Publication list Prof. Dr. Dr. h.c. G. Antranikian




229. Busch P., Suleiman M., Schäfers C., Antranikian G. (2021) A multi‑omic screening approach for the discovery of thermoactive glycoside hydrolases. Extremophiles



228. Suleiman M., Krüger A. and Antranikian G. (2020) Biomass‑degrading glycoside hydrolases of archaeal origin. Biotechnology for Biofuels 13, 153.

227. Krüger A., Schäfers C., Busch P. and Antranikian G. (2020) Digitalization in microbiology – Paving the path to sustainable circular bioeconomy. New Biotechnology, 59, 88-96.

226. Schröder C., Burkhardt C. and Antranikian G (2020) What we learn from extremophiles. ChemTexts 6, 8.



225. Suleiman M., Schröder C., Kuhn M., Simon A., Stahl A., Frerichs H. and Antranikian G. (2019) Microbial biofilm formation and degradation of octocrylene, a UV absorber found in sunscreen. Communications biology, 2(1), 1-5.

224. Schröder C., Eixenberger D., Suleiman M., Schäfers C. and Antranikian G. (2019) Characterization of an extremely thermo-active archaeal β-glucosidase and its activity towards glucan and mannan in concert with an endoglucanase. Applied Microbiology and Biotechnology.

223. Burkhardt C., Schäfers C., Claren J., Schirrmacher G. and Antranikian G. (2019) Comparative Analysis and Biochemical Characterization of Two Endo-β-1, 3-Glucanases from the Thermophilic Bacterium Fervidobacterium sp. Catalysts, 9(10), 830.

222. Klippel B., Blank S., Janzer V. A., Piascheck H., Moccand C., Bel-Rhlid R. and Antranikian G. (2019) Characterization of a thermoactive endoglucanase isolated from a biogas plant metagenome. Extremophiles.

221. Suleiman M., Klippel B., Busch P., Schäfers C., Moccand C., Bel-Rhlid R., Palzer S. and Antranikian G. (2019) Enrichment of anaerobic heterotrophic thermophiles from four Azorean hot springs revealed different community composition and genera abundances using recalcitrant substrates. Extremophiles. doi:10.1007/s00792-019-01079-7



220. Suleiman M., Schröder C., Klippel B., Schäfers C., Krüger A. and Antranikian G. (2018) Extremely thermoactive archaeal endoglucanase from a shallow marine hydrothermal vent from Vulcano Island. Applied Microbiology and Biotechnology,

219. Schröder C., Burkhardt C., Busch P., Schirrmacher G., Claren J. and Antranikian G. (2018) Characterization of a Theme C Glycoside Hydrolase Family 9 Endo-Beta-Glucanase from a Biogas Reactor Metagenome. The Protein Journal, 37

218. Krüger A., Schäfers C., Schröder C., Antranikian G. (2018) Towards a sustainable biobased industry – Highlighting the impact of extremophiles, New Biotechnology; Volume 40, Part A, pp. 144-153; doi:



217. Antranikian G., Suleiman M., Schäfers C., Adams M.W.W., Bartolucci S., Blamey J.M., Birkeland N.K., Bonch-Osmolovskaya E., da Costa M.S., Cowan D., Danson M., Forterre P., Kelly R., Ishino Y., Littlechild J., Moracci M., Noll K., Oshima T., Robb F., Rossi M., Santos H., Schönheit P., Sterner R., Thauer R., Thomm M., Wiegel J., Stetter K.O. (2017) Diversity of bacteria and archaea from two shallow marine hydrothermal vents from Vulcano Island, Extremophiles. doi: 10.1007/s00792-017-0938-y

216. Elleuche S., Krull A., Lorenz U., Antranikian G. (2017) Parallel N- and C-Terminal Truncations Facilitate Purification and Analysis of a 155-kDa Cold-Adapted Type-I Pullulanase. Protein J. doi:10.1007/s10930-017-9703-4

215. Schäfers C., Blank S., Wiebusch S., Elleuche S., Antranikian G. (2017) Complete genome sequence of Thermus brockianus GE-1 reveals key enzymes of xylan/xylose metabolism. Standards in Genomic Sciences.2017;12:22. doi: 10.1186/s40793-017-0225-7

214. Elleuche S., Schröder C., Stahlberg N., Antranikian G. (2017) "Boiling Water is not too Hot for Us!" - Preferred Living Spaces of Heat-Loving Microbes. Front Young Minds.5:1

213. Antranikian G. (2017) International Conference on Extremophiles 2016. Extremophiles. 2017 Jan;21(1):1-2. doi: 10.1007/s00792-016-0906-y

212. Schröder C., Janzer V.A., Schirrmacher G., Claren J., Antranikian G. (2017) Characterization of two novel heat-active α-galactosidases from thermophilic bacteria. Extremophiles. 2017 Jan;21(1):85-94. doi: 10.1007/s00792-016-0885-z



211. Elleuche S., Esselun P., Grote R., Klippel B., Krüger A., Liese A., Ostrop M., Schäfers C., Schröder C., Antranikian G. (2016) 8th International Congress on Biocatalysis (Biocat2016), Hamburg, Germany, 28 August–1 September, 2016 (Meeting Report). Catalysts 2016, 6, 160; doi:10.3390/catal6100160

210. Hilterhaus, L., Liese, A., Kettling, U., Antranikian, G. - ed. (2016) Applied Biocatalysis: From Fundamental to Industrial Applications. Wiley-VCH Verlag GmbH & Co. KGaA

209. Antranikian, G. (2016) Foreword. In: Rampelotto PH (Ed.) Grand Challenges in Biology and Biotechnology Vol. 1: Biotechnology of Extremophiles. Springer Verlag, Berlin, Heidelberg, New York, Tokyo; pp. vii-viii

208. Ibrahim, A., El-Toni, A., Al-Salamah, A., Almaary, K., El-Tayeb, M., Elbadawi, Y., Antranikian, G. (2016) Development of novel robust nanobiocatalyst for detergents formulations and the other applications of alkaline protease. Bioprocess. Biosyst. Eng. 39:793-805

207. Rizk, M., Antranikian, G., Elleuche, S. (2016) Influence of linker length variations on the biomass-degrading performance of heat-active enzyme chimeras. Mol. Biotechnol. 58:268-279

206. Ibrahim, A., Al-Salamah, A., El-Toni, A., Almaary, K., El-Tayeb, M., Elbadawi, Y., Antranikian, G. (2016) Enhancement of alkaline protease activity and stability via covalent immobilization onto hollow core-mesoporous shell silica nanospheres. Int. J. Mol. Sci. 17:184

205. Elleuche, S., Schröder, C., Antranikian, G. (2016) Lipolytic Extremozymes from Psychro- and (Hyper-)Thermophilic Prokaryotes and their Potential for Industrial Applications. In: Rampelotto PH (Ed.) Grand Challenges in Biology and Biotechnology Vol. 1: Biotechnology of Extremophiles. Springer Verlag, Berlin, Heidelberg, New York, Tokyo; pp. 351-374

204. Krüger, A., Elleuche, S., Sahm, K., Antranikian, G. (2016) Robust biocatalysts - routes to new diversity. In: Hilterhaus, L., Liese, A., Kettling, U., Antranikian, G. (Eds.) Applied Biocatalysis: From Fundamental Science to Industrial Applications. Wiley-VCH Verlag GmbH; pp. 31-51


203. Ibrahim, A., Al-Salamah, A., El-Badawi, Y., El-Tayeb, M., Antranikian, G. (2015) Detergent-, solvent- and salt-compatible thermoactive alkaline serine protease from halotolerant alkaliphilic Bacillus sp. NPST-AK15: Purification and characterization. Extremophiles 19:961-971

202. Sabra, W., Röske, I., Sahm, K., Antranikian, G., Zeng, A-P. (2015) High-temperature biogas reactors to treat stillage from an industrial bioethanol process: Metabolic and microbial characterization. Eng. Life Sci. 15:743-750

201. Elleuche, S., Schäfers, C., Blank, S., Schröder, C., Antranikian, G. (2015) Exploration of extremophiles for high temperature biotechnological processes. Curr. Opin. Microbiol. 25C:113-119

200. Schröder, C., Blank, S., Antranikian, G. (2015). First glycoside hydrolase family 2 enzymes from Thermus antranikianii and Thermus brockianus with β-glucosidase activity. Front. Bioeng. Biotechnol. 3:76. doi: 10.3389/fbioe.2015.00076

199. Elleuche, S., Qoura, F., Lorenz, U., Rehn, T., Brück, T., Antranikian, G. (2015) Cloning, expression and characterization of the recombinant cold-active type-I pullulanase from Shewanella arctica. Journal of Molecular Catalysis B: Enzymatic 116:70-77

