An-Ping Zeng's list of publications
A. Peer Reviewed Papers and Book Chapters
You can find the publications of Prof. Zeng at google scholar or have a look underneath.
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Veröffentlichungen
- Ren J, Wang W, Nie J, Yuan W, Zeng A-P,
Understanding and engineering glycine cleavage system and related metabolic pathways for C1-based biossynthesis
In: A.-P. Zeng, N. Claassen (eds.) One-carbon feedstocks for sustainable Bioproduction, Adv. Biochem. Bioeng./Biotechnol., Springer 2021 (accepted) - Hong Y, Zeng A-P,
Bioprocesses based on one-carbon mixotrophy
In: A.-P. Zeng, N. Claassen (eds.) One-carbon feedstocks for sustainable Bioproduction, Adv. Biochem. Bioeng./Biotechnol., Springer 2021, in print - Zhang C, Sharmal S, Wang W, Zeng A-P,
A novel downstream process for highly pure 1,3-propanediol from
efficient fed-batch fermentation of raw glycerol by
Clostridium pasteurianum
Engineering in Life Science 2021, in print - Nie J, Zhang X, Schroer M, Liu Y, Wang W, Ren J, Svergun D, Zeng A-P,
The enzyme lipoate-protein ligase A of E. coli forms a novel stimuli-
responsive pure protein hydrogel with novel structure and enzymatic activity
bioRxiv 2021 - Nie J, Zhang X, Wang W, Ren J, Zeng A-P,
Tunable protein hydrogels: Present state and emerging development
In: A. Lavrentieva, I. Pepelanova, D. Seliktar (eds.) Tunable hydrogels and their application in biotechnology/medical biotechnology. Adv. Biochem. Bioeng/Biotechnol., Springer 2021, in print - Chen M, Ma C, Chen L, Zeng A-P,
Integrated laboratory evolution and rational engineering of GalP/Glk-
dependent E. coli for higher yield and productivity of L-tryptophan
biosynthesis
Met. Eng. Comm. 2021, 12, e00167 - Meng H, Yuan Q, Ren J, Zeng A-P,
An aldolase-based new pathway for condensation of formaldehyde
and ethanol to synthesize 1,3-propanediol in E. coli
ACS Synth. Biol. 2021 - Xu Y, Li Y, Zhang H, Nie J, Ren, J, Wang W, Zeng A-P,
Stand-alone lipoylated H-protein of the glycine cleavage system enables
glycine cleavage and the synthesis of glycine from one-carbon
compounds in vitro
bioRxiv 2021 - Selder L, Wang W, Groeger C, Sabra W, Zeng A-P,
Bioconversion an downstream processing in the context of biorefinery: principles and process examples
In: M. Aresta et al. (ed.) Biorefineries. De Gruyter Graduate 2021, in print - Arbter P, Sabra W, Utesch T, Hong Y, Zeng A-P,
Metabolomic and kinetic investigations on the electricity-aided
production of butanol by Clostridium pasteurianum strains
Engineering in Life Science 2021 - Wang S, Ma C, Zeng A-P,
Dynamic energy correlation analysis E. coli aspartokinase III
and alteration of allosteric regulation by manipulating energy
transduction pathways
Engineering in Life Science 2021, 21, 314-323 - Zeng A-P,
Fermentation and bioprocess development
Kirk-Othmer Encyclopedia of Chemical Technology. John Wiley & Sons, Inc. Mannheim 2021, in print - Heuer J, Kraus Y, Vucak M, Zeng A-P,
Enhanced sequestration of carbon dioxide into calcium carbonate using pressure and a carbonic anhydrase from alkaliphilic Coleofasciculus chthonoplastes
Engineering in Life Science 2021, in print - Hong Y, Arbter P, Wang W, Rojas L, Zeng A-P,
Introduction of glycine synthase enables assimilation of C1
carbon and strongly impacts the metabolism in Clostridium pasteurianum
Biotechnology and Bioengineering 2020, 1-15 - Möller J, Bhat K, Riecken K, Pörtner R, Jandt U, Zeng A-P,
Lactate metabolism in CHO cells: Investigation of pyruvate
dehydrogenase complex regulation
Engineering in Life Science 2020, 21: 100-114 - Zhang H, Li Y, Nie J, Ren J, Zeng A-P,
Structure-based dynamic analyses of the glycine cleavage
system suggests key residues for control of a key reaction step
Communication Biology 2020, 3 (1), 1-12 - Depta P N, Jandt U, Jacobi C, Dosta M, Zeng A-P, Heinrich S,
Data-driven multiscale modeling of self-assembly and
hierarchical structural formation in biological macromolecular sytems
Chemie Ingenieur Technik 2020, 92, 1249-1249 - Arbter P, Beisch H, Utesch T, Fiedler B, Zeng A-P,
Control of biosynthesis in bioelectrochemical systems
Chemie Ingenieur Technik 2020, 92, 1212-1212 - Zhang X, Nie J, Zheng Y, Ren J, Zeng A-P,
Activation and competition of H protein lipoylation in a
reaction cascade catalyzed by the multifunctional enzyme lipoate-protein ligase A
Biotechnology and Bioengineering 2020, 1-11 - Zeng AP, Bley T, Takors R, Flemming D,
Open Access for the future
Engineering Life Science 2020, 20, 4 - Xu Y, Meng H, Ren J, Zeng A-P,
Formaldehyde formation in the glycine cleavage system and
its use for an aldolase-based biosynthesis of 1,3-propanediol
Journal of Biological Engineering 2020, 14:15, 1-10 - Möller J, Rosenberg M, Riecken K, Pörtner R, Zeng A-P, Jandt U,
Quantification of the dynamics of population heterogeneities in
CHO cultures with stably integrated fluorescent markers
Analytical and Bioanalytical Chemistry 2020, 1-16 - Selder L, Sabra W, Jürgensen N, Lakshmanan A, Zeng A-P,
Co-cultures with integrated in-situ product removal for lactate-based
PA production
Bioprocess Biosyst Eng. 2020, 1-9 - Hong Y, Ren J, Zhang X, Wang W, Zeng A-P,
Quantitative analysis of glycine related metabolic pathways for one-carbon synthetic biology
Current Opinion in Biotechnology 2020, 64, 70-78 - Möller J, Korte K, Pörtner R, Zeng A-P, Jandt U,
Near-Physiological Cell Cycle Synchronization with Countercurrent Centrifugal Elutriation
Animal Cell Biotechnology 2020, 3-16 - Möller J, Bhat K, Riecken K, Pörtner R, Zeng A-P, Jandt U,
Process-induced cell cycle oscillations in CHO cultures: online monitoring and model-based investigation
Biotechnol. Bioeng. 2020, (in print) - Jacobi C, Ilhan S, Steinbrecher T, Khansahib I, Depta N, Dosta M, Heinrich S, Zeng A-P, Jandt U,
Towards Designed Multienzymatic Bioreactions: Changed Assembly
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 2019, 48, 195-195 - Zeng A-P, Takors R, Bley T,
Editorial: Engineering mindset for Life Sciences and Biotechnology
Eng. In Life Sciences 2019, 19, 158-158 - Arbter P, Sinha A, Toresch J, Utesch T, Zeng A-P,
Redox governed electro-fermentation improves lipid production by the oleaginous yeast Rhodosporidium toruloides under aerobic and microaerobic conditions
Bioresource Technol. 2019, 294, 122122 - Zhou L, Ren J, Li Z, Nie J, Wang C, Zeng A-P,
Characterization and engineering of a Clostridium glycine riboswitch and its use to control a novel metabolic pathway for 5-aminolevulinic acid production in Escherichia coli
ACS Synth. Biol. 2019, 8 (10), 2327-2335 - Wang C, Ren J, Zhou L, Li Z, Zeng A-P,
An aldolase-catalyzed new metabolic pathway for the assimilation of formaldehyde and methanol to synthesize 2-keto-4-hydroxybutyrate and 1,3-propanediol in Escherichia coli
ACS Synth. Biol. 2019, 8 (11), 2483-2493 - Zhang X, Li M, Xu Y, Ren J, Zeng A-P,
Quantitative study of H protein lipoylation of the glycine cleavage system and a strategy to increase its activity by co-expression of LplA
J. Biol. Eng. 2019, 32 - Zeng A-P,
New bioproduction systems for chemicals: Needs and new development
Biotechnol. Adv. 2019, 37, 508-518 - ZhangY, Ma C, Dischert W, Soucaille P, Zeng A-P,
Engineering of phosphoserine aminotransferase for L-homoserine conversion to 4-hydroxy-2-ketobutyrate in a glycerol-independent pathway of 1,3-propanediol production from glucose
Biotechnol. J. 2019 - Chen M, Chen L, Zeng A-P,
CRISPR/Cas9-facilitated engineering and growth-coupled in vivo screening of enzyme variants for efficient biosynthesis of L-tryptophan in E. coli
Met. Eng. Commun. 2019, 9 - Depta PN, Jandt U, Dosta M, Zeng A-P, Heinrich S,
Towards multi-scale modeling of proteins and bio-agglomerates: An orientation-sensitive diffusion model for the integration of Molecular Dynamics and the Discrete Element Method
Journal of Chemical Information and Modeling 2019, 59, 386-398 - Utesch T, Groeger C, Sabra W, Baur J, Zeng A-P,
Enhanced electron transfer of different mediators for strictly opposite shifting of metabolism in Clostridium pasteurianum grown on glycerol in a new electrochemical bioreactor
Biotechnol. Bioeng. 2019, 1 - Wurm M, Ilhan S, Jandt U, Zeng A-P,
Direct and Highly Sensitive Measurement of Fluorescent Molecules in Bulk Solutions using Flow Cytometry
Anal. Biochemistry 2019, 570, 32-42 - Enzmann F, Stöckl M, Zeng A-P, Holtmann D,
