKE)
Sektion für Biomedizinische Bildgebung
Lottestraße 55
2ter Stock, Raum 209
22529 Hamburg
Tel.: 040 / 7410 56794
Fax: 040 / 7410 45811
E-Mail: t.knopp(at)uke.de

Technische Universität Hamburg (TUHH)
Institut für Biomedizinische Bildgebung
Gebäude E, Raum 4.044
Am Schwarzenberg-Campus 3
21073 Hamburg
E-Mail: tobias.knopp(at)tuhh.de

 

 

Roles

  • Head of the Institute for Biomedical Imaging
  • Editor-in-chief of the International Journal on Magnetic Particle Imaging (IJMPI)

Consulting Hours

  • On appointment

Research Interests

  • Tomographic Imaging
  • Image Reconstruction
  • Signal- and Image Processing
  • Magnetic Particle Imaging

Curriculum Vitae

Tobias Knopp received his Diplom degree in computer science in 2007 and his PhD in 2010, both from the University of Lübeck with highest distinction. For his PHD on the tomographic imaging method Magnetic Particle Imaging (MPI) he was awarded with the Klee award from the DGBMT (VDE) in 2011. From 2010 until 2011 he led the MAPIT project at the University of Lübeck and published the first scientific book on MPI. In 2011 he joined Bruker Biospin to work on the first commercially available MPI system. From 2012 until 2014 he worked at Thorlabs in the field of Optical Coherence Tomography (OCT) as a software developer. In 2014 he has been appointed as Professor for experimental Biomedical Imaging at the University Medical Center Hamburg-Eppendorf and the Hamburg University of Technology.

Publications

[134633]
Title: Towards accurate modeling of the multidimensional magnetic particle imaging physics
Written by: T. Kluth, P. Szwargulski, T. Knopp
in: New Journal of Physics 10 2019
Volume: 21 Number: 10
on pages: 103032
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DOI: 10.1088/1367-2630/ab4938
URL: https://doi.org/10.1088%2F1367-2630%2Fab4938
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Note: article

Abstract: The image reconstruction problem of the tomographic imaging technique magnetic particle imaging (MPI) requires the solution of a linear inverse problem. One prerequisite for this task is that the imaging operator that describes the mapping between the tomographic image and the measured signal is accurately known. For 2D and 3D excitation patterns, it is common to measure the system matrix in a calibration procedure, that is both, very time consuming and adds noise to the operator. The need for measuring the system matrix is due to the lack of an accurate model that is capable of describing the nanoparticles’ magnetization behavior in the MPI setup. Within this work we exploit a physical model that is based on Néel rotation for large particle ensembles and we find model parameters that describe measured 2D MPI data with much higher precision than state of the art MPI models. With phantom experiments we show that the simulated system matrix can be used for image reconstruction and reduces artifacts due to model-mismatch considerably.