198. Qoura, F., Kassab, E., Reiße, S., Antranikian, G., Brück, T. (2015) Characterization of a new, recombinant thermo-active subtilisin-like serine protease derived from Shewanella arctica. Journal of Molecular Catalysis B: Enzymatic 116:16-23

197. Schäfers, C., Elleuche, S., Antranikian, G. (2015) Biochemical Properties and Applications of Heat-active Biocatalysts. In: Li F-L (Ed.), Thermophilic Microorganisms. Caister Academic Press; pp. 47-90

196. Rizk, M., Elleuche, S., Antranikian, G. (2015) Generating bifunctional fusion enzymes composed of heat-active endoglucanase (Cel5A) and endoxylanase (XylT). Biotechnol Lett 37:139-145


195. Antranikian, G., Bonch-Osmolovskaya, E., Atomi, H., Oren, A., Adams, M.W., Santos, H. (2014) Special Issue: International conference on extremophiles 2014 - Editorial. Extremophiles 18:789-790

194. Qoura, F., Elleuche, S., Brück, T., Antranikian, G. (2014) Purification and characterization of a cold-adapted pullulanase from a psychrophilic bacterial isolate. Extremophiles 18:1095-1102

193. Klippel, B., Sahm, K., Basner, A., Wiebusch, S., John, P., Lorenz, U., Peters, A., Abe, F., Takahashi, K., Kaiser, O., Goesmann, A., Jaenicke, S., Grote, R., Horikoshi, K., Antranikian, G. (2014) Carbohydrate-active enzymes identified by metagenomic analysis of deep-sea sediment bacteria. Extremophiles 18:853-863

192. Röske, I., Sabra , W., Nacke , H., Daniel , R., Zeng, A-P., Antranikian , G., Sahm, K. (2014) Microbial community composition and dynamics in high temperature biogas reactors using industrial bioethanol waste as substrate. Appl. Microbiol. Biotechnol. 98:9095-9106

191. Qoura, F., Brueck, T., Antranikian, G. (2014) The psychrophile Shewanella arctica sp. nov: A new source of industrially important enzyme systems. JSM Biotechnol. Biomed. Eng. 2(1):1026

190. Blank, S., Schröder, C., Schirrmacher, G., Reisinger, C., Antranikian, G. (2014) Biochemical characterization of a recombinant xylanase from Thermus brockianus, suitable for biofuel production. JSM Biotechnol. Biomed. Eng. 2(1):1027

189. Elleuche, S., Schröder, C., Sahm, K., Antranikian, G. (2014) Extremozymes – biocatalysts with unique properties from extremophilic microorganisms. Curr. Opin. Biotechnol. 29C:116-123

188. Schröder, C., Elleuche, S., Blank, S., Antranikian, G. (2014) Characterization of a heat-active archaeal beta -glucosidase from a hydrothermal spring metagenome. Enzyme Microb. Technol. 57:48-54

187. Basner, A., Antranikian, G. (2014) Isolation and biochemical characterization of a glucose dehydrogenase from a hay infusion metagenome. PLOSone: e85844

186. Elleuche, S., Fodor, K., von der Heyde, A., Klippel, B., Wilmanns, M., Antranikian, G. (2014) Group III-alcohol dehydrogenase from Pectobacterium atrosepticum: insights into enzymatic activity and organization of the metal-ion containing region. Appl. Microbiol. Biotechnol. 98:4041-4051


185. Acevedo-Rocha, C. G., Hoesl, M. G., Nehring, S., Royter, M., Wolschner, C., Wiltschi, B., Antranikian, G., Budisa, N. (2013) Non-canonical amino acids as a useful synthetic biological tool for lipase-catalysed reactions in hostile environments. Catal. Sci. Technol. 3:1198-1201

184. Sahm, K., John, P., Nacke, H., Wemheuer, B., Grote, R., Daniel, R., Antranikian, G. (2013) High abundance of heterotrophic prokaryotes in hydrothermal springs of the Azores as revealed by a network of 16S rRNA gene-based methods. Extremophiles 17:649-662

183. Elleuche, S., Antranikian, G. (2013) Bacterial group III alcohol dehydrogenases – function, evolution and biotechnological applications. OA Alcohol 1(1):3

182. Elleuche, S., Fodor, K., Klippel, B., von der Heyde, A., Wilmanns, M., Antranikian, G. (2013) Structural and biochemical characterization of a NAD(+)-dependent alcohol dehydrogenase from Oenococcus oeni as a new model molecule for industrial biotechnology applications. Appl. Microbiol. Biotechnol. 97:8963–8975

181. Elleuche, S. , Klippel, B., von der Heyde, A., Antranikian, G. (2013) Comparative analysis of two members of the metal ion-containing group III-alcohol dehydrogenases from Dickeya zeae . Biotechnol. Lett. 35:725-733

180. Elleuche, S. , Antranikian, G. (2013) Starch-hydrolyzing enzymes from thermophiles. In: Satyanarayana T, Littlechild J, Kawarabayasi Y (Ed.), Thermophilic Microbes Environmental and Industrial Biotechnology. Springer Verlag, Berlin, Heidelberg, New York, Tokyo; pp. 509-533

179. Jabbour, D., Sorger, A., Sahm, K., Antranikian, G. (2013) A highly thermoactive and salt-tolerant α-amylase isolated from a pilot-plant biogas reactor. Appl. Microbiol. Biotechnol. 97:2971-2978


178. Maurer, K.-H., Elleuche, S., Antranikian, G. (2012) 10. Enzyme. In: Sahm, H., Antranikian, G., Stahmann, K.-P., Takors, R. – ed. Industrielle Mikrobiologie. Springer Berlin, Heidelberg, New York, Tokyo; pp.205-224.

177. Sahm, H., Antranikian, G., Stahmann, K.-P., Takors, R. – ed. (2012) Industrielle Mikrobiologie. Springer Berlin, Heidelberg, New York, Tokyo.

176. Ibrahim, A. S., Al-Salamah, A. A., El-Tayeb, M. A., Elbadawi, Y. B., Antranikian, G. (2012) A Novel Cyclodextrin Glycosyltransferase from Alkaliphilic Amphibacillus sp. NPST-10: Purification and Properties. Int. J. Mol. Sci. 13:10505-10522.

175. Rizk, M., Antranikian, G., Elleuche, S. (2012) End-to-end gene fusions and their impact on the production of multifunctional biomass degrading enzymes. Biochem. Biophys. Res. Commun. 428: 1-5

174. Elleuche, S., Sahm, K., Grote, R., Antranikian, G. (2012) Extremozyme – Neue Biokatalysatoren für die industrielle Anwendung. Biol. unserer Zeit 42: 166-173

173. Ibrahim, A. S., El-Tayeb, M. A., Elbadawi, Y. B., Al-Salamah, A. A., Antranikian, G. (2012) Hexavalent chromate reduction by alkaliphilic Amphibacillus sp. KSUCr3 is mediated by copper dependent membrane-associated Cr(VI) reductase. Extremophiles 16: 659-668

172. Jabbour, D., Klippel, B., Antranikian, G. (2012) A novel thermostable and glucose-tolerant ß-glucosidase from Fervidobacterium islandicum. Appl. Microbiol. Biotechnol. 93:1947-1956.


171. Lochner, A., Giannone, R. J., Keller, M., Antranikian, G., Graham, D. E., Hettich, R. L. (2011) Label-free quantitative proteomics for the extremely thermophilic bacterium Caldicellulosiruptor obsidiansis reveal distinct abundance patterns upon growth on cellobiose, crystalline cellulose, and switchgrass. J. Proteome Res. 10: 5302-5314.

170. Klippel, B., Lochner, A., Bruce, D. C., Davenport, K. W., Detter, C., Goodwin, L. A., Han, J., Han, S., Land, S., Mikhailova, N., Nolan, M., Pennacchio, L., Pitluck, S., Tapia, R., Woyke, T., Wiebusch, S., Basner, A., Abe, F., Horikoshi, K., Keller, M., Antranikian, G. (2011) Complete genome sequence of the marine, cellulose and xylan degrading bacterium Glaciecola sp. 4H-3-7+YE-5. J. Bacteriol. 193: 4547-4548.