Same but different - Scaling Up and Numbering Up in Electrobiotechnology and Photobiotechnology
Eng. Life Sci. 2019, 19, 121-132 - Ren J, Zhou L, Wang C, Lin C, Li Z, Zeng A-P,
An unnatural pathway for efficient 5-aminolevulinic acid biosynthesis with glycine from glyoxylate based on retrobiosynthetic design
ACS Synth. Biol. 2018, 7, 2750-2757 - Möller J, Korte K, Pörtner R, Zeng A-P, Jandt U,
Cell-cycle and putative autocrine dependent metabolism in CHO production cell line under near-physiological conditions
Biotechnol. Bioeng. 2018, 115 (12), 2996-3008 - Chen L, Chen M, Ma C, Zeng A-P,
Discovery of feed-forward regulation in L-tryptophan biosynthesis and its use in metabolic engineering of E. Coli for efficient tryptophan bioproduction
Met. Eng. 2018, 47, 434-444 - Zhao H and Zeng A-P,
Preface: Exploring the Synergy between Synthetic Biology and Metabolic Engineering
Adv. Biochem. Bioeng/Biotechnol 2018, 162, V-VI - Utesch T and Zeng A-P,
A Novel "All-In-One" Electrode and Bioreactor Enable Better Study of Electrochemical Effects and Electricity-Aided Bioprocesses
Eng. Life Sci. 2018, 18, 600-610 - Brost R, Sabra W, Hong Y, Utesch T, Zeng A-P,
Improved electrocompetence and metabolic engineering of Clostridium pasteurianum revealed a new regulation pattern of glycerol mono- and cosubstrate fermentation
Eng. Life Sci. 2018 - Wang Z, Liu J, Chen L, Zeng A-P, Solem C, Jensen PR,
Alterations in the transcription factors GntR1 and RamA enhance the growth and central metabolism of Corynebacterium glutamicum
Met. Eng. 2018, 48, 1-12 - Hezayeh S, Zeng A-P, Jandt U,
Full Enzyme Complex Simulation: Interactions in Human Pyruvate Dehydrogenase Complex
J. Chem. Inf. Model. 2018, 58(2), 362-369 - Song L., Zeng A-P,
Orthogonal information encoding in living cells with high error-tolerance, safety and fidelity
ACS. Synth. Biol. 2018, 7 (3), 866–874 - Mora-Villalobos J-A and Zeng, A-P,
Synthetic pathways and pocesses for effective production of 5-hydroxytryptophan and serotonin from glucose in Escherichia coli
J. Biol. Eng. 2018, 12 (1) - Meyne N, Fuge G, Zeng A-P, Jacob AF,
Resonant Microwave Sensors for Picoliter Liquid Characterization and Non-Destructive Detection of Single Biological Cells
IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology 2017 - Jandt U, Hezayeh S, Ilhan S, Zeng A-P,
Full strucural modeling of multi enzymatic nanomachines: flexible domain interacions within pyruvate dehydrogenase complex
FEBS JOURNAL 2017, 284, 79-80 - Sabra W, Bommareddy RR, Maheshwari G, Papanikolaou S, Zeng A-P,
Substrates and oxygen dependant citric acid production by Yarrowia lipolytica: Insights through transcriptome and fluxome analysis
Microbial Cell Factory, 16 - Fuge G, Hong Y, Riecken K, Zeng A-P, Jandt U,
CHO cells engineered for fluorescence read out of cell cycle and growth rate in real time
Biotechnology Progress 2017, 33, 1408-1417 - Qin L, Liu L, Zeng A-P, Wie D,
From low-cost substrates to microbial lipid by oleaginous yeast and microalgae as cell factory
Bioresources Technology 2017, 245, 1507-1519 - Song L., Zeng A-P,
Engineering cells as robots for parallel and highly sensitive screening of biomolecules under in vivo conditions
Sci. Report 2017, 7 (1), 15145 - Mora-Villalobos J-A and Zeng, A-P,
Protein and pathway engineering for the biosynthesis of 5-hydroxytryptophan in Escherichia coli
Eng. Life Sci. 2017, 17, 892-899 - Groeger C,Wang W,Sabra W, Utesch T, Zeng A-P ,
Metabolic and proteomic analysis of producr selectivity and redox regulation in Clostridium pasteurianum grown on glycerol under varied iron availability
Microb. Cell Fact. 2017, 16 (1) - Hezayeh S, Zeng A-P, Jandt U,
Investigation of Core Structure and Stability of Human Pyruvate Dehydrogenase Complex: a Coarse-Grained Approach
ACS Omega 2016, 2 (3), 1134-1145 - Guo J, Hezaveh S, Tatur J, Zeng A-P, Jandt U ,
Reengineering of human pyruvate dehydrogenase complex: from disintegration to highly active agglomerates
Biochemical Journal 2017, 474 (5), 865-875 - Zhao H, Zeng A-P (eds.),
Synthetic Biology - Metabolic Engineering
Adv. Biochem. Eng. /Biotechnol. 2017, 162 - Geng F., Ma C., Zeng A-P,
Reengineering substrate specificity of E. coli glutamate dehydrogenase using a position-based prediction method
Biotechnol. Letter 2017, 39 (4), 599-605 - Fuge G, Zeng A-P, Jandt U,
Weak cell cycle dependency but strong distortive effects of transfection with Lipofectamine 2000 in near-physiologically synchronized cell culture
Eng. Life Sci 2017, 17 (4), 348-356 - Ma C-W, Zhou L, Zeng A-P,
Engineering Biomolecular Switches for Dynamic Metabolic Control
A.-P. Zeng, H. Zhao (eds.) Synthetic Biology and Metabolic Engineering. Adv. Biochem. Eng. /Biotechnol. 2017, 162, 45-67 - Papanikolaou S,Rontou M, Belka A, Athenaki M, Gardeli C, Mallouchos A, Kalantzi O, Koutinas A, Zeng A-P, Aggelis G,
Conversion of biodiesel-derived glycerol into biotechnological products of industrial significance by a relatively broad spectrum of yeasts and fungi.
Eng. Life Sci 2017, 17 (3), 262-281 - da Luz J A, Hans E, Frank D, Zeng, A-P,
Analysis of intracellular metabolites of Corynebacterium glutamicum at high cell density with automated sampling and filtration and assessment of engineered enzymes for effective L-lysine production
Eng. Life Sci 2017, 17, 512-522 - Bommareddy RR, Sabra W, Zeng A-P,
Glucose‐mediated regulation of glycerol uptake in Rhodosporidium toruloides: Insights through transcriptomic analysis on dual substrate fermentation
Eng. Life Sci 2017, 17 (3), 282-291 - Chen L, Zeng A-P,
Rational Design and Metabolic Analysis of Escherichia coli for Effective Production of L-Tryptophan at High Concentration,
Appl. Microbiol. Biotechnol. 2017, 15, 559-568 - Chen Z, Geng F, Zeng A-P,
Erratum: Protein design and engineering of a de novo pathway for microbial production of 1,3-propanediol from glucose
Biotechnology Journal 2016, 11, 1368-1368 - Pörtner R, Jandt U, Zeng A-P,
Cell Culture Technology
JC Liao and C. Wittmann (eds.) Industrial Biotechnology: Products and Processes, Wiley-VCH 2016, 129-158 - Hwang ET, Seo B-K, Gu MB, Zeng A-P,
Successful bi-enzyme stabilization for the biomimetic cascade transformation of carbon dioxide,
Catalysis Science Technology 2016, 6(19), 7267-7272 - Hezaveh S, Zeng A-P, Jandt U ,
Human Pyruvate Dehydrogenase Complex E2 and E3BP Core Subunits: New Models and Insights from Molecular Dynamics Simulations
Journal of Physical Chemistry B 2016, 120, 4399–4409 - Groeger C, Sabra W, Zeng A-P,
Simultaneous production of 1, 3‐propanediol and n‐butanol by Clostridium pasteurianum: In situ gas stripping and cellular metabolism
Eng. Life Sci 2016, 16 (7), 664-674 - Chen Z, Zeng A-P,
Protein engineering approaches to chemical biotechnology
Curr. Opin. Biotechnol. 2016, 42, 198–205 - Sabra W, Wang W, Surandram S, Groeger C, Zeng A-P,
Fermentation of mixed substrates by Clostridium pasteurianum and its physiological, metabolic and proteomic characterizations
Microb Cell Fact 2016, 5 (1), 114- - Sabra W, Groeger C, Zeng A-P,
Microbial cell factories for diol production
Q. Ye and JJ. Zhong et al. (eds.) “Bioreactor Engineering Research and Industrial Applications I: Cell Factories”, Series of “Advances in Biochemical Engineering/Biotechnology” 2016, 155, 165-197 - Zeng A-P, Kaltschmitt M,
Green electricity and bio-wastes via biogas to bulk-chemicals and fuels
Eng. Life Sci. 2016, 16, 211-221 - Sabra W, Roeske I, Sahm K, Antranikian G, Zeng A-P,
Metabolic and microbial characterization of high-temperature biogas reactors treating stillage from an industrial bioethanol process
Eng Life Sci 2015, 15, 743–750 - Zhou L, Bomareddy R R, Zeng A-P,
Engineering lysine-ON riboswitch for metabolic self-control of lysine production in Corynebacterium glutamicum
ACS Synthetic Biology 2015, 4 (12), 1335−1340 - Castillo A E, Fuge G, Jandt U, Zeng A-P,
Growth kinetics and validation of near-physiologically synchronized HEK293s cultures
Eng Life Sci 2015, 15, 509-518 - Bomareddy R R, Sabra W, Maheshwari G, Zeng A-P,
Metabolic network analysis and experimental study of lipid production in Rhodosporidium toruloides grown on single and mixed substrates
Microbil Cell Factory 2015, 14, 36 - Ma CW, Xiu ZL, Zeng A-P,
Exploring signal transduction in heteromultimeric protein based on energy dissipation model
J. Biomol. Struct. & Dyn. 2015, 33, 134-146 - Groeger C, Sabra W, Zeng A-P,
