Prof. Dr.-Ing. Irina Smirnova

 

Institut für Thermische Verfahrenstechnik
Technische Universität Hamburg

Eißendorfer Str. 38(O)
21073 Hamburg

 

Tel: +49 40/42878-3240
smirnova@tuhh.de
Website


THEMEN

– Bioraffinerie

– Nanoporöse Materialien

– Molekulare Methoden für Trennprozesse

TECHNIKEN UND APPARATIVE AUSSTATTUNG

– Hochdruckbehälter/Sichtzellen von 10ml-4l

– Stickstoffsorption (BET)

– High Performance Liquid Chromatography

– UV/Vis Photometer

– Gaschromatographie

– Kurzwegdestillation

– Freisetzungsanlage nach EU

– Analytische Chromatographie mit überkritischen Gasen (SFC)

– Präparative überkritische Fluidchomatographie (Säule: 30 mm ID, max. 450 mm Länge)

– Überkritische Simulated Moving Bed Chromatography (8 Säulen: 30 mm ID, max. 190 mm Länge)

– Anlagen zur Herstellung von Aerogelen bis 25 Liter (T bis 200°C, P bis 300 bar)

– Kolonnen zur überkritischen Extraktion

– Soxhlet Extraktion

– Karl-Fischer Titration

– Adsorption

– Extraktions- und Rektifikationskolonnen (Normaldruck)

AKTUELLE PROJEKTE
AKTUELLE PUBLIKATIONEN (SCOPUS)

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Racheva, R., Rahlf, A.F., Wenzel, D., Müller, C., Kerner, M., Luinstra, G.A., Smirnova, I.: Aqueous food-grade and cosmetic-grade surfactant systems for the continuous countercurrent cloud point extraction. (2018) Separation and Purification Technology, 202, pp. 76-85.

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Sashkina, K.A., Gurikov, P.A., Ayupov, A.B., Smirnova, I., Parkhomchuk, E.V.: Zeolite/silica aerogel composite monoliths and microspheres. (2018) Microporous and Mesoporous Materials, 263, pp. 106-112.

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Veres, P., Sebők, D., Dékány, I., Gurikov, P., Smirnova, I., Fábián, I., Kalmár, J.: A redox strategy to tailor the release properties of Fe(III)-alginate aerogels for oral drug delivery. (2018) Carbohydrate Polymers, 188, pp. 159-167.

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Gerlach, T., Ingram, T., Sieder, G., Smirnova, I.: Modeling the solubility of CO2 in aqueous methyl diethanolamine solutions with an electrolyte model based on COSMO-RS. (2018) Fluid Phase Equilibria, 461, pp. 39-50.

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Reynolds, W., Smirnova, I.: Hydrothermal flow-through treatment of wheat straw: Coupled heat and mass transfer modeling with changing bed properties. (2018) Journal of Supercritical Fluids, 133, pp. 625-639.

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Koneva, A.S., Ritter, E., Anufrikov, Y.A., Lezov, A.A., Klestova, A.O., Smirnova, N.A., Safonova, E.A., Smirnova, I.: Mixed aqueous solutions of nonionic surfactants Brij 35/Triton X-100: Micellar properties, solutes' partitioning from micellar liquid chromatography and modelling with COSMOmic. (2018) Colloids and Surfaces A: Physicochemical and Engineering Aspects, 538, pp. 45-55.

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Gurikov, P., Smirnova, I.: Amorphization of drugs by adsorptive precipitation from supercritical solutions: A review. (2018) Journal of Supercritical Fluids, 132, pp. 105-125.

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Ritter, E., Smirnova, I.: Continuous Countercurrent Extractive Biocatalysis in Aqueous Surfactant Two-phase Systems. (2018) Chemie-Ingenieur-Technik, . Article in Press.

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Smirnova, I., Gurikov, P.: Aerogel production: Current status, research directions, and future opportunities. (2018) Journal of Supercritical Fluids, . Article in Press.

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Gerlach, T., Müller, S., Smirnova, I.: Development of a COSMO-RS based model for the calculation of phase equilibria in electrolyte systems. (2018) AIChE Journal, 64 (1), pp. 272-285.

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Rigacci, A., Budtova, T., Smirnova, I.: Aerogels: a fascinating class of materials with a wide potential of application fields. (2017) Journal of Sol-Gel Science and Technology, pp. 1-2. Article in Press.

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Kazan, A., Heymuth, M., Karabulut, D., Akay, S., Yildiz-Ozturk, E., Onbas, R., Muderrisoglu, C., Sargin, S., Heils, R., Smirnova, I., Yesil-Celiktas, O.: Formulation of organic and inorganic hydrogel matrices for immobilization of β-glucosidase in microfluidic platform. (2017) Engineering in Life Sciences, 17 (7), pp. 714-722.