169. Klippel, B., Lochner, A., Bruce, D. C., Davenport, K. W., Detter, C., Goodwin, L. A., Han, J., Han, S., Hauser, L., Land, M. L., Nolan, M., Ovchinnikova, G., Pennacchio, L., Pitluck, S., Tapia, R., Woyke, T., Wiebusch, S., Basner, A., Abe, F., Horikoshi, K., Keller, M., Antranikian, G. (2011) Complete genome sequences of Krokinobacter sp. 4H-3-7-5 and Lacinutrix sp. 5H-3-7-4, polysaccharide-degrading members of the family Flavobacteriaceae. J. Bacteriol. 193: 4545-4546.

168. Voget, S., Klippel, B., Daniel, R., Antranikian, G. (2011) Complete Genome Sequence of Carnobacterium sp. 17-4. J. Bacteriol. 193: 3403-3404.

167. Lamosa, P., Mingote, A. I., Groudieva, T., Klippel, B., Egorova, K., Jabbour, D., Santos, H., Antranikian, G. (2011) Gluconeotrehalose is the principal organic solute in the psychrotolerant bacterium Carnobacterium strain 17-4. Extremophiles 15: 463-472.

166. Lochner, A., Giannone, R. J., Rodriguez Jr., M., Shah, M- B., Mielenz, J. R., Keller, M., Antranikian, G., Graham, D. E., Hettich, R. L. (2011) Use of Label-free quantitative proteomics to distinguish the secreted cellulolytic systems of Caldicellulosiruptor bescii and Caldicellulosiruptor obsidiansis. Appl. Environ. Microbiol. 77:4042-4054.

165. Elleuche, S., Piascheck, H., Antranikian, G. (2011) Fusion of the OsmC domain from esterase confers thermolability to the cold-active xylanase Xyn8 from Pseudoalteromonas arctica. Extremophiles 15:311-317.

164. Ingram, T., Wörmeyer, K., Lima, J., C., I., Bockemühl, V., Antranikian, G., Brunner, G., Smirnova, I. (2011) Comparison of Different Pretreatment Methods for Lignocellulosic Materials. Part I: Conversion of Rye Straw to Valuable Products. Bioresource Technology 102: 5221-5228.

163. Raczynska, J., Vorgias, C. E., Antranikian, G., Rypniewski, W. (2011) Crystallographic analysis of a thermoactive nitrilase. J. Structural Biol. 173: 294- 302.

162. Klippel, B., Antranikian, G. (2011) Lignocellulose Converting Enzymes from Thermophiles. In: Extremophiles Handbook, ed. Horikoshi, K., Antranikian, G., Bull, A. T., Robb, F. T., Stetter, K. O. Springer Vol. 1:443-474.

161. Horikoshi, K., Antranikian, G., Bull, A. T., Robb, F. T., Stetter, K. O. – eds. (2011) Extremophiles Handbook. Springer Reference, Vol. 1 and 2.

160. Hoesl, M., Acevedo-Rocha, C. G., Nehring, S., Royter, M., Wolschner, C., Wiltschi, B., Budisa, N., Antranikian, G. (2011) Lipase congeners designed by genetic code engineering. ChemCatChem 3:213-221.


159. Antranikian, G, Bornscheuer, UT, Liese, A (2010) Highlights in Biocatalysis. ChemCatChem 2:879-880.

158. Merkel, L., Schauer, M., Antranikian, G., Budisa, N. (2010) Parallel incorporation of different fluorinated amino acids: On the way to “Teflon” proteins. ChemBioChem 11, 1505-1507.

157. Al Khudary, R., Venkatachalam, R., Katzer, M., Elleuche, S., Antranikian, G. (2010) A cold- adapted esterase of a novel marine isolate, Pseudoalteromonas arctica : gene cloning, enzyme purification and characterization. Extremophiles 14:273-285.


156. Ingram, T., Rogalinski, T., Bockemühl, V., Antranikian, G., Brunner, G. (2009) Semi-continuous liquid hot water pretreatment of rye straw. J. of Supercritical fluids 48:238-246.

155. Royter, M., Schmidt, M., Elend, C., Höbenreich, H. Schäfer, T., Bornscheuer, U.T., Antranikian, G. (2009) Thermostable lipases from the extreme thermophilic anaerobic bacteria Thermoanaerobacter thermohydrosulfuricus SOL1 and Caldanaerobacter subterraneus subsp. tencongensis . Extremophiles 13:769-783.

154. Antranikian, G., Ruepp, A., Gordon, P.M.K., Ballschmiter, M., Zibat, A., Stark, M., Sensen, C.W., Frishman, D., Liebl, W., Klenk, H.-P. (2009) Rapid Access to Genes of Biotechnologically Useful Enzymes by Partial Genome Sequencing: The Thermoalkaliphile Anaerobranca gottschalkii. J. Mol. Microbiol. Biotechnol. 16:81-90.


153. Antranikian, G. (2008) Extremophiles and biotechnology. In press.

152. Weber, D.G., Sahm, K., Polen, T., Wendisch, V.F., Antranikian, G. (2008) Oligonucleotide microarrays for the detection and identification of viable beer spoilage bacteria. JAM ISSN 1364-5072.

151. Hilterhaus, L., Minow, B., Müller, J., Berheide, M., Quitmann, H., Katzer, M., Antranikian, G., Zeng, A.P., Liese, A. (2008) Practical application of different enzymes immobilized on sepabeds. Bioprocess Biosyst Eng 31(3):163-71.

150. Al Khudary, R., Stößer, N.I., Qoura, F., Antranikian, G. (2008) Pseudoalteromonas arctica sp. nov., a novel aerobic, psychrotolerant, marine bacterium isolated from Spitzbergen. IJSEM 58:2018- 2024.

149. Hess, M., Katzer, M., Antranikian, G., (2008) Extremely thermostable esterases from the thermoacidophilic euryarchaeon Picrophilus torridus . Extremophiles 12:351-364.

148. Antranikian, G. (2008) Thermoacidophiles and their protein adaptation to low pH and high temperature. In: Protein adaptation in extremophiles. eds. Siddiqui, S., Thomas, T. Nova Science Publ. New York. ISBN 9781604560190.

147. Antranikian, G. (2008) Industrial relevance of thermophiles and their enzymes. In: Thermophiles – Biology and Technology at high temperatures. eds. Robb, F. et al., CRC Press, Boca Raton: Taylor & Francis. p.113-160.

146. Robb, F., Antranikian, G., Grogan, D., Driessen, A. (eds.) (2008) Thermophiles – Biology and Technology at high temperatures. CRC Press, Boca Raton: Taylor & Francis. ISBN 9780849392146.

145. Hess, M., Antranikian, G. (2008) Archaeal alcohol dehydrogenase active at increased temperatures and in the presence of organic solvents. Appl. Microbiol. Biotechnol. 77(5):1003-13.


144. Dock, C, Hess, M., Antranikian, G. (2007) A thermoactive glucoamylase with biotechnological relevance from the thermoacidophilic euryarchaeon Thermoplasma acidophilum . Appl. Microbiol. Biotechnol. 78(1):105-14.

143. Borchert, M., Nielsen, P., Graeber, I., Kaesler, I., Szewzyk, U., Paper, T., Antranikian, G., Schäfer, T. (2007) Bacillus plakortidis sp. nov. and Bacillus murimartini sp. nov., novel alkalitolerant members of rRNA group 6. Int. J. Syst. Evol. Microbiol. 57:2888-2893.

142. Egorova, K., Grudieva, T., Morinez, C., Kube, J., Santos, H., Da Costa, M., Antranikian, G. (2007) High yield of mannosylglycerate production by upshock fermentation and bacterial milking of trehalose-deficient mutantThermus thermophilus RQ-1. Appl. Microbiol. Biotechnol. 75(5):1039-1045.

141. Antranikian, G., Egorova, K. (2007) Extremophiles, a Unique Resource of Biocatalysts for Industrial Biotechnlology: Physiology and Biochemistry of Extremophiles, ed. by Charles Gerday and Nicolas Glansdorff. ASM Press, Washington D.C.

140. Egorova, K., Antranikian, G. (2007) Biotechnology: Archaea – Evolution, Physiology, and Molecular Biology, ed. by Roger A. Garrett and Hans-Peter Klenk. Blackwell Publ. Ltd. USA, UK, Australia.


139. Schepers, B., Thiemann, V., Antranikian, G. (2006) Characterization of a Novel Glucoamylase from the Thermoacidophilic Archaeon Picrophilus torridus Heterologously Expressed in E. coli . Eng. Life Sci. 6(3):311-317.

138. Mueller, P., Egorova, K., Vorgias, C. E., Boutou, E., Trauthwein, H., Verseck, S., Antranikian G. (2006) Cloning, overexpression and characterization of a thermoactive nitrilase from the hyperthermophilic archaeonPyrococcus abyssi . Prot Expr Purif 47:672-681.