Introduction to Bioconversion and Downstream Processing: Principles and Process Examples
M. Aresta et al. (ed.) Biorefineries. De Gruyter Graduate 2015, 81-104 - Zhou L, Zeng A-P,
Exploring Lysine Riboswitch for Metabolic Flux Control and Improvement of l-Lysine Synthesis in Corynebacterium glutamicum
ACS Synth Biol 2015, 4, 729-734 - Kaeding T, DaLuz J, Kube J, Zeng A-P,
Integrated study of fermentation and downstream processing in a miniplant significantly improved the microbial 1,3-propanediol production from raw glycerol
Bioprocess Biosystems Eng 2015, 38, 575-586 - Jandt U, Platas Barradas O, Pörtner R, Zeng A-P,
Synchronized mammalian cell culture: Part II Population ensemble modeling and analysis for development of reproducible processes
Biotechnol Progress 2015, 31, 175-185 - Platas Barradas O, Jandt U, Bahnemann J, Becker M, Pörtner R, Zeng A-P,
Synchronized mammalian cell culture: Part I A synchronization strategy with further cultivation under physiological conditions
Biotechnol Progress 2015, 31, 165-174 - Chen Z, Rappert S, Zeng A-P,
Rational Design of Allosteric Regulation of Homoserine Dehydrogenase by a Non-Natural Inhibitor L-Lysine
ACS Synth Biol 2015, 4, 126-131 - Chen Z, Geng F, Zeng A-P,
Protein design and engineering of a de novo pathway for microbial production of 1,3-propanediol from glucose
Biotechnology Journal 2015, 10, 284-289 - Oehmke S, Zeng A-P,
Recovery of biologically produced 3-hydroxypropionaldehyde and its dehydrated product acrolein
Eng Life Sci 2015, 15, 133-139 - Meyne N, Fuge G, Hemanth S, Trieu HK, Zeng A-P, Jacob AF,
Broadband dielectric characterization of CHO-K1 cells using miniaturized transmission-line sensor
IEEE Proceedings BioWireleSS 2015, (accepted) - Bley T, Zeng A-P,
Editorial: Biomaterials Made in Bioreactors
Eng Life Sci 2015, 15 (7), 669 - Conrads G, de Soet J J, Song L, Henne K, Sztajer H, Wagner-Döbler I, Zeng A-P,
Comparing the cariogenic species Streptococcus sobrinus and S. mutans on whole genome level
Journal of Oral Microbiology 2014, 6, 6189 - Roeske I, Sabra W, Nacke H, Daniel R, Zeng A-P, Antranikian G, Sahm K,
Microbial community composition and dynamics in high-temperature biogas reactors using industrial bioethanol waste as substrate
Appl Microbiol Biotechnol 2014, 98, 9095-9106 - Rieckenberg F, Ardao I, Rujananon R, Zeng A-P,
Cell-free synthesis of 1,3-propanediol from glycerol with a high yield
Eng Life Sci 2014, 14, 380-386 - Rieckenberg F, Götz K, Hilterhaus L, Liese A, Zeng A-P,
Strategies for reliable and improved large-scale production of Pyrococcus furiosus with integrated purification of hydrogenase I
Bioprocess Biosyst Eng 2014, 37, 2475-2482 - He FQ, Sauermann U, Beer C, Winkelmann S, Yu Z, Sopper S, Zeng A-P, Wirth M,
Identification of molecular sub-1 networks associated with cell survival in a chronically SIVmac infected human CD4+ T-cells
Virology Journal 2014, 11, 152 - Bommareddy RR, Chen Z, Rappert S, Zeng A-P,
A de novo NADPH generation pathway for improving lysine production of Corynebacterium glutamicum by rational design of the coenzyme specificity of glyceraldehyde 3-phosphate dehydrogenase
Metab Eng 2014, 25, 30-37 - Sudhakar P, Reck M, Wang W, He F, Dobler I, Zeng A-P,
Construction and verification of the transcriptional regulatory response network of Streptococcus mutans upon treatment with the biofilm inhibitor carolacton
BMC Genomics 2014, 15, 362 - Gröger C, Sabra W, Zeng A-P,
Co-Produktion von Propandiol und Butanol in Fermentation mit In-Situ-Produkttrennung
Chemie Ingenieur Technik 2014, 10, (in print) - Kubick S, Zeng A-P,
Editorial: New and synthetic bioproduction systems
Eng Life Sci 2014, 14, 338-339 - Sabra W, Groeger C, Sharma PN, Zeng A-P,
Improved n-butanol production by a non-acetone producing Clostridium pasteurianum DSMZ 525 in mixed substrate fermentation
Appl Microbiol Biotechnol 2014, 98, 4267-4276 - Nicolae A, Wahrheit J, Bahnemann J, Zeng A-P, Heinzle E,
Non-stationary 13C metabolic flux analysis of Chinese hamster ovary cells in batch culture using extracellular labeling highlights metabolic reversibility and compartmentation
BMC Syst Biol 2014, 8, 50 - Rajabi N, Bahnemann J, Tzeng T-N, Platas Barradas O, Zeng A-P, Müller J,
Lab-on-a-chip for cell perturbation, lysis, and efficient separation of sub-cellular components in a continuous flow mode
Sensors and Actuators A: Physical 2014, 215, 136-143 - Sabra W, Zeng A-P,
Mixed Microbial Cultures for Industrial Biotechnology: Success, Chance and Challenges
Industrial Biocatalysis (Ed. P. Grunwald) 2014 - Ma C-W, Lüddecke J, Forchhammer K, Zeng A-P,
Population shift of binding pocket size and dynamic correlation analysis shed new light on the anticooperative mechanism of PII protein
Proteins: Structure, Function, and Bioinformatics 2014, 82, 1048-1059 - Jandt U, Platas Barradas O, Pörtner R, Zeng A-P,
Mammalian cell culture synchronization under physiological conditions and population dynamic simulation
Appl Microbiol Biotechnol 2014, 98, 4311-4319 - Bahnemann J, Kayo S, Wahrheit J, Heinzle E, Pörtner R, Zeng A-P,
In search of an effective cell disruption method to isolate intact mitochondria from Chinese hamster ovary cells
Eng Life Sci 2014, 14, 161-169 - Chen Z, Bommareddy RR, Frank D, Rappert S, Zeng A-P,
Deregulation of feedback inhibition of phosphoenolpyruvate carboxylase for improved lysine production in Corynebacterium glutamicum
Appl Environ Microbiol 2014, 80, 1388-1393 - Sabra W, Haddad AM, Zeng A-P,
Comparative physiological study of the wild type and the small colony variant of Pseudomonas aeruginosa 20265 under controlled growth conditions
World J Microbiol Biotechnol 2014, 30, 1027-1036 - da Luz JA, Hans E, Zeng A-P,
Automated fast filtration and on-filter quenching improve the intracellular metabolite analysis of microorganisms
Eng Life Sci 2014, 14, 135-142 - Cumana S, Ardao I, Zeng A-P, Smirnova I,
Glucose-6-phosphate dehydrogenase encapsulated in silica-based hydrogels for operation in a microreactor
Eng Life Sci 2014, 14, 170-179 - He FQ, Wang W, Zheng P, Sudhakar P, Sun J, Zeng A-P,
Essential O2-responsive genes of Pseudomonas aeruginosa and their network revealed by integrating dynamic data from inverted conditions
Integr Biol (Camb) 2014, 6, 215-223 - Dietz D, Zeng A-P,
Efficient production of 1,3-propanediol from fermentation of crude glycerol with mixed cultures in a simple medium
Bioprocess Biosyst Eng 2014, 37, 225-233 - Gu MB, Zeng A-P,
Industrial biotechnology in Asia recent advances in biofuels and biorefinery
Eng Life Sci 2013, 13, 419-420 - Zeng A-P,
Fundamentals and Application of New Bioproduction Systems
Advances in Biochemical Engineering/Biotechnology 2013, 137, 238 - Li J, Wang W, Wang Y, Zeng A-P,
Two-dimensional gel-based proteomic of the caries causative bacterium Streptococcus mutans UA159 and insight into the inhibitory effect of carolacton
Proteomics 2013, 13, 3470-3477 - Bahnemann J, Rajabi N, Fuge G, Barradas O, Müller J, Pörtner R, Zeng A-P,
A New Integrated Lab-on-a-Chip System for Fast Dynamic Study of Mammalian Cells under Physiological Conditions in Bioreactor
Cells 2013, 2, 349-360 - Kayo S, Bahnemann J, Klauser M, Pörtner R, Zeng A-P,
A microfluidic device for immuno-affinity-based separation of mitochondria from cell culture
Lab Chip 2013, 13, 4467-4475 - Platas O, Jandt U, Sandig V, Pörtner R, Zeng A-P,
An integrated synchronization approach for studying cell-cycle dependent processes of mammalian cells under physiological conditions
BMC Proc 2013, 7, 01.03.2014 - Platas O, Sandig V, Pörtner R, Zeng A-P,
Evaluation of process parameters in shake flasks for mammalian cell culture
BMC Proc 2013, 7, 01.03.2014 - Geng J, Bi JX, Zeng A-P, Yuan JQ,
Application of hybrid cybernetic model in simulating myeloma cell culture co-consuming glucose and glutamine with mixed consumption patterns
Process Biochemistry 2013, 48, 955-964 - Jandt U, You C, Zhang YH, Zeng A-P,
Compartmentalization and metabolic channeling for multienzymatic biosynthesis: practical strategies and modeling approaches
Adv Biochem Eng Biotechnol 2013, 137, 41-65 - Ardao I, Hwang ET, Zeng A-P,
In vitro multienzymatic reaction systems for biosynthesis
Adv Biochem Eng Biotechnol 2013, 137, 153-184 - Rappert S, Song L, Sabra W, Wang W, Zeng A-P,
Draft Genome Sequence of Type Strain Clostridium pasteurianum DSM 525 (ATCC 6013), a Promising Producer of Chemicals and Fuels
