Dr. rer nat Christian Schäfers

 

Research topics

 

  • Bioinformatics and computational biology
  • Development and establishment of computational analyses for (meta)-omics
  • Maintenance of NGS data pipelines (2nd and 3rd generation sequencing technologies)
  • Genomics (assembly and annotation)
  • Metagenomics (binning and annotation)
  • Bio-based products 
  • Screening for novel producers & bio-based products
  • Strain improvement for industrial application
  • High Throughput Screening for biomass-degrading enzymes
  • Biochemical characterization of enzymes

 

Publications

 

2018

Krüger A, Schäfers C, Schröder C, and Antranikian G (2018) Towards a sustainable biobased industry - Highlighting the impact of extremophiles, New Biotechnology; Volume 40, Part A, pp.144-153: doi: doi.org/10.1016/j.nbt.2017.05.002

2017

Antranikian G, Suleiman M, Schäfers C, Adams MWW, Bartolucci S, Blamey JM, Birkeland NK, Bonch-Osmolovskaya E, da Costa MS, Cowan D, Danson M, Forterre P, Kelly R, Ishino Y, Littlechild J, Moracci M, Noll K, Oshima T, Robb F, Rossi M, Santos H, Schönheit P, Sterner R, Thauer R, Thomm M, Wiegel J, and Stetter, KO (2017) Diversity of bacteria and archaea from two shallow marine hydrothermal vents from Vulcano Island, Extremophiles.

Schäfers C, Blank S, Wiebusch S, Elleuche S, and Antranikian G. (2017) Complete genome sequence of Thermus brockianus GE-1 reveals key enzymes of xylan/xylose metabolism. Standards in Genomic Sciences 12, 22.

2016

Elleuche S, Esselun P, Grote R, Klippel B, Krüger A, Liese A, Ostrop M, Schäfers C, Schröder C, Antranikian G (2016) Meeting report: 8th International Congress on Biocatalysis (Biocat2016), Hamburg, Germany, 28 August-1 September, 2016. Catalysts 6, 160; doi:10.3390/catal6100160

2015

Schäfers C, Elleuche S, Antranikian G (2015) Biochemical Properties and Applications of Heat-active Biocatalysts. In: Li F-L (Ed.), Thermophilic Microorganisms. Caister Academic Press; pp. 47-90

Elleuche S, Schäfers C, Blank S, Schröder C, Antranikian G. (2015) Exploration of extremophiles for high temperature biotechnological processes. Curr. Opin. Microbiol. 25C:113-119

2010

Elleuche S, Bernhards Y, Schäfers C, Varghese JM, Nolting N, Pöggeler S (2010) The small serine‐threonine protein SIP2 interacts with STE12 and is involved in ascospore germination in Sordaria macrospora. Eur J Cell Biol 89:873‐887

 

Curriculum vitae

 

2012 Project leader and lecturer at the Institute of Technical Microbiology, Hamburg University of Technology, Hamburg, Germany
2011

PostDoc at the Department of General and Molecular Botany, Ruhr University Bochum, Bochum, Germany

2011

PhD thesis (Prof. Dr. Ulrich Kück), Title: Heterotrimere G-Proteine in Pilzen: Die Funktion der Gα‐subunit GSA1 in der Entwicklung des Modellorganismus Sordaria macrospora, Ruhr-University Bochum, Bochum, Germany

2007

Diploma thesis (Prof. Dr. Stefanie Pöggeler), Title: Funktionelle Analyse von Interaktionspartnern des Transkriptionsfaktors Ste12 aus Sordaria macrospora, Ruhr University Bochum, Bochum, Germany (externally at the Department of Genetics of Eukaryotic Microorganisms, Georg‐August University, Göttingen, Germany)

2002  2007 Diploma program (Molecular biology and Genetics), Ruhr University Bochum, Bochum, Germany
1978 Born in Witten, Germany

 

Ad hoc Reviewer

 

Biomass Conversion and Biorefinery, Extremophiles, Standards in Genomic Sciences

 

Posters and oral presentations

 

24. Schäfers C, Busch P, Suleiman M, Burkhardt C, *Antranikian G (2018) Analysis of extreme thermophilic communities and their enzymes applying integrative multi-omic approach. In: 12th International Congress of Extremophiles, Ischia, Italy (oral presentation)

23. *Meyer-Heydecke N, *Krüger A,  Schäfers C, Peters A, Antranikian G (2018) Identification of novel ᴅ-carbamoylases for the production of optically pure amino acids. In: 9th International Congress on Biocatalysis, Hamburg, Germany, eBook of Abstracts, p. 81

22. *Suleiman M, Klippel B, Busch P, Schäfers C, Antranikian G (2018) Influence of recalcitrant substrates on microbial diversity of samples from Azorean hot springs. In: 9th International Congress on Biocatalysis, Hamburg, Germany, eBook of Abstracts, p. 28

21. *Busch P, Suleiman M, Schäfers C, Antranikian G (2018) New strategy for the discovery of carbohydrate-active enzymes through integrated 'omics. In: 9th International Congress on Biocatalysis, Hamburg, Germany, eBook of Abstracts, p. 27

20. *Busch P, Suleiman M, Schäfers C, Antranikian G (2018) Analysis of a thermophilic anaerobic microbial community and its potential for plant biomass degradation by using omic technologies. In: Tagungsband zur VAAM-Jahrestagung 2018, Wolfsburg, p. 195 (oral presentation)