137. Antranikian, G., Vorgias, C.E., Bertoldo, C. (2005) Extreme Environments as a Resource for Microorganisms and Novel Biocatalysts. Adv. Biochem. Engin./Biotechnol. 96:219-262.

136. Thiemann, V., Saake, B., Vollstedt, A., Schäfer, T., Puls, J., Bertoldo, C., Freudl, R., Antranikian, G. (2005) Heterologous expression and characterization of a novel branching enzyme from the thermoalkaliphilic anaerobic bacterium Anaerobranca gottschalkii . Appl. Microbiol. Biotechnol. DOI 10.1007/s00253-005-0248-7.

135. Egorova, K., Antranikian, G. (2005) Industr ial relevance of thermophilic Archaea. Current Opinion in Microbiology 8:649- 655.

134. Antranikian, G. (ed.) (2005) Angewandte Mikrobiologie, Springer- Verlag Berlin Heidelberg New York, Sept. 2005.

133. Gödde, C., Sahm, K., Brouns, S.J., Kluskens, L.D., van der Oost, J., de Vos, W.M., Antranikian, G. (2005) Cloning and expression of islandisin, a new thermostable subtilisin from Fervidobacterium islandicum , inEscherichia coli . Appl. Environ. Microbiol. 71(7):3951-3958.

132. Ballschmitter, M., Armbrecht, M., Ivanova, K., Antranikian, G., Liebl, W. (2005) AmyA, an alpha-amylase with beta-cyclodextrin-forming activity, and AmyB from the thermoalkaliphilic organism Anaerobranca gottschalkii: two alpha-amylases adapted to their different cellular localizations. Appl. Environ. Microbiol. 71(7):3709-15.

131. Deppe, U., Richnow, H.-H., Michaelis, W., Antranikian, G. (2005) Degradation of crude oil by an arctic microbial consortium. Extremophiles July 2005.


130. Groudieva, T., Kambourova, M., Yusef, H., Royter, M., Grote, R., Trinks, H., Antranikian, G. (2004) Diversity and cold-active hydrolytic enzymes of culturable bacteria associated with Arctic sea ice, Spitzbergen. Extremophiles 8:475-488.

129. Bertoldo, C., Dock, C., Antranikian, G. (2004) Thermoacidophilic Microorganisms and their Novel Biocatalysts. Eng. Life Sci., WILEY-VCH Verlag, Weinheim, Vol. 4, 6:521-532.

128. Thiemann, V., Dönges, C., Prowe, S., Sterner, R., Antranikian, G. (2004) Characterisation of a thermoalkali-stable cyclodextrin glycosyltransferase from the anaerobic thermoalkaliphilic bacterium Anaerobranca gottschalkii . Arch. Microbiol. 182: 226-235.

127. Fütterer, O., Angelov, A., Liesegang, H., Gottschalk, G., Schleper, C., Schepers, B., Dock, C., Antranikian, G., Liebl, W. (2004) Genome sequence of Picrophilus torridus and its implications for life around pH 0. Proc. Nat. Acad. Sci. USA 101: 9091-9096.

126. Egorova, K., Trauthwein, H., Verseck, S., Antranikian, G. (2004) Purification and properties of an enantioselective and thermoactive amidase from the thermophilic actinomycete Pseudonocardia thermophila . Appl. Microbiol. Biotechnol. 65: 38-45.

125. Bertoldo, C., Armbrecht, M., Becker, F., Schäfer, T., Antranikian, G., Liebl, W. (2004) Cloning, sequencing, and characterization of a heat- and alkali-stable type I pullulanase from Anaerobranca gottschalkii . Appl. Environ. Microbiol. 70: 3407-3416.

124. Vorgias, C. E., Antranikian, G. (2004) Extremophiles: pH, temperature, and salinity, p. 146-153. Alan T. Bull (ed.) Microbial Diversity and Bioprospecting, ASM Press, Washington, D.C.


123. Sánchez-Porro, C., Mellado, E., Bertoldo, C., Antranikian, G., Ventosa, A. (2003) Screening and characterization of the protease CP1 produced by the moderately halophilic bacterium Pseudoalteromonas sp. strain CP76. Extremophiles 7:221-228.

122. Linden, A., Mayans, O., Meyer-Klaucke, W., Antranikian, G., Wilmanns, M. (2003) Differential regulation of a hyperthermophilic α-amylase with a novel (Ca,Zn) two-metal center by Zinc. J. Biol. Chem., vol. 278, 11:9875-9884.

121. Groudieva, T., Grote, R. Antranikian, G. (2003) Psychromonas arctica sp. nov., a novel psychrotolerant, biofilm-forming bacterium isolated from Spitzbergen. Int. J. Syst. Environ. Microbiol. 53:539-545.


120. Serour, E., Antranikian G., (2002) Novel thermoactive glucoamylases from the thermoacidophilic Archaea Thermoplasma acidophilum , Picrophilus torridus and Picrophilus oshimae . A. van Leeuwenhoek 81:73-83.

119. Biwer, A., Antranikian, G., Heinzle, E., (2002) Enzymatic production of cyclodextrins. Appl. Microbiol. Biotechnol. 59:609-617.

118.Bertoldo, C., Grote, R., Antranikian G. (2002) Extremophiles: Life in extreme environments. Encyclop. of Environ. Microbiol. 6:1232-1237.

117. Bertoldo, C., Antranikian, G. (2002) Enzymes from extreme thermophilic and hyperthermophilic archaea and bacteria. Enzyme catalysis in organic synthesis, Drauz und Waldmann 1:313-334.

116. Kluskens, L.D., Voorhorst, W.G.B., Siezen, R.J., Schwerdtfeger, R.M., Antranikian, G., van der Oost, J., de Vos, W.M. (2002) Molecular characterization of fervidolysin, a subtilisin-like serine protease from the thermophilic bacterium Fervidobacterium pennivorans . Extremophiles 6:185-194.

115. Bertoldo, C., Antranikian, G. (2002) Starch-hydrolyzing enzymes from thermophilic archaea and bacteria. Current Opinion in Chemical Biology 6: 151-160.

114. Böhlke, K., Pisani, F.M., Rossi, M., Antranikian, G. (2002) Archaeal DNA replication: spotlight on a rapidly moving field. Extremophiles 6: 1-14.


113. Riessen, S., Antranikian, G., (2001) Isolation of Thermoanaerobacter keratinophilus sp. nov., a novel thermophilic, anaerobic bacterium with keratinolytic activity. Extremophiles 5: 399-408.

112. Kim, B.-C., Grote, R., Lee, D.-W., Antranikian, G., Pyun, Y.-R. (2001) Thermoanaerobacter yonseiensis sp. nov., a novel extremely thermophilic, xylose-utilizing bacterium that grows at up to 85°C. IJSE 51: 1539- 1548.

111. Bertoldo, C., Grote, R., Antranikian, G. (2001) Biocatalysis under extreme conditions. Biotechnology 10: 61-103.

110. Prowe, S. G., Antranikian, G. (2001) Anaerobranca gottschalkii sp. nov., a novel thermoalkaliphilic bacterium that grows anaerobically at high pH and temperature. IJSE 51: 457-465.


109. Bertoldo, C., Antranikian, G. (2000) Amylolytic enzymes from hyperthermophiles. Methods in Enzymology. 330:269-289.

108. Lebbink, J.H.G., Bertoldo, C., Tibbelin, G., Andersen, J.T., Duffner, F., Antranikian, G., Ladenstein, R. (2000) Crystallization and preliminary X-ray crystallographic studies of the thermoactive pullulanase type I, hydrolyzing α-1,6 glycosidic linkages, from Fervidobacterium pennivorans Ven5. Acta Cryst. 56: 1470-1472.

107. Duffner, F., Bertoldo, C., Andersen, J.T., Wagner, K., Antranikian, G. (2000) A new thermoactive pullulanase from Desulfurococcus mucosus : Cloning, sequencing, purification, and characterization of the recombinant enzyme after expression in Bacillus subtilis . Journal of Bacteriology 182:6331-6338.

106. Feitkenhauer, H., Hebenbrock, S., Deppe, U., Märkl, H., Antranikian, G. (2001) Degradation of xenobiotics at elevated temperatures. Treatment of contaminated soil, (eds. Stegmann, Brunner, Calmano, Matz), Springer-Verlag, Berlin, pp. 365-384.

105. Annweiler, E.; Richnow, H. H.; Antranikian, G.; Hebenbrock, S; Garms, C.; Franke, S.; Francke, W.; Mich aelis, W. (2000) Naphthalene degradation and incorporation of naphthalene-derived carbon into biomass by the thermophile Bacillus thermoleovorans . Appl. Environ. Microbiol. 66: 518-523.