Genome Announc 2013, 1 - Rajabi N, Bahnemann J, Tzeng T-N, Zeng A-P, Müller J,
Microfluidic Device for the continuous preparation of Eukaryotic cells for metabolic analysis
Proceedings of MEMS, Taiwan 2013 - Rajabi N, Bahnemann J, Wahrheit J, Heinzle E, Zeng A-P, Müller J,
INERTIAI-based Media Exchange and Quenching For Continuous Cell Preparation in a Lab-on-a-Chip
Proceedings of the 3rd European Conference on Microfluidics - Microfluidics 2012 - Heidelberg 2013 - Ma H-W, Zeng A-P,
Reconstruction of Metabolic Network from Genome Information and its Strutural and Functional Analysis
Computational Systems Biology, Second Edition, Elsevier 2013 - Chen Z, Jandt U, Rappert S, Zeng A-P,
Protein-Design für die Entwicklung von industriellen Mikroorganismen
Biospektrum 2013, 19, 99-101 - Song L, Wang W, Conrads G, Rheinberg A, Sztajer H, Reck M, Wagner-Dobler I, Zeng A-P,
Genetic variability of mutans streptococci revealed by wide whole-genome sequencing
BMC Genomics 2013, 14, 430 - Chen Z, Zeng A-P,
Protein design in systems metabolic engineering for industrial strain development
Biotechnol J 2013, 8, 523-533 - Dietz D, Sabra W, Zeng A-P,
Co-cultivation of Lactobacillus zeae and Veillonella criceti for the production of propionic acid
AMB Express 2013, 3, 01.09.2014 - Sabra W, Dietz D, Zeng A-P,
Substrate-limited co-culture for efficient production of propionic acid from flour hydrolysate
Appl Microbiol Biotechnol 2013, 97, 5771-5777 - Rheinberg A, Song L, Wang W, Reck M, Wagner-Dobler I, Zeng A-P, Conrads G,
Key differences in the metabolom between Streptococcus mutans and S. sobrinus as determined by whole-genome comparison of multiple strains
Int. J. od Medical Microbiology 2013, 303, 49-49 - Freund S, Rath A, Platas Barradas O, Skerhutt E, Scholz S, Niklas J, Sandig V, Rose T, Heinzle E, Noll T, et al,
Batch-to-batch variability of two human designer cell lines – AGE1.HN and AGE1.HN.AAT – carried out by different laboratories under defined culture conditions using a mathematical model
Eng Life Sci 2013, 13, 580-592 - Metsoviti M, Zeng A-P, Koutinas AA, Papanikolaou S,
Enhanced 1,3-propanediol production by a newly isolated Citrobacter freundii strain cultivated on biodiesel-derived waste glycerol through sterile and non-sterile bioprocesses
J Biotechnol 2013, 163, 408-418 - Chen L, Chen Z, Zheng P, Sun J, Zeng A-P,
Study and reengineering of the binding sites and allosteric regulation of biosynthetic threonine deaminase by isoleucine and valine in Escherichia coli
Appl Microbiol Biotechnol 2013, 97, 2939-2949 - Geng F, Chen Z, Zheng P, Sun J, Zeng A-P,
Exploring the allosteric mechanism of dihydrodipicolinate synthase by reverse engineering of the allosteric inhibitor binding sites and its application for lysine production
Appl Microbiol Biotechnol 2013, 97, 1963-1971 - Li J, Wang W, Ma Y, Zeng A-P,
Medium optimization and proteome analysis of (R,R)-2,3-butanediol production by Paenibacillus polymyxa ATCC 12321
Appl Microbiol Biotechnol 2013, 97, 585-597 - Ardao I, Zeng A-P,
In silico evaluation of a complex multi-enzymatic system using one-pot and modular approaches: Application to the high-yield production of hydrogen from a synthetic metabolic pathway
Chemical Engineering Science 2013, 87, 183-193 - He F, Chen H, Probst-Kepper M, Geffers R, Eifes S, Del Sol A, Schughart K, Zeng A-P, Balling R,
PLAU inferred from a correlation network is critical for suppressor function of regulatory T cells
Mol Syst Biol 2012, 8, 624 - Schomburg KT, Ardao I, Gotz K, Rieckenberg F, Liese A, Zeng A-P, Rarey M,
Computational biotechnology: prediction of competitive substrate inhibition of enzymes by buffer compounds with protein-ligand docking
J Biotechnol 2012, 161, 391-401 - Metsoviti M, Paraskevaidi K, Koutinas A, Zeng A-P, Papanikolaou S,
Production of 1,3-propanediol, 2,3-butanediol and ethanol by a newly isolated Klebsiella oxytoca strain growing on biodiesel-derived glycerol based media
Process Biochemistry 2012, 47, 1872-1882 - Rajabi N, Hoffmann M, Bahnemann J, Zeng A-P, Schl, uuml, ter M, ller J, ouml, rg,
A Chaotic Advection Enhanced Microfluidic Split-and-Recombine Mixer for the Preparation of Chemical and Biological Probes
JOURNAL OF CHEMICAL ENGINEERING OF JAPAN 2012, 45, 703-707 - Schöpke B, Zeng A-P,
Inference of responsive metabolic pathways from time-series transcriptomic data with consideration of the metabolic network structure
Integr Biol (Camb) 2012, 4, 889-896 - Wurm M, Zeng A-P,
Estimation of protein and metabolite release rates from damaged mammalian cells by using GFP as a marker molecule
Metabolomics 2012, 8, 1081-1089 - Wurm M, Zeng A-P,
Mechanical disruption of mammalian cells in a microfluidic system and its numerical analysis based on computational fluid dynamics
Lab Chip 2012, 12, 1071-1077 - Ma C-W, Xiu Z-L, Zeng A-P,
Discovery of Intramolecular Signal Transduction Network Based on a New Protein Dynamics Model of Energy Dissipation
PLoS One 2012, 7, e31529 - Jandt U, Zeng A-P,
Modeling of intracellular transport and compartmentation
Advances in Biochemical Engineering Biotechnology 2012, 127, 221-249 - Platas Barradas O, Poertner R, Jandt U, Phan LDM, Villanueva ME, Rath A, Reichl U, Schraeder E, Scholz S, Noll T, Sandig V, Zeng A-P,
Evaluation of criteria for bioreactor comparison and operation standardisation for mammalian cell culture
Eng. Life Sciences 2012, 12, 01.11.2018 - Song L, Sudhakar P, Wang W, Conrads G, Brock A, Sun J, Wagner-Dobler I, Zeng A-P,
A genome-wide study of two-component signal transduction systems in eight newly sequenced mutans streptococci strains
BMC Genomics 2012, 13, 128 - Metsoviti M, Paramithiotis S, Drosinos EH, Galiotou-Panayotou M, Nychas G-JE, Zeng A-P, Papanikolaou S,
Screening of bacterial strains capable of converting biodiesel-derived raw glycerol into 1,3-propanediol, 2,3-butanediol and ethanol
Eng Life Sci 2012, 12, 57-68 - Xue X, Li J, Wang W, Sztajer H, Wagner-Dobler I,
The global impact of the delta subunit RpoE of the RNA polymerase on the proteome of Streptococcus mutans
Microbiology 2012, 158, 191-206 - Chatzifragkou A, Aggelis G, Komaitis M, Zeng A-P, Papanikolaou S,
Impact of anaerobiosis strategy and bioreactor geometry on the biochemical response of Clostridium butyricum VPI 1718 during 1,3-propanediol fermentation
Bioresour Technol 2011, 102, 10625-10632 - Ma CW, Xiu ZL, Zeng A-P,
A new concept to reveal protein dynamics based on energy dissipation
PLoS One 2011, 6, e26453 - Sercinoglu O, Platas Barradas O, Sandig V, Zeng A-P, Pörtner R,
DoE of fed-batch processes - model-based design and experimental evaluation
BMC Proc 2011, 5 Suppl 8, P46 - Platas Barradas O, Jandt U, Da Minh Phan L, Villanueva M, Rath A, Reichl U, Schrader E, Scholz S, Noll T, Sandig V, et al,
Criteria for bioreactor comparison and operation standardisation during process development for mammalian cell culture
BMC Proc 2011, 5 Suppl 8, P47 - Schaletzky M, Platas Barradas O, Sievert H, Balabanov S, Zeng A-P, Pörtner R,
Cultivation strategies of a BA/F3 cell line for fundamental cell research
BMC Proc 2011, 5 Suppl 8, P48 - Platas Barradas O, Jandt U, Hass R, Kasper C, Sandig V, Pörtner R, Zeng A-P,
Physical methods for synchronization of a human production cell line
BMC Proc 2011, 5 Suppl 8, P49 - Schrader E, Scholz S, Niklas J, Rath A, Platas Barradas O, Jandt U, Sandig V, Rose T, Pörtner R, Reichl U, et al,
Characterisation of cultivation of the human cell line AGE1.HN.AAT
BMC Proc 2011, 5 Suppl 8, P87 - Stelzer M, Sun J, Kamphans T, Fekete SP, Zeng A-P,
An extended bioreaction database that significantly improves reconstruction and analysis of genome-scale metabolic networks
Integr Biol (Camb) 2011, 3, 1071-1086 - Rujananon R, Prasertsan P, Phongdara A, Panrat T, Sun J, Rappert S, Zeng A-P,
Construction of Recombinant E.coli Expressing Fusion Protein to Produce 1,3-Propanediol
World Academy of Science, Engineering and Technology 2011, 52, 454 - 460 - Zeng A-P,
New biotechnological production systems
Biotechnol J 2011, 6, 907-908 - Chen Z, Rappert S, Sun J, Zeng A-P,
Integrating molecular dynamics and co-evolutionary analysis for reliable target prediction and deregulation of the allosteric inhibition of aspartokinase for amino acid production
J Biotechnol 2011, 154, 248-254 - Chen Z, Meyer W, Rappert S, Sun J, Zeng A-P,