19. *Suleiman M, Klippel B, Busch P, Schäfers C, Antranikian G (2018) The influence of complex substrates on microbial diversity from four Azorean hot springs. In: Tagungsband zur VAAM-Jahrestagung 2018, Wolfsburg, p. 144

18. *Busch P, Schäfers C, Antranikian G (2017) Discovery of novel enzymes for biotechnological applications by multi-omic approach. In: 5.Workshop des FSP “Integrierte Biotechnologie und Prozesstechnik“, Hamburg, Germany (oral presentation)

17. *Schäfers C, Blank S, Wiebusch S, Elleuche S, Antranikian G (2017) Complete Genome sequence of thermophilic xylan-degrading strain Thermus brockianus GE-1. In: Tagungsband zur VAAM-Jahrestagung 2017, Würzburg, p. 202

16. *Suleiman M, Schäfers C, Stetter K.O., Antranikian G (2017) Community composition of Bacteria and Archaea from hot marine hydrothermal vents of Vulcano Island.In: Tagungsband zur VAAM-Jahrestagung 2017, Würzburg, p. 108

15. *Schäfers C, Blank S, Wiebusch S, Elleuche S, Antranikian G (2016) Whole Genome Sequencing of Thermophilic Xylan-degrading Strain Thermus brockianus GE-1. In: 8th International Congress on Biocatalysis, Hamburg, Germany, eBook of Abstracts (oral presentation)

14. *Burkhardt C, Meyer N, Schäfers C, Wiebusch S, Schirrmacher G, Reisinger C, Antranikian G (2016) Enzymatic hydrolysis of macroalgae for the production of biobased chemicals
. In: Tagungsband zur VAAM-Jahrestagung 2016, Jena, p. 71

13. *Schäfers C, Burkhardt C, Meyer N, Wiebusch S, Schirrmacher G, Reisinger C, Antranikian G (2015) Macroalgae as a resource for biobased industry. In: 16th International Conference Rural-Urban Symbiosis (RAMIRAN2015), Hamburg, Germany, Book of Abstract, p. 9 (oral presentation)

12. *Schäfers C, Burkhardt C, Meyer N, Wiebusch S, Schirrmacher G, Reisinger C, Antranikian G (2015) LIPOMAR - Microalgae as a promising feedstock for high-valuable chemicals, In: Tagungsband zur VAAM-Jahrestagung 2015, Marburg, p. 66 (oral presentation)

11. *Burkhardt C, Schäfers C, Antranikian G (2014) Thermostable laminarinases as promising biocatalysts for the production of biofuels and chemicals. In: Tagungsband zur VAAM-Jahrestagung 2014, Dresden, p. 173

10. *Meyer N, Schäfers C, Antranikian G (2014) A cold-active alginate lyase from deep-sea sediment metagenome for degradation of marine biomass. In: Tagungsband zur VAAM-Jahrestagung 2014, Dresden, p. 179

9. *Meyer N, Schäfers C, Antranikian G (2014) Identification of a cold-active alginate lyase from deep-sea sediment metagenome. In: 7th International Congress on Biocatalysis, Hamburg, Germany, Book of Abstracts, p. 84

8. *Burkhardt C, Schäfers C, Antranikian G (2014) Hydrolyzing macroalgae with thermostable laminarinases for the production of biofuels and chemicals . In: 7th International Congress on Biocatalysis, Hamburg, Germany, Book of Abstracts, p. 85

7. *Schäfers C, Burkhardt C, Meyer N, Schirrmacher G, Reisinger C, Antranikian G (2014) LIPOMAR - Macroalgae as a promising feedstock for the production of high value chemicals. In: 3.Workshop des FSP „Integrierte Biotechnologie und Prozesstechnik", Hamburg, Germany (oral presentation)

6. *Kück U, Nowrousian M, Teichert I, Bloemendal S, Schäfers C, Dirschnabel D, Nordzieke S (2011) Sordaria macrospora, a fungal genetic model system to investigate fruiting body development. In: XIII International Congress of Mycology, Sapporo, Japan

5. *Pöggeler S, Elleuche S, Bernhards Y, Schäfers C, Varghese JM, Nolting N (2010) The novel 9.5‐kDa protein SIP2 specifically interacts with STE12 in Sordaria macrospora. In: 10th European Conference on Fungal Genetics, Noordwijkerhout, Netherlands 

4 . *Schäfers C, Kück U (2010) Activation state‐dependent interaction partners of the G protein alpha subunit GSA1 in Sordaria macrospora. In: 9th International Mycological Congress, Edinburgh, UK

3 . *Schäfers C, Kück U (2009) Heterotrimeric G protein in Sordaria macrospora: Interaction partners of the G protein alpha subunit GSA1. In: 9th VAAM Symposium "Molecular Biology of Fungi", Münster, Germany (oral presentation)

2 . *Schäfers C, Kück U (2009) G‐Protein mediated signal transduction in a filamentous fungus: Use of the yeast‐two‐hybrid‐system to identify interaction partners of the alpha subunit GSA1. In: VAAM annual meeting, Bochum, Germany 

1.  Kamerewerd J, *Schäfers C, Jansson M, Nowrousian M, Pöggeler S, Kück U (2009) Distinct roles of three G protein α‐subunits and an adenylyl cyclase in fruiting body development of the homothallic fungus Sordaria macrospora. In: 25th Fungal Genetics Conference, Asilomar, Pacific Grove, USA