104. Markossian, S., Becker, P., Märkl, H., Antranikian, G. (2000) Isolation and characterization of a lipid degrading Bacillus thermoleovorans IHI-91 from an icelandic hot spring. Extremophiles 4: 365-371.

103. Böhlke, K., Pisani, F. M., Vorgias, C. E., Frey, B., Sobek, H., Rossi, M., Antranikian, G. (2000) PCR performance of the B-type DNA polymerase from the thermophilic euryarchaeon Thermococcus aggregans improved by mutations in the Y-GG/A motif. Oxford University Press. Nucleic Acids Research. Vol. 28; 20: 3910-3917.

102. Niehaus, F., Peters, A., Groudieva, T., Antranikian, G. (2000) Cloning, expression and biochemical characterisation of a unique thermostable pullulan-hydrolysing enzyme from the hyperthermophilic archaeonThermococcus aggregans . FEMS Microbiology letters 190: 23-229.

101. Vorgias, E. C., Antranikian, G. (2000) Glycosyl Hydrolases from Extremophiles. Glycomicrobiology 11: 313-340.

100. Frillingos, S., Linden, A., Niehaus, F., Vargas, C., Nieto, J. J., Ventosa, A., Antranikian, G., Drainas, C. (2000) Cloning and expression of α-amylase from the hyperthermophilic archaeon Pyrococcus woesei in the moderately halophilic bacterium Halomonas elongata . Journal of Appl. Microbiol. 88: 495-503.

99. Albuquerque, L., Rainey, F. A., Chung, A. P., Sunna, A., Nobre, M. F., Grote, R., Antranikian, G., da Costa, M. S. (2000) Alicyclobacillus hesperidum sp. nov. and a related genomic species from solfataric soils of Sao Miguel in the Azores. Int. J. Sys. Evol. Microbiol. 50: 451-457.

98. Kähler, M., Antranikian, G. (2000). Cloning and characterization of a family B DNA polymerase from the hyperthermophilic crenarchaeon Pyrobaculum islandicum . J. Bacteriol. 182 (3): 655-663.


97. Schwerdtfeger, R. M., Chiaraluce, R., Consalvi, V., Scandurra, R., Antranikian, G. (1999) Stability, refolding and Ca2+ binding of pullulanase from the hyperthermophilic archaeon Pyrococcus woesei . Eur. J. Biochem. 264:479-487.

96. Linden, A., Niehaus, F., Antranikian, G. (20 00) Single-step purification of a recombinant thermostable α-amylase after solubilization of the enzyme from insoluble aggregates. Journal of Chromtography B. 737: 253-259.

95. Andrade, C.M., Pereira, N. Jr., Antranikian, G. (1999) Extremely thermophilic microorganisms and their polymerhydrolytic enzymes. Revista de Microbiologia 30: 287-298.

94. Stefanova, M. E., Schwerdtfeger, R., Antranikian, G., Scandurra, R. (1999) Heat-stable pullulanase from Bacillus acidopullulyticus : characterization and refolding after guanidinium chloride-induced unfolding. Extremophiles 3: 147-152.

93. Niehaus, F., Bertoldo, C., Kähler, M., Antranikian, G. (1999) Extremophiles as a source of novel enzymes for industrial application. Appl. Microbiol. Biotechnol. 51: 711-729.

92. Bertoldo, C., Duffner, F., Jorgensen, P.L., Antranikian, G. (1999) Pullulanase Type I from Fervidobacterium pennavorans Ven 5: Cloning, sequencing, and expression of the gene and biochemical characterization of the recombinant enzyme. Appl. Environ. Microbiol. 65: 2084-2091.

91. Heiden, S., C. Bock, C., Antranikian, G. (eds.) (1999). Industrielle Nutzung von Biokatalysatoren – Ein Beitrag zur Nachhaltigkeit. 15. Osnabrücker Umweltgespäche. Initiativen zum Umweltschutz, Band 14, Erich Schmidt Verlag, Berlin.

90. Grote, R., Li, L., Tamaoka, J., Kato, C., Horikoshi, K., Antranikian, G. (1999) Thermococcus siculi sp. nov., a novel hyperthermophilic archaeon isolated from a deep-sea hydrothermal vent at the Mid-Okinawa Trough. Extremophiles 3: 55-62.

89. Becker, P., Köster, D., Popov, M. M., Markossian, S., Antranikian, G., Märkl, H. (1999) The biodegradation of olive oil and the treatment of lipid-rich wool scouring wastewater under aerobic thermophilic conditions. Water Research 33:653-660.



88. Canganella, F., Jones, W. J., Gambacorta, A., Antranikian, G. (1998) Thermococcus guaymasensis sp. nov. and Thermococcus aggregans sp. nov., two novel thermophilic archaea isolated from the Guaymas Basin hydrothermal vent site. Intern. Journal of System. Bacteriol. 48: 1181-1185.

87. Antranikian, G. (Vol. ed.) (1998). Biotechnology of extremophiles. Advances in Biochem. Eng./Biotechnol. 61, Springer-Verlag, Berlin.

86. Ladenstein, R., Antranikian, G. (1998) Proteins from hyperthermophiles: Stability and enzymatic catalysis close to the boiling point of water. Advances in Biochem. Eng./Biotechnol. 61: 37-85.

85. Müller, R., Antranikian, G., Maloney, S., Sharp, R. (1998) Thermophilic degradation of environmental pollutants. Advances in Biochem. Eng./Biotechnol. 61: 155-169.

84. Antranikian, G. (1998) Microbiology. McGraw-Hill Yearbook of Science & Technology, 249-251.

83. Moracci, M., Di Lernia, I., Antranikian, G., De Rosa, M., Rossi, M. (1998) Thermozymes in carbohydrate processing. VTT Symposium 177. VTT Biotechnology and Food Research. UDC 664:663.1:579.67. 56-65.



82. Niehaus, F., Frey, B., Antranikian, G. (1997) Cloning and characterisation of a thermostable α-DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. TY. GENE 204: 153-158.

81. Chiaraluce, R., Schwerdtfeger, R., Scandurra, R., Antranikian, G., Consalvi, V. (1997) Acid-induced disassembly of glutamate dehydrogenase from the hyperthermophilic archaeon Pyrococcus furiosus occurs below pH 2.0. Eur. J. Biochem. 247: 224-230.

80. Antranikian, G., Grote, R. (1997). Die biotechnologische Bedeutung extremophiler Mikroorganismen und ihrer Enzyme. Schriftenreihe “Nachwachsende Rohstoffe”, Band 10, 25-31, Landwirtschaftsverlag, Münster.

79. Kozianowski, G., Canganella, F., Rainey, F. A., Hippe, H., Antranikian, G. (1997) Purification and characterization of thermostable pectate-lyases from a newly isolated thermophilic bacterium, Thermoanaerobacter italicussp. nov. Extremophiles 1: 171-182.

78. Becker, P., Abu-Reesh, I., Markossian, S., Antranikian G., Märkl, H., (1997) Determination of the kinetic parameters during continuous cultivation of the lipase-producing thermophile Bacillus sp. IHI-91 on olive oil. Appl. Microbiol. Biotechnol. 48: 184-190.

77. Jørgensen, S., Vorgias, C. E., Antranikian, G. (1997) Cloning, sequencing, characterization, and expression of an extracellular α-Amylase from the hyperthermophilic archaeon Pyrococcus furiosus in Escherichia coli andBacillus subtilis . Biol. Chem. 272 (26): 16335-16342.

76. Canganella, F., Jones, J., Gambacorta, A., Antranikian, G. (1997) Biochemical and phylogenetic characterization of two novel deep-sea Thermococcus isolates with potential biotechnological applications. Arch. Microbiol. 167: 233-238.

75. Koch, R., Canganella, F., Hippe, H., Jahnke, K. D., Antranikian, G. (1997) Purification and properties of a thermostable pullulanase from a newly isolated thermophilic anaerobic bacterium, Fervidobacterium pennavoransVen 5. Appl. Environ. Microbiol. 63: 1088-1094.

74. Sunna, A., Puls, J., Antranikian, G. (1996). Purification and characterization of two thermostable endo-1,4-ß-D-xylanases from Thermotoga thermarum . Biotechnol. Appl. Biochem. 24: 177-185.

73. Sunna, A., Tokjian, S., Burghardt, J., Rainey, F., Antranikian, G., Hashwa, F. (1997) Identification of Bacillus kaustophilus, Bacillus thermocatennulatus and Bacillus strain HSR as members of Bacillus thermoleovorans . System. Appl. Microbiol. 20: 232-237.