Co-evolutionary analysis enabled rational deregulation of allosteric enzyme inhibition in Corynebacterium glutamicum for lysine production
Appl Environ Microbiol 2011, 77, 4352-4360 - Yu B, Sun J, Bommareddy RR, Song L, Zeng A-P,
Novel (2R,3R)-2,3-butanediol dehydrogenase from potential industrial strain Paenibacillus polymyxa ATCC 12321
Appl Environ Microbiol 2011, 77, 4230-4233 - Jandt U, Shao S, Wirth M, Zeng A-P,
Spatiotemporal modeling and analysis of transient gene delivery
Biotechnol Bioeng 2011, 108, 2205-2217 - Ma H-W, Zeng A-P,
Modularity based Network Decomposition
Encyclopedia of Systems Biology W. Dubitzky, O. Wolkenhauer, K. Cho & H. Yokota (eds.), Springer Science+Business Media, LLC 2012 2011 - Ma H-W, Zeng A-P,
Top-down Network decomposition: methods for identifying modules in complex biological networks
Encyclopedia of Systems Biology W. Dubitzky, O. Wolkenhauer, K. Cho & H. Yokota (eds.), Springer Science+Business Media, LLC 2012 2011 - Zeng A-P, Ma H-W,
Modularity
Encyclopedia of Systems Biology W. Dubitzky, O. Wolkenhauer, K. Cho & H. Yokota (eds.), Springer Science+Business Media, LLC 2012 2011 - Zeng A-P, Sabra W,
Microbial production of diols as platform chemicals: recent progresses
Curr Opin Biotechnol 2011, 22, 749-757 - Chatzifragkou A, Papanikolaou S, Dietz D, Doulgeraki AI, Nychas GJ, Zeng A-P,
Production of 1,3-propanediol by Clostridium butyricum growing on biodiesel-derived crude glycerol through a non-sterilized fermentation process
Appl Microbiol Biotechnol 2011, 91, 101-112 - Sabra W, Dai J-Y Quitmann H, Zeng A-P and Xiu Z-L,
Microbial production of 2, 3-butanediol
Comprehensive Biotechnology. Second edition, Vol. 3: Industrial Biotechnology and Commodity Products. Eds. Moreina and Bai 2011, 87-97 - Kaeding T, Tjahjasari D, Zeng A-P,
1,3-Propanediol and Polytrimethyleneterephthalate
Comprehensive Biotechnology. Vol. 3: Industrial Biotechnology and Commodity Products (eds. Moreina and Bai) 2011, 229-242 - Zeng A-P,
Editorial: From systems biology to biosystems engineering
Eng Life Sci 2010, 10, 380-381 - Sabra W, Dietz D, Tjahjasari D, Zeng A-P,
Biosystems analysis and engineering of microbial consortia for industrial biotechnology
Eng Life Sci 2010, 10, 407-421 - Chen Z, Wilmanns M, Zeng A-P,
Structural synthetic biotechnology: from molecular structure to predictable design for industrial strain development
Trends Biotechnol 2010, 28, 534-542 - Lu X, Sun J, Nimtz M, Wissing J, Zeng A-P, Rinas U,
The intra- and extracellular proteome of Aspergillus niger growing on defined medium with xylose or maltose as carbon substrate
Microb Cell Fact 2010, 9, 23 - Chatzifragkou A, Dietz D, Komaitis M, Zeng A-P, Papanikolaou S,
Effect of biodiesel-derived waste glycerol impurities on biomass and 1,3-propanediol production of Clostridium butyricum VPI 1718
Biotechnol Bioeng 2010, 107, 76-84 - Wurm M, Schöpke B, Lutz D, Muller J, Zeng A-P,
Microtechnology meets systems biology: the small molecules of metabolome as next big targets
J Biotechnol 2010, 149, 33-51 - Grote R, Schöpke B, Zeng A-P, Antranikian G,
Biotransformationsreaktionen in Mikrosystemtechnik - Visionen für die Industrielle Biotechnik
In: "Nach uns, ohne Öl: Auf dem Weg zu nachhaltiger Produktion" M Angrick (Ed),Metropolis-Verlag, Marburg 2010, 129-141 - Aydoğan Ö, Bayraktar E, Mehmetoğlu Ü, Kaeding T, Zeng A-P,
Selection and optimization of an aqueous two-phase system for the recovery of 1,3-propandiol from fermentation broth
Eng Life Sci 2010, 10, 121-129 - Bizukojc M, Dietz D, Sun J, Zeng A-P,
Metabolic modelling of syntrophic-like growth of a 1,3-propanediol producer, Clostridium butyricum, and a methanogenic archeon, Methanosarcina mazei, under anaerobic conditions
Bioprocess Biosyst Eng 2010, 33, 507-523 - He F, Balling R, Zeng A-P,
Reverse engineering and verification of gene networks: principles, assumptions, and limitations of present methods and future perspectives
J Biotechnol 2009, 144, 190-203 - Zeng A-P, Sun J,
Continouous culture
Manual of Industrial Microbiology and Biotechnology. 3nd. edition, R.H. Baltz, J.E. Davies and A. L. Demain (Eds.), American Society for Microbiology, Washington, D.C. 2009, 685-699 - Flipphi M, Sun J, Robellet X, Karaffa L, Fekete E, Zeng A-P, Kubiecek CP,
Biodiversity and evolution of primary carbon metabolism in Aspergillus nidulans and other Aspergillus spp
Fungal Genet Biol 2009, 46 Suppl 1, S19-S44 - Wortman JR, Gilsenan JM, Joardar V, Deegan J, Clutterbuck J, Andersen MR, Archer D, Bencina M, Braus G, Coutinho P, et al,
The 2008 update of the Aspergillus nidulans genome annotation: a community effort
Fungal Genet Biol 2009, 46 Suppl 1, S2-13 - Hilterhaus L, Minow B, Muller J, Berheide M, Quitmann H, Katzer M, Thum O, Antranikian G, Zeng A-P, Liese A,
Practical application of different enzymes immobilized on sepabeads
Bioprocess Biosyst Eng 2008, 31, 163-171 - Sun J, Zeng A-P,
Systems Biotechnology
2008 Report on the Development of Industrial Biotechnology Ed The Bureau of Life Science & Biotechnology, Chinese Academy of Sciences, Science Press, Beijing 2008 - Liu YH, Bi JX, Zeng A-P, Yuan JQ,
A simple kinetic model for myeloma cell culture with consideration of lysine limitation
Bioprocess Biosyst Eng 2008, 31, 569-577 - Xiu ZL, Zeng A-P,
Present state and perspective of downstream processing of biologically produced 1,3-propanediol and 2,3-butanediol
Appl Microbiol Biotechnol 2008, 78, 917-926 - da Silva MR, Hongwu M, An-Ping Z,
Centrality, Network Capacity, and Modularity as Parameters to Analyze the Core-Periphery Structure in Metabolic Networks
Proceedings of the IEEE 2008, 96, 1411-1420 - Liu Y-H, Bi J-X, Zeng A-P, Yuan J-Q,
A cybernetic model to describe the dynamics of myeloma cell cultivations
Applied Mathematics and Computation 2008, 205, 84-97 - Zhang Q, Teng H, Sun Y, Xiu Z, Zeng A,
Metabolic flux and robustness analysis of glycerol metabolism in Klebsiella pneumoniae
Bioprocess Biosyst Eng 2008, 31, 127-135 - Sun Y-Q, Qi W-T, Hu T, Xiu Z-L, Zeng A-P,
Mathematical Modeling of Glycerol Fermentation by Klebsiella pneumoniae: Concerning Both Enzyme-Catalytic Reductive Pathway and Transport of Glycerol and 1,3-Propanediol Across Cell Membrane
Biochem. Eng. J. 2008, 38, 22-32 - Ulmer C, Zeng A-P,
Microbial production of 3-hydroxypropionaldehyde from glycerol bioconversion
Chemical and Biochemical Engineering Quarterly 2007, 21, 321-326 - Zheng P, Sun J, Geffers R, Zeng A-P,
Functional characterization of the gene PA2384 in large-scale gene regulation in response to iron starvation in Pseudomonas aeruginosa
J Biotechnol 2007, 132, 342-352 - Liu YH, Bi JX, Zeng A-P, Yuan JQ,
A population balance model describing the cell cycle dynamics of myeloma cell cultivation
Biotechnol Prog 2007, 23, 1198-1209 - Pel HJ, de Winde JH, Archer DB, Dyer PS, Hofmann G, Schaap PJ, Turner G, de Vries RP, Albang R, Albermann K, et al,
Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88
Nat Biotechnol 2007, 25, 221-231 - He F, Buer J, Zeng A-P, Balling R,
Dynamic cumulative activity of transcription factors as a mechanism of quantitative gene regulation
Genome Biol 2007, 8, R181 - Sun J, Lu X, Rinas U, Zeng A-P,
Metabolic peculiarities of Aspergillus niger disclosed by comparative metabolic genomics
Genome Biol 2007, 8, R182 - Silva MRd, Ma H, Sun J, He F, Zeng A-P,
Metabolic network
In B H Junker, F Schreiber (eds) Biological Network Analysis, Wiley 2007, 233-253 - Ma B, He F, Jablonska J, Winkelbach S, Lindenmaier W, Zeng A-P, Dittmar KE,
Six-color segmentation of multicolor images in the infection studies of Listeria monocytogenes
Microsc Res Tech 2007, 70, 171-178 - Zhou F, Bi J, Zeng A-P, Yuan J,
A macrokinetic model for myeloma cell culture based on stoichiometric balance
Biotechnol Appl Biochem 2007, 46, 85-95 - Li Y, Bi J, Zhou W, Huang Y, Sun L, Zeng A-P, Ma G, Su Z,
Characterization of the large size aggregation of Hepatitis B virus surface antigen (HBsAg) formed in ultrafiltration process
Process Biochemistry 2007, 42, 315-319 - Zhang Q, Xiu Z-L,, Zeng A-P,
Optimization of microbial production of 1,3-propanediol by Klebsiella pneumoniae under anaerobic and microaerobic conditions by metabolic flux analysis
Chem. Ind. Eng. 2006, 57, 1403-1409 - Wang W, Sun J, Hollmann R, Zeng A-P, Deckwer WD,