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Smirnova, I., Gurikov, P.: Aerogels in chemical engineering: Strategies toward tailor-made aerogels. (2017) Annual Review of Chemical and Biomolecular Engineering, 8, pp. 307-334.

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Kühn, S., Sluyter, G., Christlieb, M.-A., Heils, R., Stöbener, A., Kleber, J., Smirnova, I., Liese, A.: In Situ Separation of the Chiral Target Compound (S)-2-Pentanol in Biocatalytic Reactive Distillation. (2017) Industrial and Engineering Chemistry Research, 56 (22), pp. 6451-6461.

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Schmidt, L.M., Mthembu, L.D., Reddy, P., Deenadayalu, N., Kaltschmitt, M., Smirnova, I.: Levulinic acid production integrated into a sugarcane bagasse based biorefinery using thermal-enzymatic pretreatment. (2017) Industrial Crops and Products, 99, pp. 172-178.

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Akay, S., Heils, R., Trieu, H.K., Smirnova, I., Yesil-Celiktas, O.: An injectable alginate-based hydrogel for microfluidic applications. (2017) Carbohydrate Polymers, 161, pp. 228-234.

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Wierschem, M., Schlimper, S., Heils, R., Smirnova, I., Kiss, A.A., Skiborowski, M., Lutze, P.: Pilot-scale validation of Enzymatic Reactive Distillation for butyl butyrate production. (2017) Chemical Engineering Journal, 312, pp. 106-117.

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Ghafar, A., Gurikov, P., Subrahmanyam, R., Parikka, K., Tenkanen, M., Smirnova, I., Mikkonen, K.S.: Mesoporous guar galactomannan based biocomposite aerogels through enzymatic crosslinking. (2017) Composites Part A: Applied Science and Manufacturing, 94, pp. 93-103.

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Kehili, M., Kammlott, M., Choura, S., Zammel, A., Zetzl, C., Smirnova, I., Allouche, N., Sayadi, S.: Supercritical CO2 extraction and antioxidant activity of lycopene and β-carotene-enriched oleoresin from tomato (Lycopersicum esculentum L.) peels by-product of a Tunisian industry. (2017) Food and Bioproducts Processing, 102, pp. 340-349.

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Kazan, A., Heymuth, M., Karabulut, D., Akay, S., Yildiz-Ozturk, E., Onbas, R., Muderrisoglu, C., Sargin, S., Heils, R., Smirnova, I., Yesil-Celiktas, O.: Formulation of organic and inorganic hydrogel matrices for immobilization of β-glucosidase in microfluidic platform. (2017) Engineering in Life Sciences, . Article in Press.

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Kirsch, C., Surendran, S., Smirnova, I.: Pressure Effects on Lignocellulose-Degrading Enzymes. (2016) Chemical Engineering and Technology, 39 (4), pp. 786-790.

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Gurikov, P., Kolnoochenko, A., Golubchikov, M., Menshutina, N., Smirnova, I.: A synchronous cellular automaton model of mass transport in porous media. (2016) Computers and Chemical Engineering, 84, pp. 446-457.

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Kirsch, C., Surendran, S., Smirnova, I.: Pressure Effects on Lignocellulose-Degrading Enzymes. (2016) Chemical Engineering and Technology, . Article in Press.

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Smirnova, I.: Aerogels: Current status and challenges for the future. (2015) Journal of Supercritical Fluids, 106, p. 1.

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Antonyuk, S., Heinrich, S., Gurikov, P., Raman, S., Smirnova, I.: Influence of coating and wetting on the mechanical behaviour of highly porous cylindrical aerogel particles. (2015) Powder Technology, 285, pp. 34-43.

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Reynolds, W., Singer, H., Schug, S., Smirnova, I.: Hydrothermal flow-through treatment of wheat-straw: Detailed characterization of fixed-bed properties and axial dispersion. (2015) Chemical Engineering Journal, 281, pp. 696-703.

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Yordanova, D., Smirnova, I., Jakobtorweihen, S.: Molecular modeling of triton X micelles: Force field parameters, self-assembly, and partition equilibria. (2015) Journal of Chemical Theory and Computation, 11 (5), pp. 2329-2340.

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García-González, C.A., Jin, M., Gerth, J., Alvarez-Lorenzo, C., Smirnova, I.: Polysaccharide-based aerogel microspheres for oral drug delivery. (2015) Carbohydrate Polymers, 117, pp. 797-806.

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Selmer, I., Kleemann, C., Kulozik, U., Heinrich, S., Smirnova, I.: Development of egg white protein aerogels as new matrix material for microencapsulation in food. (2015) Journal of Supercritical Fluids, . Article in Press.