72. Sunna, A., Moracci, M., Rossi, M., Antranikian, G. (1997) Glycosyl hydrolases from hyperthermophiles. Extremophiles 1: 2-13.

71. Sunna, A., Prowe, S. G., Stoffregen, T., Puls, J., Antranikian, G. (1997) Characterization of xylanases from the new isolated thermophilic xylan-degrading Bacillus thermoleovorans strain K-3d and Bacillus flavothermusstrain LB3A. FEMS Microbiol. Lett. 148: 209-216.

70. Sunna, A., Antranikian, G. (1997) Xylanolytic enzymes from fungi and bacteria. Crit. Rev. Biotechnol. 17: 39-67.



69. Mutzel, A., Reinscheid, U. M., Antranikian, G., Müller, R. (1996) Isolation and characterization of thermophilic Bacillus strain, that degrades phenol and cresols as sole carbon source at 70°C. Appl. Microbiol. Biotechnol. 46: 593-596.

68. Prowe, S. G., van de Vossenberg, J. L. M. C., Driessen, A. J. M., Antranikian, G., Konings, W. N. (1996) Sodium-coupled energy transduction in the newly isolated thermoalkaliphilic strain LBS3. J. Bacteriol. 178: 4099-4104.

67. Sunna, A., Puls, J., Antranikian, G. (1996) Purification and characterization of two thermostable endo-1,4-ß-D-xylanases from Thermotoga thermarum . Biotechnol. Appl. Biochem. 24: 177-185.

66. Sunna, A. Antranikian, G. (1996) Growth and production of xylanolytic enzymes by the extreme thermophilic anaerobic bacterium Thermotoga thermarum . Appl. Microbiol. Biotechnol. 45: 671-676.

65. Friedrich, A., Antranikian, G. (1996) Keratin degradation by a newly isolated thermophilic anaerobic bacterium, Fervidobacterium pennavorans . Appl. Environ. Microbiol. 62: 2875-2882.

64. Sunna, A., Puls, J., Antranikian, G. (1997) Characterization of the xylanolytic enzyme system of the extreme thermophilic anaerobic bacteria Thermotoga maritima, T. neapolitana and T. thermarum . Comp. Biochem. Physiol. 118: 453-461.

63. Antranikian, G., Konings, W. N., de Vos, W. M. (eds.) (1996). First International Congress on Extremophiles. FEMS Microbiol. Rev., Special Issue, 18: 89-288, Elsevier, Amsterdam.

62. Krahe, M., Antranikian, G., Märkl, H. (1996) Fermentation of extremophilic microorganisms. FEMS Microbiol. Rev. 18: 271-285.



61. Knapp, S., Karshikoff, A., Waldkötter, K., Rüdiger, A., Antranikian, G., Ladenstein, R. (1995) Preliminary crystallographic analysis of an extremely thermostable glutamate dehydrogenase from the Archaeon Pyrococcus woesei . Acta Cryst. D51: 395-398.

60. Knapp, S., Rüdiger, A., Antranikian, G., Jørgensen, P. L., Ladenstein, R. (1995) Crystallization and preliminary crystallographic analysis of an amylopullulanase from the hyperthermophilic Archaeon Pyrococcus woesei . PROTEINS: Structure, Function, and Genetics 23: 595-597.

59. Klingeberg, M., Galunsky, B., Sjøholm, C., Kasche, V., Antranikian, G. (1995) Purification and properties of a highly thermostable, sodium dodecyl sulfate-resistant and stereospecific proteinase from the extremely thermophilic archaeon Thermococcus stetteri . Appl. Environ. Microbiol. 61: 3098-3104.

58. Antranikian, G., Rüdiger, A., Canganella, F., Klingeberg, M., Sunna, A. (1995) Biodegradation of polymers at temperatures up to 130°C. J. M. S. Pure Appl. Chem. A32: 661-669.

57. Rüdiger, A., Jørgensen, P. L., Antranikian, G. (1995) Isolation and characterization of a heat-stable pullulanase from the hyperthermophilic archaeon Pyrococcus woesei after gene cloning and expression of its gene inEscherichia coli . Appl. Environ. Microbiol. 61: 567-575.

56. Leuschner, C., Antranikian, G. (1995) Heat-stable enzymes from extremely thermophilic and hyperthermophilic microorganisms. World journal of Microbiology and Biotechnology 11: 95-114.

55. Rüdiger, A., Sunna, A., Antranikian, G. (1995) Natural polysaccharides degrading enzymes, 316-340. In: Enzyme Catalysis in Organic Synthesis, vol. I., K. Drauz and H. Waldmann (eds.) vol. I. VCH, Weinheim.

54. Canganella, F., Andrade, C.M., Antranikian, G. (1994) Characterization of amylolytic and pullulytic enzymes from thermophilic archaea and from a new Fervidobacterium species. Appl. Microbiol. Biotechnol. 42: 239-245.

53. Antranikian, G. (1995) Enzymes from extreme thermophilic and hyperthermophilic Archaea and Bacteria. Handbook of Enzyme Catalysis in Organic Synthesis, (ed. Drauz & Waldmann), VCH Verlagsgeselschaft mbH, Weinheim, Germany, vol. II, S. 945-961.



52. Sunna, A., Puls, J., Antranikian, G. (1993) Characterization of the xylanolytic enzyme system of the thermophilic eubacterium Thermotoga thermarum . Proceedings of the 6th European Congress on Biotechnology. Alberghino, Fontali, Sensi (eds.), Elsevier, Amsterdam, The Netherlands.

51. Burchhardt, G., Sahm, K., Matuschek, M., Müller, H., Haeckel, K., Spreinat, A., Antranikian, G., Steinborn, G., Bahl, H. (1993) Molecular analysis of the pullulanase-encoding gene of Clostridium thermosulfurogenes EM1. Proceedings of the 6th European Congress on Biotechnology. Alberghino, Fontali, Sensi (eds.), Elsevier, Amsterdam, The Netherlands.

50. Eggen, R., Geerling, A., Waldkötter, K., Antranikian, G., De Vos, W. (1993) The glutamate dehydrogenase-encoding gene of the hyperthermophilic archaeon Pyrococcus furiosus : Sequence, transcription and analysis of the deduced amino acid sequence. Gene 132: 143-148.



49. Antranikian, G. (1992) Microbial Degradation of Natural Products. Winkelmann, G. (ed.) Weinheim: VCH-Verlagsgesellschaft. pp. 27-56.

48. Spreinat, A., Antranikian, G. (1992) Analysis of the amylolytic enzyme system of Clostridium thermos ulfurogenes EM 1: Purification and synergistic action of pullulanases and maltohexose forming α-amylase. Starch/ Stärke 44, 305-312.

47. Antranikian, G., Koch, R. (1992) Isolierung eines hitzestabilen Entzweigungsenzyms (Pullulanase) mit industrieller Relevanz aus einem neuen Fervidobacterium . VCH/Chemie Ingenieur Technik. 64: 548-550.

46. Rüdiger, A., Ogbonna, J., Märkl, H., Antranikian, G. (1992) Effect of gassing, agitation, substrate supplementation and dialysis on the growth of an extremely thermophilic archaeon Pyrococcus woesei . Appl. Microbiol. Biotechnol. 37: 501-504.



45. Freitag, R., Fenge, C., Scheper, T., Schügerl, K., Spreinat A., Antranikian, G., Fraune, E. (1991) Immunological on-line detection of specific proteins during fermentation processes. Anal. Chim. Acta 249: 113-122.

44. Specka, U., Mayer, F., Antranikian, G. (1991) Purification and properties of a thermoactive glucoamylase from Clostridium thermosaccharolyticum . Appl. Environ. Microbiol. 57: 2317-2323.

43. Freitag, R., Scheper, T., Spreinat, A., Antranikian, G. (1991) On-line monitoring of pullulanase during continuous culture of Clostridium thermosulfurogenes . Appl. Microbiol. Biotechnol. 35: 471-476.

42. Koch, R., Spreinat, A., Lemke, K., Antranikian, G. (1991) Purification and properties of a hyperther moactive α-amylase from the archaeobacterium Pyrococcus woesei . Arch. Microbiol. 155: 572-578.

41. Bahl, H., Burchhardt, G., Spreinat, A., Haeckel, K., Wienecke, A., Schmidt, B., Antranikian, G. (1991) α-Amylase of Clostridium thermosulfurogenes EM1: nucleotide sequence of the gene, processing of the enzyme, and comparison to other α-amylases. Appl. Environ. Microbiol. 57: 1554-1559.