Proteomic characterization of transient expression and secretion of a stress-related metalloprotease in high cell density culture of Bacillus megaterium
J Biotechnol 2006, 126, 313-324 - Zheng P, Sun J, van den Heuvel J, Zeng A-P,
Discovery and investigation of a new, second triose phosphate isomerase in Klebsiella pneumoniae
J Biotechnol 2006, 125, 462-473 - Zeng A-P,
Editorial
Process Biochemistry 2006, 41, 2101-2102 - Zheng P, Wereath K, Sun J, van den Heuvel J, Zeng A-P,
Overexpression of genes of the dha regulon and its effects on cell growth, glycerol fermentation to 1,3-propanediol and plasmid stability in Klebsiella pneumoniae
Process Biochemistry 2006, 41, 2160-2169 - Zhou F, Bi J-X, Zeng A-P, Yuan J-Q,
A macrokinetic and regulator model for myeloma cell culture based on metabolic balance of pathways
Process Biochemistry 2006, 41, 2207-2217 - Sun J, Wang W, Hundertmark C, Zeng A-P, Jahn D, Deckwer WD,
A protein database constructed from low-coverage genomic sequence of Bacillus megaterium and its use for accelerated proteomic analysis
J Biotechnol 2006, 124, 486-495 - Deckwer WD, Jahn D, Hempel D, Zeng A-P,
Systems Biology Approaches to Bioprocess Development
Eng Life Sci 2006, 6, 455-469 - Deckwer WD, Hempel DC, Zeng A-P, Jahn D,
Systembiotechnologische Ansätze zur Prozessentwicklung
Chemie Ingenieur Technik 2006, 78, 193-208 - He F, Zeng A-P,
In search of functional association from time-series microarray data based on the change trend and level of gene expression
BMC Bioinformatics 2006, 7, 69 - Wee YJ, Yun JS, Lee YY, Zeng A-P, Ryu HW,
Recovery of lactic acid by repeated batch electrodialysis and lactic acid production using electrodialysis wastewater
J Biosci Bioeng 2005, 99, 104-108 - Buer J, Westendorf AM, Zeng A-P, He F, Hansen W, Probst-Kepper M,
Mechanisms of Central and Peripheral T-Cell Tolerance: An Update
Transfusion Medicine and Hemotherapy 2005, 32, 384-399 - Zhang F, Bi JX, Zeng A-P, Yuan JQ,
A simple kinetic model for myeloma cell growth with lysin as a limiting substrate
J of Shanghai Jiaotong University 2005, 139, 182-186 - Zeng A-P, Bi J,
Cell Culture Kinetics and Modeling
In: SS Ozturk and W-S Hu (eds) Cell Culture Technology for Pharmaceutical and Cellular Therapies Taylor & Francis Group, Atlanta 2005, 299-347 - Kumar B, Ma H, Zeng A-P,
An integrated cellular network of Escherichia coli and its structural analysis
Proceedings of Foundation of Systems Biology in Engineering University of California , Santa Babara , USA , August 7-10 2005, 107-110 - Sun J, Gunzer F, Westendorf AM, Buer J, Scharfe M, Jarek M, Gossling F, Blocker H, Zeng A-P,
Genomic peculiarity of coding sequences and metabolic potential of probiotic Escherichia coli strain Nissle 1917 inferred from raw genome data
J Biotechnol 2005, 117, 147-161 - Zeng A-P, Sun J, Wang W, Ma H, Deckwer W-D,
Application of genomic and proteomic data for bioprocess analysis and optimisation
In ST Yang (ed) Bioprocessing for value-added products from renewable resources Elservier Inc, USA 2005, 25-48 - Kim EJ, Wang W, Deckwer WD, Zeng A-P,
Expression of the quorum-sensing regulatory protein LasR is strongly affected by iron and oxygen concentrations in cultures of Pseudomonas aeruginosa irrespective of cell density
Microbiology 2005, 151, 1127-1138 - Ditges U, Hartmann M, Coldewey S, Ma H, Zeng A-P, Gunzer F,
Acid resistance in enterohemorrhagic E-coli: Is there a link to the serotype ?
International Journal of Medical Microbiology 2004, 294, 161-161 - Feng H, Hongwu M, Xueming Z, Yingjin Y, Anping Z,
- Ma HW, Buer J, Zeng A-P,
Hierarchical structure and modules in the Escherichia coli transcriptional regulatory network revealed by a new top-down approach
BMC Bioinformatics 2004, 5, 199 - Ma HW, Kumar B, Ditges U, Gunzer F, Buer J, Zeng A-P,
An extended transcriptional regulatory network of Escherichia coli and analysis of its hierarchical structure and network motifs
Nucleic Acids Res 2004, 32, 6643-6649 - Ma HW, Zeng A-P,
Phylogenetic comparison of metabolic capacities of organisms at genome level
Mol Phylogenet Evol 2004, 31, 204-213 - Ma HW, Zhao XM, Yuan YJ, Zeng A-P,
Decomposition of metabolic network into functional modules based on the global connectivity structure of reaction graph
Bioinformatics 2004, 20, 1870-1876 - Sun J, Daniel R, Wagner-Dobler I, Zeng A-P,
Is autoinducer-2 a universal signal for interspecies communication: a comparative genomic and phylogenetic analysis of the synthesis and signal transduction pathways
BMC Evol Biol 2004, 4, 36 - Sun J, Zeng A-P,
IdentiCS--identification of coding sequence and in silico reconstruction of the metabolic network directly from unannotated low-coverage bacterial genome sequence
BMC Bioinformatics 2004, 5, 112 - Xiu Z-L, Song B-H, Wang Z-T, Sun L-H, Feng E-M, Zeng A-P,
Optimization of dissimilation of glycerol to 1,3-propanediol by Klebsiella pneumoniae in one- and two-stage anaerobic cultures
Biochemical Engineering Journal 2004, 19, 189-197 - Zeng A-P, Kim E-J,
Iron availability, oxygen limitation, Pseudomonas aeruginosa and cystic fibrosis
Microbiology 2004, 150, 516-518 - Bi JX, Buhr P, Zeng A-P, Wirth M,
Human c-fos promoter mediates high-level, inducible expression in various mammalian cell lines
Biotechnol Bioeng 2003, 81, 848-854 - Kim EJ, Sabra W, Zeng A-P,
Iron deficiency leads to inhibition of oxygen transfer and enhanced formation of virulence factors in cultures of Pseudomonas aeruginosa PAO1
Microbiology 2003, 149, 2627-2634 - Ma H, Zeng A-P,
Reconstruction of metabolic networks from genome data and analysis of their global structure for various organisms
Bioinformatics 2003, 19, 270-277 - Ma HW, Zeng A-P,
The connectivity structure, giant strong component and centrality of metabolic networks
Bioinformatics 2003, 19, 1423-1430 - Qiao JJ, Yuan YJ, Zhao H, Wu JC, Zeng A-P,
Apoptotic cell death in suspension cultures of Taxus cuspidata co-treated with salicylic acid and hydrogen peroxide
Biotechnol Lett 2003, 25, 387-390 - Qiao JJ, Zhao H, Ge ZQ, Yuan YJ, Zeng A-P,
[2-dimensional gel electrophoresis on protein patterns from suspension cultures of Taxus cuspidate induced by SA]
Sheng Wu Gong Cheng Xue Bao 2003, 19, 92-96 - Sabra W, Lunsdorf H, Zeng A-P,
Alterations in the formation of lipopolysaccharide and membrane vesicles on the surface of Pseudomonas aeruginosa PAO1 under oxygen stress conditions
Microbiology 2003, 149, 2789-2795 - Sun J, van den Heuvel J, Soucaille P, Qu Y, Zeng A-P,
Comparative genomic analysis of dha regulon and related genes for anaerobic glycerol metabolism in bacteria
Biotechnol Prog 2003, 19, 263-272 - Wang W, Sun J, Hartlep M, Deckwer WD, Zeng A-P,
Combined use of proteomic analysis and enzyme activity assays for metabolic pathway analysis of glycerol fermentation by Klebsiella pneumoniae
Biotechnol Bioeng 2003, 83, 525-536 - Wang W, Sun J, Nimtz M, Deckwer WD, Zeng A-P,
Protein identification from two-dimensional gel electrophoresis analysis of Klebsiella pneumoniae by combined use of mass spectrometry data and raw genome sequences
Proteome Sci 2003, 1, 6 - Bi JX, Wirth M, Beer C, Kim EJ, Gu MB, Zeng A-P,
Dynamic characterization of recombinant Chinese hamster ovary cells containing an inducible c-fos promoter GFP expression system as a biomarker
J Biotechnol 2002, 93, 231-242 - Hartlep M, Hussmann W, Prayitno N, Meynial-Salles I, Zeng A-P,
Study of two-stage processes for the microbial production of 1,3-propanediol from glucose
Appl Microbiol Biotechnol 2002, 60, 60-66 - Ma Z-Y, Yuan Y-J, Wu J-C, Zeng A-P,
Apoptotic cell death in suspension cultures of Taxus chinensis var. mairei
Biotechnol Lett 2002, 24, 573-577 - Modak J, Deckwer WD, Zeng A-P,
Metabolic control analysis of eucaryotic pyruvate dehydrogenase multienzyme complex
Biotechnol Prog 2002, 18, 1157-1169 - Sabra W, Kim EJ, Zeng A-P,
Physiological responses of Pseudomonas aeruginosa PAO1 to oxidative stress in controlled microaerobic and aerobic cultures
Microbiology 2002, 148, 3195-3202 - Xiu ZL, Chang ZY, Zeng A-P,
Nonlinear dynamics of regulation of bacterial trp operon: model analysis of integrated effects of repression, feedback inhibition, and attenuation
Biotechnol Prog 2002, 18, 686-693 - Xiu Z-L, Song B-H, Sun L-H, Zeng A-P,
Theoretical analysis of effects of metabolic overflow and time delay on the performance and dynamic behavior of a two-stage fermentation process
