# Dr.-Ing. Matthias Gräser

Universitätsklinikum Hamburg-Eppendorf (UKE)

Sektion für Biomedizinische Bildgebung

Lottestraße 55

2ter Stock, Raum 212

22529 Hamburg

Technische Universität Hamburg (TUHH)

Institut für Biomedizinische Bildgebung

Gebäude E, Raum 4.044

Am Schwarzenberg-Campus 3

21073 Hamburg

Tel.: 040 / 7410 25812

E-Mail: matthias.graeser(at)tuhh.de

E-Mail: ma.graeser(at)uke.de

# Research Interests

- Magnetic Particle Imaging
- Low Noise Electronics
- Inductive Sensors
- Passive Electrical Devices

# Curriculum Vitae

Matthias Gräser submitted his Dr.-Ing. thesis in january 2016 at the institute of medical engineering (IMT) at the university of Lübeck and is now working as a Research Scientist at the institute for biomedical imaging (IBI) at the technical university in Hamburg, Germany. Here he develops concepts for Magnetic-Particle-Imaging (MPI) devices. His main aim is to improve the sensitivity of the imageing devices and improve resolution and application possibilities of MPI technology.

In 2011 Matthias Gräser started to work at the IMT as a Research Associate in the *Magnetic Particle Imaging Technology (MAPIT)* project. In this project he devolped the analog signal chains for a rabbit sized field free line imager. Additionally he developed a two-dimensional Magnetic-Particle-Spectrometer. This device can apply various field sequences and measure the particle response with a very high signal-to-noise ratio (SNR).

The dynamic behaviour of magnetic nanoparticles is still not fully understood. Matthias Gräser investigated the particle behaviour by modeling the particle behaviour with stochastic differential equations. With this model it is possible to simulate the impact of several particle parameters and field sequences on the particle response .

In 2010 Matthias Gräser finished his diploma at the Karlsruhe Institue of Technology (KIT). His diploma thesis investigated the nerve stimulation of magnetic fields in the range from 4 kHz to 25 kHz.

# Journal Publications

[76893] |

Title: 1D-image reconstruction for magnetic particle imaging using a hybrid system function. |

Written by: M. Grüttner, M. Graeser, S. Biederer, T. F. Sattel, H. Wojtczyk, W. Tenner, T. Knopp, B. Gleich, J. Borgert, and T. M. Buzug |

in: <em>{IEEE} Nuclear Science Symposium and Medical Imaging Conference ({NSS}/{MIC})</em>. (2011). |

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DOI: 10.1109/NSSMIC.2011.6152687 |

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**Note: **inproceedings

**Abstract: **{Magnetic Particle Imaging} is a promising imaging technique using iron-oxide nanoparticle tracers. The spatial distribution of these particles can be determined by solving a system of linear equations. This reconstruction is based on a system function that either has to be measured or can be calculated with given information about scanner topology and particle characteristics. This paper introduces a new approach combining both possibilities. A Magnetic Particle Spectrometer is used to obtain a hybrid system function. Furthermore, we will show that the hybrid system function can be successfully used for 1D-image reconstruction and potentially is an alternative to the measurement-based system function.

# Conference Proceedings

[76893] |

Title: 1D-image reconstruction for magnetic particle imaging using a hybrid system function. |

Written by: M. Grüttner, M. Graeser, S. Biederer, T. F. Sattel, H. Wojtczyk, W. Tenner, T. Knopp, B. Gleich, J. Borgert, and T. M. Buzug |

in: <em>{IEEE} Nuclear Science Symposium and Medical Imaging Conference ({NSS}/{MIC})</em>. (2011). |

Volume: Number: |

on pages: 2545--2548 |

Chapter: |

Editor: |

Publisher: |

Series: |

Address: |

Edition: |

ISBN: |

how published: |

Organization: |

School: |

Institution: |

Type: |

DOI: 10.1109/NSSMIC.2011.6152687 |

URL: |

ARXIVID: |

PMID: |

**Note: **inproceedings

**Abstract: **{Magnetic Particle Imaging} is a promising imaging technique using iron-oxide nanoparticle tracers. The spatial distribution of these particles can be determined by solving a system of linear equations. This reconstruction is based on a system function that either has to be measured or can be calculated with given information about scanner topology and particle characteristics. This paper introduces a new approach combining both possibilities. A Magnetic Particle Spectrometer is used to obtain a hybrid system function. Furthermore, we will show that the hybrid system function can be successfully used for 1D-image reconstruction and potentially is an alternative to the measurement-based system function.