40. Specka, U., Spreinat, A., Antranikian, G., Mayer, F. (1991) Immunocytochemical identification and localization of active and inactive α-amylase and pullulanase in cells of Clostridium thermosulfurogenes EM1. Appl. Environ. Microbiol. 57: 1062-1069.

39. Klingeberg, M., Hashwa, F., Antranikian, G. (1991) Properties of extremely thermostable proteases from anaerobic hyperthermophilic bacteria. Appl. Microbiol. Biotechnol. 34: 715-719.



38. Hundeck, H. G., Sauerbrei, A., Hübner, U., Scheper, T., Schügerl, K., Koch, R., Antranikian, G. (1990) Four-channel enzyme thermistor system for process monitoring and control in biotechnology. Anal. Chem. Acta 238: 211-221.

37. Antranikian, G. (1990) Physiology and enzymology of thermophilic bacteria degrading starch. FEMS Microbiol. Rev. 75: 201-218.

36. Antranikian, G. (1990) Starch hydrolyzing enzymes from thermophilic anaerobic bacteria: properties and biotechnological significance. Forum Mikrobiologie. 9, 399-409.

35. Antranikian, G. (1990) The biotechnological significance of thermophilic bacteria. Proceedings International Symposium on advanced Technology. Osaka-Japan, pp. 55-61.

34. Koch, R., Zablowski, P., Spreinat, A., Antranikian G. (1990) Extremely thermostable amylolytic enzyme from the archaebacterium Pyrococcus furiosus . FEMS Microbiol. Lett. 71: 21-26.

33. Koch, R., Antranikian, G. (1990) The action of amylolytic and pullulytic enzymes from various anaerobic thermophiles on linear and branched glucose polymers. Starch/Stärke 42: 397-403.

32. Freitag, R., Spreinat, A., Antranikian, G., Scheper, T. (1990) On-line immunoassay for process analysis. 5th European Congress on Biotechnology, Copenhagen, Denmark. Proceedings, vol. 2: 1025-1031.

31. Antranikian, G., Koch, R., Spreinat, A., Lemke, K. (1990) Hyperthermoactive amylases from the archaebacteria Pyrococcus woesei and Pyrococcus furiosus . 5th European Congress on Biotechnology, Copenhagen, Denmark. Proceedings, vol. 1: 596-599.

30. Spreinat, A., Antranikian, G. (1990) Purification and properties of a thermostable pullulanase from Clostridium thermosulfurogenes EM1 which hydrolyzes both α-1,6 and α-1,4-glycosidic linkages. Appl. Microbiol. Biotechnol. 33, 511-518.

29. Klingeberg, M., Vorlop, K.D., Antranikian, G. (1990) Immobilization of anaerobic thermophilic bacteria for the production of cell-free thermostable α-amylases and pullulanases. Appl. Microbiol. Biotechnol. 33: 494-500.

28. Klingeberg, M., Hippe, H., Antranikian, G. (1990) Production of novel pullulanases at high concentrations by two newly isolated thermophilic clostridia. FEMS Microbiol. Lett. 69: 145-152.



27. Klingeberg, M., Spreinat, A., Antranikian, G., Wilke, B., Vorlop, K. D., Freitag, R., Müller, W., Scheper, Th. (1989) Process development for the production of starch-degrading thermostable enzymes by immobilized cells. Dechema Biotechnol. Conf. 3: 687-690.

26. Freitag, R., Spreinat, A., Antranikian, G., Scheper, Th., Schügerl, K. (1989) Immunoassay in process analysis. Dechema Biotechnol. Conf. 3: 731-734.

25. Antranikian, G. (1989) Phosphorylation of citrate lyase ligase in Clostridium sphenoides and regulation of citrate metabolism in anaerobic bacteria. Biochem. 71: 1029-1037.

24. Madi, E., Antranikian, G. (1989) Identification and characterization of an anaerobic thermophile producing starch hydrolyzing enzymes. Appl. Microbiol. Biotechnol. 30: 422-425.

23. Antranikian, G. (1989) The formation of extracellular thermoactive amylase and pullulanase in batch culture by Thermoanaerobacter finnii . Appl. Biochem. Biotechnol. 20/21: 267-279.

22. Köhler, E., Antranikian, G. (1989) Covalent modification of proteins in Bacillus subtilis during the process of sporulation and germination. FEMS Lett. 57: 87-92.



21. Rüdiger, A., Quentmeier, A., Antranikian, G. (1988) Phosphorylation of proteins in Escherichia coli by ATP-dependent kinases. Biochem. Life Sci. Adv. 7: 213-218.



20. Koch, R., Zablowski, P., Antranikian, G. (1987) Highly active and thermostable amylases and pullulanases from various anaerobes. Appl. Microbiol. Biotechnol. 27: 192-198.

19. Antranikian, G., Zablowski, P., Gottschalk, G. (1987) Conditions for the overproduction and excretion of thermostable α-amylase and pullulanase from Clostridium thermohydrosulfuricum . Appl. Micobiol. Biotechnol. 27: 75-81.

18. Antranikian, G., Herzberg, C., Mayer, F., Gottschalk, G. (1987) Changes in cell-envelope structure of Clostridium strain EM1 during massive production of α-amylase and pullulanase. FEMS Lett. 41: 193-197.

17. Antranikian, G., Herzberg, C., Gottschalk, G. (1987) Production of thermostable α-amylase, pullulanase and α-glucosidase in continuous culture by a new Clostridium isolate. Appl. Environ. Microbiol. 53: 1668-1673.

16. Madi, E., Antranikian, G., Ohmiya, K., Gottschalk, G. (1987) Thermostable amylolytic enzymes from a new Clostridium isolate. Appl. Environ. Microbiol. 53: 1661-1667.

15. Antranikian, G., Giffhorn, F. (1987) Citrate metabolism in anaerobic bacteria. FEMS Microbiol. Rev. 46: 175-198.

14. Quentmeier, A., Holzenburg, A., Mayer, F., Antranikian, G. (1987) Reevaluation of citrate lyase from Escherichia coli . Biochim. Biophys. Acta. 913: 60-65.

13. Antranikian, G., Gottschalk, G. (1987) Production of thermostable enzymes for starch hydrolysis. 4th European Congress on Biotechnology. Amsterdam, The Netherlands, pp. 261-264.



12. Herzberg, C., Antranikian, G. (1986) Evidence for a unique pattern of citrate lyase inactivation in Clostridium sphenoides . Biochim. Biophys. Acta. 871: 107- 120.

11. Quentmeier, A., Antranikian, G. (1986) Covalent modification of proteins in Escherichia coli growing anaerobically with nitrate as electron acceptor. FEMS Lett. 34: 231-235.

10. Averhoff, B., Antranikian, G., Gottschalk, G. (1986) Phosphorylation and nucleotidylation of proteins in Rhodocyclus gelatinosus . FEMS Lett. 33: 299-304.



9. Antranikian, G., Herzberg, C., Gottschalk, G. (1985) Covalent modification of citrate lyase ligase from Clostridium sphenoides by phosphorylation/dephosphorylation. Eur. J. Biochem. 153: 413-420.

8. Antranikian, G., Herzberg, C., Gottschalk, G. (1985) In vivo phosphorylation of proteins in Clostridium sphenoides . FEMS Lett. 27: 135-138.

7. Quentmeier, A., Antranikian, G. (1985) Characterization of citrate lyase from Clostridium sporosphaeroides . Arch. Microbiol. 141: 85-90.



6. Antranikian, G., Friese, C., Quentmeier, A., Hippe, H., Gottschalk, G. (1984) Distribution of the ability of citrate utilization amongst clostridia. Arch. Microbiol. 138: 179-182.



5. Antranikian, G., Herzberg, C., Gottschalk, G. (1982) Characterization of ATP citrate lyase from Chlorobium limicola . J. Bacteriol. 152: 1284-1287.

4. Gottschalk, G., Giffhorn, F., Antranikian, G. (1982) The regulation of citrate lyase by acetylation/deacetylation. Biochem. Soc. Trans. 10: 324-326.

3. Antranikian, G., Klinner, C., Kümmel, A., Schwanitz, D., Zimmerman, T., Mayer, F., Gottschalk, G. (1982) Purification of L-glutamate dependent citrate lyase from Clostridium sphenoides and electron microscopic analysis of citrate lyase isolated from Rhodopseudomonas gelatinosa, Streptococcus diacetilactis , and C. sphenoides . Eur. J. Biochem. 126: 35-42.

2. Antranikian, G., Gottschalk, G. (1982) Copurification of citrate lyase and citrate lyase ligase from Rhodopseudomonas gelatinosa and subsequent separation of the two enzymes. Eur. J. Biochem. 126: 43-47.