Biochemical Engineering Journal 2002, 11, 101-109 - Yuan Y-J, Li C, Hu Z-D, Wu J-C, Zeng A-P,
Fungal elicitor-induced cell apoptosis in suspension cultures of Taxus chinensis var. mairei for taxol production
Process Biochemistry 2002, 38, 193-198 - Yuan Y-J, Ma Z-Y, Wu J-C, Zeng A-P,
Taxol-induced apoptotic cell death in suspension cultures of Taxus cuspidata
Biotechnol Lett 2002, 24, 615-618 - Zeng A-P, Biebl H,
Bulk chemicals from biotechnology: the case of 1,3-propanediol production and the new trends
Adv Biochem Eng Biotechnol 2002, 74, 239-259 - Zeng A-P, Modak J, Deckwer WD,
Nonlinear dynamics of eucaryotic pyruvate dehydrogenase multienzyme complex: decarboxylation rate, oscillations, and multiplicity
Biotechnol Prog 2002, 18, 1265-1276 - Sabra W, Zeng A-P, Deckwer WD,
Bacterial alginate: physiology, product quality and process aspects
Appl Microbiol Biotechnol 2001, 56, 315-325 - Yuan Y-J, Z.Y. M, Z.Q G, Z.Q. M, Zeng A-P,
Apoptosis and taxol production in suspension cultures of Taxus spp. cells
J Chem Ind Eng 2001, 51, 4 - Sabra W, Zeng A-P, Lunsdorf H, Deckwer WD,
Effect of oxygen on formation and structure of Azotobacter vinelandii alginate and its role in protecting nitrogenase
Appl Environ Microbiol 2000, 66, 4037-4044 - Xiu Z-L, Zeng A-P, An LJ, Deckwer W-D,
Transient responses and mathematical modeling of Klebsiella pneumoniae to dilution rate and glycerol concentration step changes in continuous culture
J Chemical Engineering of Chinese Universities 2000, 14, 53-58 - Zeng A-P, Linz M,
Programmed cell death (apoptosis) in animal cell culture: physiological and kinetic aspects
In: JJ Zhong (ed): Advances in Applied Biotechnology ECUST Press, Shanghai 2000, 64-77 - Biebl H, Menzel K, Zeng A-P, Deckwer WD,
Microbial production of 1,3-propanediol
Appl Microbiol Biotechnol 1999, 52, 289-297 - Brandt S, Zeng A-P, Deckwer WD,
Adsorption capacity as a key parameter for enzyme induction and pentachlorophenol degradation in Mycobacterium chlorophenolicum PCP-1
Biotechnol Bioeng 1999, 65, 93-99 - Sabra W, Zeng A-P, Sabry S, Omar S, Deckwer WD,
Effect of phosphate and oxygen concentrations on alginate production and stoichiometry of metabolism of Azotobacter vinelandii under microaerobic conditions
Appl Microbiol Biotechnol 1999, 52, 773-780 - Xiu ZL, Deckwer WD, Zeng A-P,
Estimation of rates of oxygen uptake and carbon dioxide evolution of animal cell culture using material and energy balances
Cytotechnology 1999, 29, 159-166 - Zeng A-P,
Continuous culture
In: Manual of Industrial Microbiology and Biotechnology 2nd edition, A L Demain and N A Solomon (Eds), American Society for Microbiology, Washington, DC 1999, 151-164 - Zeng A-P, Deckwer WD,
Model simulation and analysis of perfusion culture of mammalian cells at high cell density
Biotechnol Prog 1999, 15, 373-382 - Zhilong X, Anping Z,
A Study Progress in Oscillatory and Chaotic Behavior in Microbial Continuous Cultures
Progress in Biotechnology 1999, 58-63 - Ahrens K, Menzel K, Zeng A, Deckwer W,
Kinetic, dynamic, and pathway studies of glycerol metabolism by Klebsiella pneumoniae in anaerobic continuous culture: III. Enzymes and fluxes of glycerol dissimilation and 1,3-propanediol formation
Biotechnol Bioeng 1998, 59, 544-552 - Biebl H, Zeng A-P, Menzel K, Deckwer WD,
Fermentation of glycerol to 1,3-propanediol and 2,3-butanediol by Klebsiella pneumoniae
Appl Microbiol Biotechnol 1998, 50, 24-29 - Menzel K, Ahrens K, Zeng A, Deckwer W,
Kinetic, dynamic, and pathway studies of glycerol metabolism by Klebsiella pneumoniae in anaerobic continuous culture: IV. Enzymes and fluxes of pyruvate metabolism
Biotechnol Bioeng 1998, 60, 617-626 - Wittmann C, Zeng A-P, Deckwer WD,
Physiological characterization and cultivation strategies of the pentachlorophenol-degrading bacteria Sphingomonas chlorophenolica RA2 and Mycobacterium chlorophenolicum PCP-1
Journal of Industrial Microbiology and Biotechnology 1998, 21, 315-321 - Xiu ZL, Zeng A-P, Deckwer WD,
Multiplicity and stability analysis of microorganisms in continuous culture: effects of metabolic overflow and growth inhibition
Biotechnol Bioeng 1998, 57, 251-261 - Zeng A-P, Deckwer WD,
88. Neue Ansätze zur Modellierung, Regelung und Überwachung tierischer Zellkulturen
Chemie Ingenieur Technik 1998, 70, 1127-1128 - Zeng A-P, Deckwer WD, Hu WS,
Determinants and rate laws of growth and death of hybridoma cells in continuous culture
Biotechnol Bioeng 1998, 57, 642-654 - Zeng A-P, Hu WS, Deckwer WD,
Variation of stoichiometric ratios and their correlation for monitoring and control of animal cell cultures
Biotechnol Prog 1998, 14, 434-441 - Brandt S, Zeng A-P, Deckwer WD,
3.0.CO;2-8>Adsorption and desorption of pentachlorophenol on cells of Mycobacterium chlorophenolicum PCP-1
Biotechnol Bioeng 1997, 55, 480-489 - Linz M, Zeng A-P, Wagner R, Deckwer WD,
Stoichiometry, kinetics, and regulation of glucose and amino acid metabolism of a recombinant BHK cell line in batch and continuous cultures
Biotechnol Prog 1997, 13, 453-463 - Menzel K, Zeng A-P, Deckwer WD,
Enzymatic evidence for an involvement of pyruvate dehydrogenase in the anaerobic glycerol metabolism of Klebsiella pneumoniae
J Biotechnol 1997, 56, 135-142 - Menzel K, Zeng A-P, Deckwer WD,
High concentration and productivity of 1,3-propanediol from continuous fermentation of glycerol by Klebsiella pneumoniae
Enzyme and Microbial Technology 1997, 20, 82-86 - Xiu Z-L, Zeng A-P, Deckwer W-D,
Model analysis concerning the effects of growth rate and intracellular tryptophan level on the stability and dynamics of tryptophan biosynthesis in bacteria
J Biotechnol 1997, 58, 125-140 - Menzel K, Zeng A-P, Biebl H, Deckwer WD,
3.0.CO;2-J>Kinetic, dynamic, and pathway studies of glycerol metabolism by Klebsiella pneumoniae in anaerobic continuous culture: I. The phenomena and characterization of oscillation and hysteresis
Biotechnol Bioeng 1996, 52, 549-560 - Zeng A-P,
3.0.CO;2-H>Mathematical modeling and analysis of monoclonal antibody production by hybridoma cells
Biotechnol Bioeng 1996, 50, 238-247 - Zeng A-P,
Quantitative assessment of effect of cell density on metabolism and monoclonal antibody production of hybridoma cells
J Biotechnol 1996, 45, 243-251 - Zeng A-P,
Pathway and kinetic analysis of 1,3-propanediol production from glycerol fermentation by Clostridium butyricum
Bioprocess Engineering 1996, 14, 169-175 - Zeng A-P, Menzel K, Deckwer WD,
3.0.CO;2-H>Kinetic, dynamic, and pathway studies of glycerol metabolism by Klebsiella pneumoniae in anaerobic continuous culture: II. Analysis of metabolic rates and pathways under oscillation and steady-state conditions
Biotechnol Bioeng 1996, 52, 561-571 - Zeng A-P, Deckwer W-D,
Bioreaction techniques under low oxygen tension and oxygen limitation: from molecular level to pilot plant reactor
Chemical Engineering Science 1996, 51, 2305-2314 - Solomon BO, Zeng A-P, Biebl H, Schlieker H, Posten C, Deckwer WD,
Comparison of the energetic efficiencies of hydrogen and oxychemicals formation in Klebsiella pneumoniae and Clostridium butyricum during anaerobic growth on glycerol
J Biotechnol 1995, 39, 107-117 - Wittmann C, Zeng A-P, Deckwer WD,
Growth inhibition by ammonia and use of a pH-controlled feeding strategy for the effective cultivation of Mycobacterium chlorophenolicum
Appl Microbiol Biotechnol 1995, 44, 519-525 - Zeng A-P,
A new balance equation of reducing equivalents for data consistency check and bioprocess calculation
J Biotechnol 1995, 43, 111-124 - Zeng A-P,
A kinetic model for product formation of microbial and mammalian cells
Biotechnol Bioeng 1995, 46, 314-324 - Zeng A-P,
Effect of CO2 absorption on the measurement of CO2 evolution rate in aerobic and anaerobic continuous cultures
Appl Microbiol Biotechnol 1995, 42, 688-691 - Zeng A-P, Deckwer WD,
Mathematical modeling and analysis of glucose and glutamine utilization and regulation in cultures of continuous mammalian cells
Biotechnol Bioeng 1995, 47, 334-346 - Zeng A-P, Deckwer WD,
A kinetic model for substrate and energy consumption of microbial growth under substrate-sufficient conditions
Biotechnol Prog 1995, 11, 71-79 - Zeng A-P, Menzel K, Biebl H, Deckwer W-D,
Analysis of oscillation and hysteresis in continuous fermentation of glycerol by K. pneumoniae
In RD Schmid (ed) Biochemical Engineering 1995, 3, 174-177 - A.-P. Zeng PG, W.-D. Deckwer,
Bioenergetic concepts applied to the modelling of a microaerobic process
