Dr.-Ing. Konrad Scheffler

Portrait of Konrad Scheffler

Universitätsklinikum Hamburg-Eppendorf (UKE)
Sektion für Biomedizinische Bildgebung
Lottestraße 55
2ter Stock, Raum 213
22529 Hamburg
- Postanschrift -

Technische Universität Hamburg (TUHH)
Institut für Biomedizinische Bildgebung
Gebäude E, Raum 4.044
Am Schwarzenberg-Campus 3
21073 Hamburg

Tel.: 040 / 7410 25813
E-Mail: konrad.scheffler(at)tuhh.de
E-Mail: ko.scheffler(at)uke.de

Research Interests

  • Magnetic Particle Imaging
  • Image Reconstruction
  • Image Processing

Curriculum Vitae

Konrad Scheffler studied Technomathematics between 2015 and 2021 in Hamburg and graduated with a master's degree thesis on "Enhancing matrix compression using convoluted tensor products of Chebyshev polynomials". He joined the group of Tobias Knopp for Biomedical Imaging at the University Medical Center Hamburg-Eppendorf (UKE) and the Hamburg University of Technology in 2021 as a PhD student and finished his PhD in 2025 on the topic "On Algorithmical Methods Facilitating Clinical Translation of Magnetic Particle Imaging".

Journal Publications

[191960]
Title: Denoising the system matrix with deep neural networks for better MPI reconstructions.
Written by: A. Tsanda, K. Scheffler, S. Reiss, and T. Knopp
in: <em>International Journal on Magnetic Particle Imaging</em>. Mar (2025).
Volume: <strong>11</strong>. Number: (1 Suppl 1),
on pages:
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DOI: 10.18416/IJMPI.2025.2503047
URL: https://www.journal.iwmpi.org/index.php/iwmpi/article/view/810
ARXIVID:
PMID:

[www]

Note: inproceedings, ml

Abstract: Magnetic Particle Imaging commonly relies on the system matrix (SM) to reconstruct particle distributions, but noise during acquisition limits both its resolution and image quality. Traditionally, noise reduction requires averaging multiple measurements, which increases acquisition time. This paper presents a deep neural network trained on simulated SMs and measured background noise, which effectively generalizes to real-world data. The model recovers higher frequency components of the SM and serves as a general pre-processing step, enhancing image reconstruction quality while reducing the need for extensive averaging, thus accelerating SM acquisition.

Conference Publications

[191960]
Title: Denoising the system matrix with deep neural networks for better MPI reconstructions.
Written by: A. Tsanda, K. Scheffler, S. Reiss, and T. Knopp
in: <em>International Journal on Magnetic Particle Imaging</em>. Mar (2025).
Volume: <strong>11</strong>. Number: (1 Suppl 1),
on pages:
Chapter:
Editor:
Publisher:
Series:
Address:
Edition:
ISBN:
how published:
Organization:
School:
Institution:
Type:
DOI: 10.18416/IJMPI.2025.2503047
URL: https://www.journal.iwmpi.org/index.php/iwmpi/article/view/810
ARXIVID:
PMID:

[www]

Note: inproceedings, ml

Abstract: Magnetic Particle Imaging commonly relies on the system matrix (SM) to reconstruct particle distributions, but noise during acquisition limits both its resolution and image quality. Traditionally, noise reduction requires averaging multiple measurements, which increases acquisition time. This paper presents a deep neural network trained on simulated SMs and measured background noise, which effectively generalizes to real-world data. The model recovers higher frequency components of the SM and serves as a general pre-processing step, enhancing image reconstruction quality while reducing the need for extensive averaging, thus accelerating SM acquisition.