1. Antranikian, G., Giffhorn, F., Gottschalk, G. (1978) Activation and inactivation of citrate lyase ligase from Rhodopseudomonas gelatinosa . FEBS Lett. 88: 67-70.



Dissertations completed

01. Quentmeier, Armin (1987) Untersuchungen zur kovalenten Modifikation von Proteinen und zum Citratstoffwechsel in Escherichia coli.

02. Rüdiger, Andrea (1990) Kovalente Modifikation durch Phosphorylierung von Proteinen aus Escherichia coli: Isolierung und Charakterisierung einer neuartigen Proteinkinase.

03. Spreinat, Andreas (1990) Isolierung, Charakterisierung und Synergismus der Pullulanasen und a-Amylase aus Clostridium thermosulfurogenes EM1.

04. Koch, Reinhard (1991) Isolierung und Charakterisierung einer termostabilen Pullulanase aus einem neuisolierten anaeroben Bakterium.

05. Klingeberg, Michael (1993) Reinigung und Charakterisierung einer  hitzeresistenten Serinprotease aus dem thermophilen Archaeon Thermococcus stetteri.

06. Friedrich, Andrea (1994) Keratinabbau durch ein neuisooiertes, thermophile anaerobes Bakterium, Fervidobacterium pennavorans.

07. Waldkötter, Kerstin (1995) Reinigung und Charakterisierung der extrem thermostabilen Glutamat-Dehydrogenase des hyperthermophilen Archaeon Pyrococcus spec.

08. Sunna, Anwar (1995) Production and characterization of the xylanolytic enzyme system of the extreme thermophilic bacteria belonging to the genus Thermotoga.

09. Prowe, Steffen (1996) Characterization of extracellular amylolytic enzymes and sodium coupled energy transduction of a newly isolated thermoalkaliphilic bacterium, Thermoalcalibacter bogoriae.

10. Niehaus, Frank (1996) Klonierung und Charakterisierung einer neuen, thermostabilen a-DNA Polymerase.

11. Andrade, Carolina (1996) Production and characterization of extremely thermostable xylanolytic and amylolytic enzymes from the hyperthermophilic archaeon Pyrodictium abyssi.

12. Schwerdtfeger, Ruth (1997) Structure/Function relationships of pullulanase and glutamate dehydrogenase from the hyperthermophilic archaeon Pyrococcus woesei.

13. Hebenbrock, Swantje (1998) Isolierung und Charakterisierung von thermophilen Mikroorganismen und deren Untersuchungen zum mikrobiellen Abbau von Naphthalin und Benzoesäure.

14. Linden, Anni (1999) Reinigung und biochemische Charakterisierung einer thermostabilen a-Amylase aus Pyrococcus woesei nach Klonierung und Expression in Escherichia coli und Halomonas elongata.

15. Kähler, Markus (1999) Cloning and characterization of DNA polymerases from the hyperthermophilic crenarchaeon Pyrobaculum islandicum.

16. Serour, Ehab (2000) Production, purification and characterization of novel thermoactive glucoamylases from the hyperacidophilic archaea Thermoplasma acidophilum, Picrophilus torridus and Picrophilus oshimae

17. Rießen, Sabine (2000) Isolierung und Charakterisierung von thermophilen, keratinabbauenden Mikroorganismen und Untersuchung ihrer proteolytischen Enzymsysteme.

18. Grote, Ralf (2000) Isolation and characterization of extreme and hyperthermophilic microorganisms and screening for recombinant thermostable enzymes.

19. Böhlke, Kristina (2000) Two DNA polymerases from Thermococcus aggregans: Mutational analysis of the family B polymerase and cloning of the genes for a heterodimeric enzyme.

20. Grudieva, Tatiana (2002) Isolation, identification and characterization of psychrophilic microorganisms and screening for their cold-active hydrolytic enzymes.

21. Gödde, Carolin (2002) Klonierung und Expression thermostabiler Proteasen aus Bakterien der Ordnung Thermotogales.

22. Müller, Patrick (2003) Klonierung, Expression und Charakterisierung einer thermoaktiven Nitrilase aus Pyrococcus abysii.

23. Deppe, Uta (2003) Degradation of crude oil at low temperatures by a newly isolated psychrotolerant bacterial consortium.

24. Egorova, Ksenia (2003) Screening and biochemical characterization of novel amidases from psychro-and thermophilic microorganisms.

25. Markosyan, Samson (2003) Isolierung des neuen thermophilen, Öl abbauenden Stammes Geobacillus thermoleovorans IHI-91. Klonierung, Reinigung und Charakterisierung einer Esterase und Lipase.

26. Thiemann, Volker (2005) Characterisation of the branching enzyme and the cyclodextrin glycosyltransferase from the thermoalkaliphilic bacterium anaerobranca gottschalkii.

27. Schepers, Birgit (2005) Cloning and Characterization of a novel glucoamylase from the thermoacidophilic Archaeon Picrophilus torridus.

28. Weber, Daniel (2005) Oligonucleotide microarrays fort he detection and identification of beer spoilage bacteria.

29. Borchert, Martin S. (2005) Identification, Cloning and Recombinant Expression of Novel Enzymes with Industrial Relevance from a Marine Sponge Associated Bacillus Species.

30. Dock, Christiane (2005) Hitze- und säurestabile Glucoamylasen aus Archaeen.

31. Qoura, Farah M. (2006) Isolation and characterization of new psychrophilic bacteria; cloning and characterization of industrial relevant pullulanase and serine protease.

32. Wirth, Olaf R. (2006) Screening for biofilm degrading enzymes from extremophiles.

33. Royter, Maryna (2006) Cloning and characterization of thermostable lipases from thermophilic anaerobic bacteria.

34. Al Khudary, Rami (2006) A Novel Cold Active Esterase from the Marine Psychrotolerant Isolate Pseudoalteromonas arctica sp.nov. 

35. Hess, Matthias (2007) Novel biocatalysts from the thermoacidophilic Archaeon Picrophilus torridus.

36. Katzer, Moritz (2008) Production and characterization of thermostable cellulases from metagenomic gene libraries.

37. Klippel, Barbara (2011) Charakterisierung von cellulolytischen und xylanolytischen Enzymen aus dem thermophilen anaeroben Bakterium Fervidobacterium gondwanense.

38. Bockemühl, Vera (2011) Produktion einer Endo-b-1,4-Xylanase aus Myceliophthora thermophila mittels Hochzelldichtefermentation von Pichia pastoris  und Charakterisierung des Enzyms.

39. Jabbour, Dina (2011) A Novel b-Glucosidase and a Chimeric Endoglucanase-CBM for Cellulose Hydrolysis at Elevated Temperatures.

40. Lochner, Adriane (2011) Proteomic characterization of the cellulolytic enzyme system expressed by the extremely thermophilic bacteria Caldicellulosiruptor spp.

41. Halbsguth, Tobias (2012) Flavin-abhängige Glukose-Dehydrogenasen für die Blutzuckerbestimmung

42. Königsfeld, Nele Isabelle (2013) Cloning, expression and characterization of novel thermostable plant cell wall degrading enzymes

43. Basner, Alexander (2013) Automatisiertes Hochdurchsatz-Screening nach neuartigen Biokatalysatoren: Isolierung und biochemische Charakterisierung einer Glukose-Dehydrogenase

44. Blank, Saskia (2013) Charakterisierung thermostabiler Glykosidhydrolasen zum Abbau von Lignocellulose

45. Krüger, Anna (2013) Cold-active microbial oxidoreductases from Arctic sea ice and the deep sea

46. Schröder, Carola (2013) Identification and characterization of recombinant glycoside hydrolases recovered from metagenomes for the application in biorefineries

47. Röske, Immo (2014) Mikrobiologische Charakterisierung und populationsdynamische Analysen von Biogasreaktoren zur Vergärungvon Dünnschlempe im Hochtemperaturbetrieb

48. Rizk, Mazen (2014) End-to-end gene fusions and their impact on the production of multifunctional biomass degrading enzymes

49. Burkhardt, Christin (2017) Identifizierung und Charakterisierung thermostabiler Laminarinasen zum Abbau mariner Biomasse

50. Meyer-Heydecke, Neele (2019) Stabile Amylasen für die biotechnologische Anwendung - Screening und Charakterisierung

51. Busch, Philip (2019) Anwendung einer kombinierten Analyse aus Metagenomik und Metatranskriptomik zur Identifizierung von thermophilen biotechnologisch-relevanten Enzymen

52. Suleiman, Marcel (2019) Microbial diversity of shallow marine hydrothermal vents of Vulcano Island and characterization of an extremely heat-active endoglucanase