Dr.-Ing. Konrad Scheffler

Portrait of Konrad Scheffler

Universitätsklinikum Hamburg-Eppendorf (UKE)
Sektion für Biomedizinische Bildgebung
Lottestraße 55
2ter Stock, Raum 213
22529 Hamburg
- Postanschrift -

Technische Universität Hamburg (TUHH)
Institut für Biomedizinische Bildgebung
Gebäude E, Raum 4.044
Am Schwarzenberg-Campus 3
21073 Hamburg

Tel.: 040 / 7410 25813
E-Mail: konrad.scheffler(at)tuhh.de
E-Mail: ko.scheffler(at)uke.de

Research Interests

  • Magnetic Particle Imaging
  • Image Reconstruction
  • Image Processing

Curriculum Vitae

Konrad Scheffler studied Technomathematics between 2015 and 2021 in Hamburg and graduated with a master's degree thesis on "Enhancing matrix compression using convoluted tensor products of Chebyshev polynomials". He joined the group of Tobias Knopp for Biomedical Imaging at the University Medical Center Hamburg-Eppendorf (UKE) and the Hamburg University of Technology in 2021 as a PhD student and finished his PhD in 2025 on the topic "On Algorithmical Methods Facilitating Clinical Translation of Magnetic Particle Imaging".

Journal Publications

[191175]
Title: RegularizedLeastSquares.jl: Modality Agnostic Julia Package for Solving Regularized Least Squares Problems.
Written by: N. Hackelberg, M. Grosser, A. Tsanda, F. Mohn, K. Scheffler, M. Möddel, and T. Knopp
in: <em>International Journal on Magnetic Particle Imaging</em>. (2024).
Volume: <strong>10</strong>. Number: (1 Suppl 1),
on pages: 1-4
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DOI: https://doi.org/10.18416/IJMPI.2024.2403028
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Note: inproceedings, reconstruction, opensoftware, generalsoftware

Abstract: Image reconstruction in Magnetic Particle Imaging (MPI) is an ill-posed linear inverse problem. A standard method for solving such a problem is the regularized least squares approach, which uses, a regularization function to reduce the impact of measurement noise in the reconstructed image by leveraging prior knowledge. Various optimization algorithms, including the Kazcmarz method or the Alternating Direction Method of Multipliers (ADMM), and regularization functions, such asl2or Fused Lasso priors have been employed. Therefore, the creation and implementation of cutting-edge image reconstruction techniques necessitate a robust and adaptable optimization framework. In this work, we present the open-source Julia package RegularizedLeastSquares.jl, which provides a large selection of common optimization algorithms and allows flexible inclusion of regularization functions. These features enable the package to achieve state-of-the-art image reconstruction in MPI.

Conference Publications

[191175]
Title: RegularizedLeastSquares.jl: Modality Agnostic Julia Package for Solving Regularized Least Squares Problems.
Written by: N. Hackelberg, M. Grosser, A. Tsanda, F. Mohn, K. Scheffler, M. Möddel, and T. Knopp
in: <em>International Journal on Magnetic Particle Imaging</em>. (2024).
Volume: <strong>10</strong>. Number: (1 Suppl 1),
on pages: 1-4
Chapter:
Editor:
Publisher:
Series:
Address:
Edition:
ISBN:
how published:
Organization:
School:
Institution:
Type:
DOI: https://doi.org/10.18416/IJMPI.2024.2403028
URL:
ARXIVID:
PMID:

Note: inproceedings, reconstruction, opensoftware, generalsoftware

Abstract: Image reconstruction in Magnetic Particle Imaging (MPI) is an ill-posed linear inverse problem. A standard method for solving such a problem is the regularized least squares approach, which uses, a regularization function to reduce the impact of measurement noise in the reconstructed image by leveraging prior knowledge. Various optimization algorithms, including the Kazcmarz method or the Alternating Direction Method of Multipliers (ADMM), and regularization functions, such asl2or Fused Lasso priors have been employed. Therefore, the creation and implementation of cutting-edge image reconstruction techniques necessitate a robust and adaptable optimization framework. In this work, we present the open-source Julia package RegularizedLeastSquares.jl, which provides a large selection of common optimization algorithms and allows flexible inclusion of regularization functions. These features enable the package to achieve state-of-the-art image reconstruction in MPI.