@article{Antonelli2020,
Author = {A. Antonelli, P. Szwargulski, E. S. Scarpa, F. Thieben, C. Grüttner, G. Ambrosi, L. Guidi, P. Ludewig, T. Knopp and M. Magnani},
Title = {Development of long circulating magnetic particle imaging tracers: use of novel magnetic nanoparticles and entrapment into human erythrocytesDevelopment of long circulating magnetic particle imaging tracers: use of novel magnetic nanoparticles and entrapm.},
Journal = {<em>Nanomedicine</em>.},
Year = {(2020).},
Volume = {<strong>15</strong>.},
Number = {(8),},
Pages = {739-753},
Month = {April},
Note = {article},
Publisher = {Future Medicine Ltd:},
Url = {https://doi.org/10.2217/nnm-2019-0449},
Keywords = {intravascular contrast agents, MPS/MPI, NMR, RBCs, SPIO-loaded RBCs, TEM},
Abstract = {Aim: Magnetic particle imaging (MPI) is highly promising for biomedical applications, but optimal tracers for MPI, namely superparamagnetic iron oxide-based contrast agents, are still lacking. Materials & methods: The encapsulation of commercially available nanoparticles, specifically synomag®-D and perimag®, into human red blood cells (RBCs) was performed by a hypotonic dialysis and isotonic resealing procedure. The amounts of superparamagnetic iron oxide incorporated into RBCs were determined by Fe quantification using nuclear magnetic resonance and magnetic particle spectroscopy. Results: Perimag-COOH nanoparticles were identified as the best nanomaterial for encapsulation in RBCs. Perimag-COOH-loaded RBCs proved to be viable cells showing a good magnetic particle spectroscopy performance, while the magnetic signal of synomag-D-COOH-loaded RBCs dropped sharply. Conclusion: Perimag-COOH-loaded RBCs could be a potential tool for MPI diagnostic applications.}
}

@COMMENT{Bibtex file generated on 2026-5-12 with typo3 si_bibtex plugin. Data from https://www.tuhh.de/ibi/people/florian-thieben }