In TK Ghose (ed) Process Computations in Biotechnology 1994, II, 376-394 - Byun TG, Zeng A-P, Deckwer WD,
Reactor comparison and scale-up for the microaerobic production of 2,3-butanediol by Enterobacter aerogenes at constant oxygen transfer rate
Bioprocess Engineering 1994, 11, 167-175 - Solomon BO, Zeng A-P, Biebl H, Ejiofor AO, Posten C, Deckwer WD,
Effects of substrate limitation on product distribution and H2/CO2 ratio inKlebsiella pneumoniae during anaerobic fermentation of glycerol
Appl Microbiol Biotechnol 1994, 42, 222-226 - Wittmann C, Zeng A-P, Deckwer W-D,
Minimal nutrient requirement for growth ofMycobacterium chlorophenolicum
Biotechnol Lett 1994, 16, 1103-1106 - Zeng A-P, Byun TG, Posten C, Deckwer WD,
Use of respiratory quotient as a control parameter for optimum oxygen supply and scale-up of 2,3-butanediol production under microaerobic conditions
Biotechnol Bioeng 1994, 44, 1107-1114 - Zeng A-P, Ross A, Biebl H, Tag C, Gunzel B, Deckwer WD,
Multiple product inhibition and growth modeling of clostridium butyricum and klebsiella pneumoniae in glycerol fermentation
Biotechnol Bioeng 1994, 44, 902-911 - Zeng A-P, Deckwer W-D,
Pathway analysis of oxygen utilization and tricarboxylic acid cycle activity in Saccharomyces cerevisiae growing on glucose
J Biotechnol 1994, 37, 67-77 - Zeng A-P, Biebl H, Schlieker H, Deckwer WD,
Pathway analysis of glycerol fermentation by Klebsiella pneumoniae: Regulation of reducing equivalent balance and product formation
Enzyme and Microbial Technology 1993, 15, 770-779 - A.-P. Zeng T-GB, W.-D. Deckwer,
Die Ausnutzung des Tricarbonsäurezyklus: Eine wichtige Kenngröße zur Führung mikroaerober Prozesse
Chem-Ing-Tech 1992, 64, 731-734 - Zeng A-P, Deckwer WD,
Utilization of the tricarboxylic acid cycle, a reactor design criterion for the microaerobic production of 2,3-butanediol
Biotechnol Bioeng 1992, 40, 1078-1084 - Zeng A-P, Biebl H, Deckwer WD,
Production of 2,3-butanediol in a membrane bioreactor with cell recycle
Appl Microbiol Biotechnol 1991, 34, 463-468 - Zeng A-P, Byun TG, Deckwer WD,
On-line estimation of viable biomass of a microaerobic culture using exit gas analysis
Biotechnology Techniques 1991, 5, 247-250 - Zeng A-P, Deckwer W-D,
A model for multiproduct-inhibited growth of Enterobacter aerogenes in 2,3-butanediol fermentation
Appl Microbiol Biotechnol 1991, 35, 01.03.2014 - Zeng A-P, Ross A, Deckwer WD,
A method to estimate the efficiency of oxidative phosphorylation and biomass yield from atp of a facultative anaerobe in continuous culture
Biotechnol Bioeng 1990, 36, 965-969 - Zeng A-P, Biebl H, Deckwer W-D,
2,3-Butanediol production by Enterobacter aerogenes in continuous culture: role of oxygen supply
Appl Microbiol Biotechnol 1990, 33, 264-268 - Zeng A-P, Biebl H, Deckwer W-D,
Effect of pH and acetic acid on growth and 2,3-butanediol production of Enterobacter aerogenes in continuous culture
Appl Microbiol Biotechnol 1990, 33, 485-489
PROGRESS AND PERSPECTIVE IN APPLICATION OF BIOINFORMATICS TO ANALYSIS OF METABOLIC NETWORKS
CIESC Journal 2004, 55, 1593-1601
B. Books/Monographs/Theses
5. A.-P. Zeng (ed.) (2013) Fundamentals and application of new bioproduction systems. Adv Biochem Engin/Biotechnol, Springer-Verlag, Berlin (in print).
4. K. Schügerl and A.-P. Zeng (Eds.) (2002) Tools and Applications of Biochemical Engineering Science. Volume 74. Advances in Biochemical Engineering/Biotechnology. Springer-Verlag, Heidelberg.
3. Habilitationschrift (2000) Quantitative Zellphysiologie, Metabolic Engineering und Modellierung der Glycerinfermentation zu 1,3-Propandiol. Technische Universität Braunschweig.
2. A.-P. Zeng (1999) Sections Upstream Processing, Products and Processes (over 50 pages) in the Encyclopaedia "Römpp Lexikon Biotechnologie/Gentechnik", 2nd Edition, (Eds.) W.-D. Deckwer, A. Pühler, R.D Schmid, Thieme Verlag, Stuttgart.
1. Ph.D. Thesis (1990) Mikrobielle Produktion von 2,3-Butandiol durch Enterobacter aerogenes in kontinuierlicher Kultur: Quantitative Analyse und Prozessoptimierung. Technische Universität Braunschweig.
C. Proceedings and Extended Conference Abstracts
1. B. Kumar, M. D'Silva and A.-P. Zeng (2007) Modularity analysis of integrated molecular networks of Escherichia coli. Proceedings of the 2nd. Conference Foundations of systems Biology in Engineering. Stuttgart, Germany. Pp. 89-94.
2. Bharani Kumar, Hong-Wu Ma and>A.-P. Zeng (2005) An integrated interaction network of Escherichia Coli. Proceedings FOSBE 2005 (Foundations of systems Biology in Engineering), University of California , Santa Barbara, August 7-10. pp 107-110.
3. A.-P. Zeng , Sun J, Wang W, Hartlep M, Deckwer WD.: Use of genomic, proteomic and metabolic data and mathematic modeling for a system analysis of glycerol bioconversion to 1,3-propanediol . In Proceedings of 3rd International Conference on Systems Biology. E. Aurell, J. Elf and J. Jeppsson, editors. Karolinska Institutet, Stockholm. 2002: 54-55.
4. W. Wang, J. Sun, M. Hartlep, A.-P. Zeng und W.-D. Deckwer (2002) Proteomics und Bioinformatik-Tools zur Prozessanalyse der 1,3-Propandiolproduktion in Klebsiella pneumoniae. Chem.-Ing. Tech. 74, 704.
5. M. Hartlep und A.-P. Zeng (2002) Fedbatch-Verfahren für die mikrobielle Herstellung von 1,3-Propandiol in Klebsiella pneumoniae und Clostridium butyricum. Chem.-Ing. Tech. 74, 663.
6. J.-X. Bi, C. Beer, M. Wirth und A.-P. Zeng (2002) Entwicklung und dynamische Analyse von GFP-Expressionsystemen als Biomarker für die Genexpression in verschiedenen Animalzelllinien. Chem.-Ing. Tech. 74, 693.
7. W. Sabra, H. Ma, W. Wang, E.-J. Kim und A.-P. Zeng (2002) Rekonstruktion und Simulation des metabolischen Netzwerks von Pseudomonas aeruginosa für die Bildung von Virulenzfaktoren. Chem.-Ing. Tech. 74, 688.
8. A.-P. Zeng , Ma HW.: System structure analysis of metabolic networks constructed from genome data. In Proceedings of 3rd International Conference on Systems Biology. E. Aurell, J. Elf and J. Jeppsson, editors. Karolinska Institutet, Stockholm. 2002: 238-239.
9. Sun, J, van den Heuvel, J and A.-P. Zeng (2001) Reconstruction of metabolic and regulatory networks of Klebsiella pneumoniae from genome data. Proceedings of the German Conference on Bioinformatics. E. Wingender, R. Hofestädt and I. Liebich (Eds.), Braunschweig, pp: 227-228.
10. K. Jung, A.-P. Zeng and W.-D. Deckwer (2000) Physiologische und enzymatische Charakterisierung der 1,3-Propandiol-Gewinnung aus Glycerin mit Clostridium butyricum. In: Schriftenreihe " Nachwachsende Rohstoffe" Band 15: Biokonversion nachwachsender Rohstoffe. Landwirtschaftsverlag, Münster. pp: 244-252.
11. J. Modak, W.-D. Deckwer and A.-P. Zeng (2000) System Dynamic Behavior of Eucaryotic Multienzyme Pyruvate Dehydrogenase Complex under In Vivo Conditions. Proceedings of the First International Conference of Systems Biology, 14-16 November 2000, Tokyo .
12. A.-P. Zeng and W.-D. Deckwer (1997) Recent progress in the study of Stoichiometry, Kinetics and Regulation of Metabolism and Growth of Animal Cell Cultures. In: Z. Shen, F. Ouyang, J.T. Yu and Z.A. Cao (eds.) Biochemical Engineering: Marching toward the Century of Biotechnoilogy.Tsinghua University Press, Beijing . 146-152.
13. A.-P. Zeng , K. Menzel, K. Ahrens, H. Biebl, J. van den Heuvel and W.-D. Deckwer (1997) Quantification of metabolic pathways and fluxes for metabolic engineering of glycerol conversion to 1,3-propanediol. In: Z. Shen, F. Ouyang, J.T. Yu and Z.A. Cao (eds.) Biochemical Engineering: Marching toward the Century of Biotechnoilogy.Tsinghua University Press, Beijing . 267-271.
14. H. Biebl and A.-P. Zeng (1995) Role of pH and limiting factors in the glycerol fermentation of Klebsiella pneumoniae. Proceedings of Ninth Forum for Applied Biotechnology. Gent , Belgium , September 27-29, 1995 . pp 1927-1932.
15. A.-P. Zeng , R. Wagner, V. Jäger, B. Anspach, U. Rinas and W.-D. Deckwer (1994) Integrated bioprocess development. In: Teo, W.K., Yap , M.G.S. and Oh, S.K.W. (eds.) Better living through innovative biochemical engineering. Continental Press , Singapore : 364-368.
16. A.-P. Zeng , A. Ross and W.-D. Deckwer (1990) A method to estimate the P/O ratio and YATP of a facultative anaerobe in continuous culture. In: Reuss/Knackmuss/Chmiel/Gilles (eds.) Biochemical Engineering - Stuttgart, Gustav Fischer Verlag. 1990, pp: 381-384.