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Martins, M., Barros, A.A., Quraishi, S., Gurikov, P., Raman, S.P., Smirnova, I., Duarte, A.R.C., Reis, R.L.: Preparation of macroporous alginate-based aerogels for biomedical applications. (2015) Journal of Supercritical Fluids, . Article in Press.

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Raman, S.P., Gurikov, P., Smirnova, I.: Hybrid alginate based aerogels by carbon dioxide induced gelation: Novel technique for multiple applications. (2015) Journal of Supercritical Fluids, . Article in Press.

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Pesci, L., Glueck, S.M., Gurikov, P., Smirnova, I., Faber, K., Liese, A.: Biocatalytic carboxylation of phenol derivatives: Kinetics and thermodynamics of the biological Kolbe-Schmitt synthesis. (2015) FEBS Journal, . Article in Press.

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Antonyuk, S., Heinrich, S., Gurikov, P., Raman, S., Smirnova, I.: Influence of coating and wetting on the mechanical behaviour of highly porous cylindrical aerogel particles. (2015) Powder Technology, . Article in Press.

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Quraishi, S., Martins, M., Barros, A.A., Gurikov, P., Raman, S.P., Smirnova, I., Duarte, A.R.C., Reis, R.L.: Novel non-cytotoxic alginate-lignin hybrid aerogels as scaffolds for tissue engineering. (2014) Journal of Supercritical Fluids, . Article in Press.

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Gurikov, P., Raman, S.P., Weinrich, D., Fricke, M., Smirnova, I.: A novel approach to alginate aerogels: Carbon dioxide induced gelation. (2015) RSC Advances, 5 (11), pp. 7812-7818.

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Glembin, P., Racheva, R., Kerner, M., Smirnova, I.: Micelle mediated extraction of fatty acids from microalgae cultures: Implementation for outdoor cultivation. (2014) Separation and Purification Technology, 135, pp. 127-134.

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Perez-Cantu, L., Liebner, F., Smirnova, I.: Preparation of aerogels from wheat straw lignin by cross-linking with oligo(alkylene glycol)-α,ω-diglycidyl ethers. (2014) Microporous and Mesoporous Materials, 195, pp. 303-310.

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Jakobtorweihen, S., Zuniga, A.C., Ingram, T., Gerlach, T., Keil, F.J., Smirnova, I.: Predicting solute partitioning in lipid bilayers: Free energies and partition coefficients from molecular dynamics simulations and COSMOmic. (2014) Journal of Chemical Physics, 141 (4), art. no. 045102.

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Storm, S., Jakobtorweihen, S., Smirnova, I.: Solubilization in mixed micelles studied by molecular dynamics simulations and COSMOmic. (2014) Journal of Physical Chemistry B, 118 (13), pp. 3593-3604.

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Starbird, R., García-González, C.A., Smirnova, I., Krautschneider, W.H., Bauhofer, W.: Synthesis of an organic conductive porous material using starch aerogels as template for chronic invasive electrodes. (2014) Materials Science and Engineering C, 37 (1), pp. 177-183.

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Storm, S., Aschenbrenner, D., Smirnova, I.: Reverse micellar extraction of amino acids and complex enzyme mixtures. (2014) Separation and Purification Technology, 123, pp. 23-34.

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Safonova, E.A., Mehling, T., Storm, S., Ritter, E., Smirnova, I.V.: Partitioning equilibria in multicomponent surfactant systems for design of surfactant-based extraction processes. (2014) Chemical Engineering Research and Design, 92 (12), pp. 1840-1850.

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Wörmeyer, K., Smirnova, I.: Breakthrough measurements of CO2 through aminofunctionalised aerogel adsorbent at low partial pressure: Experiment and modeling. (2014) Microporous and Mesoporous Materials, 184, pp. 61-69.

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Men’shutina, N.V., Katalevich, A.M., Smirnova, I.: Preparation of silica-based aerogels by supercritical drying. (2014) Russian Journal of Physical Chemistry B, 8 (7), pp. 973-979.

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Heils, R., Niesbach, A., Wierschem, M., Claus, D., Soboll, S., Lutze, P., Smirnova, I.: Integration of enzymatic catalysts in a continuous reactive distillation column: Reaction kinetics and process simulation. (2014) Industrial and Engineering Chemistry Research, 53 (50), pp. 19612-19619.

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Cumana, S., Ardao, I., Zeng, A.-P., Smirnova, I.: Glucose-6-phosphate dehydrogenase encapsulated in silica-based hydrogels for operation in a microreactor. (2014) Engineering in Life Sciences, 14 (2), pp. 170-179.

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Heils, R., Hilterhaus, L., Liese, A., Smirnova, I.: Reactive distillation with biocatalytic coatings for structured packings. (2014) Process Development Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future, pp. 152-153.