Dr. rer. nat. Anna Krüger

 

 

Research topics and industrial cooperation

 

  • Enzymatic oxidation systems for food and technical applications
  • High-throughput screening of extremophilic microorganisms for oxidative enzymes
  • Fermentation strategies with E. coli, B. subtilis or P. pastoris as expression hosts for the production of oxidative enzymes
  • Synthetic biology as means for enzyme optimization
  • Production of enzyme congeners by incorporation of non-canonical amino acids
  • High-throughput characterization of extremozymes and enzyme congeners

 

Publications

 

2018

Krüger A., Schäfers C., Schröder C., Antranikian G. (2018) Towards a sustainable biobased industry – Highlighting the impact of extremophiles, New Biotechnology; Volume 40, Part A, pp. 144-153; doi: doi.org/10.1016/j.nbt.2017.05.002

2016

Elleuche S, Esselun P, Grote R, Klippel B, Krüger A, Liese A, Ostrop M, Schäfers C, Schröder C, Antranikian G (2016) 8th International Congress on Biocatalysis (Biocat2016), Hamburg, Germany, 28 August–1 September, 2016 (Meeting Report). Catalysts 2016, 6, 160; doi:10.3390/catal6100160

Krüger A, Elleuche S, Sahm K, Antranikian G (2016) Robust biocatalysts - routes to new diversity. In: Hilterhaus L, Liese A, Kettling U, Antranikian G (Eds.) Applied Biocatalysis: From Fundamental Science to Industrial Applications. Wiley-VCH Verlag GmbH; pp. 31-51

2008 

Rotthues A, Kappler J, Lichtfuß A, Kloos, DU, Stahl, DJ, Hehl, R (2008) Post-harvest regulated gene expression and splicing efficiency in storage roots of sugar beet (Beta vulgaris L.). Planta 227, 1321-1332

 

Curriculum vitae

 

2016- Senior Scientific Officer at the Institute of Technical Microbiology, Hamburg University of Technology, Hamburg, Germany
2011-2016 Project leader and lecturer at the Institute of Technical Microbiology, Hamburg University of Technology, Hamburg, Germany
2007-2011 Doctoral thesis at the Institute of Technical Microbiology, Hamburg University of Technology, Hamburg, Germany. Title: “Cold-active microbial oxidoreductases from Arctic sea ice and the deep sea”
2007

Diploma thesis at the Department of Plant Sciences, University of Cambridge, Cambridge, UK. Title: “Tetrapyrrole synthesis and the regulation of nuclear gene expression”

2005

Student research project at the Department of Plant Sciences, University of Cambridge, Cambridge, UK. Title: “Analysis of the tetrapyrrole pathway in Arabidopsis thaliana

2002-2007 Studies in biotechnology at Carolo-Wilhelmina Technical University of Braunschweig, Braunschweig, Germany
1983 Born in Hannover, Germany

 

Memberships

 

2008- VAAM – Vereinigung für Allgemeine und Angewandte Mikrobiologie
2009-2017btS – Biotechnologische Studenteninitiative e.V.
2014-2015ISE – International Society for Extremophiles

 

Posters and oral presentations

 

15. *Meyer-Heydecke N, Krüger A, Peters A, Antranikian G (2018). A novel α-amylase with remarkable characteristics for biotechnological applications. In: Tagungsband zur VAAM-Jahrestagung 2018, Wolfsburg, Germany, p. 67

14. *Krüger A, Piascheck H, Nölle V, Odenthal U, Villain L, Beutel S, Scheper T, Antranikian G (2017). Innovative downstream processing techniques for the production of recombinant cytokines based on membrane adsorbers. In: Tagungsband zur 5. Gemeinsamen Konferenz von DGHM und VAAM, Würzburg, Germany, p. 336

13. *Krüger A, Welsch N, Piascheck H, Beyer S, Kabisch J, Popper L, Antranikian G, Schweder T (2016). Production of sulfhydryl oxidase from Saccharomyces cerevisiae with Bacillus subtilis expression strains. In: 8th International Congress on Biocatalysis, biocat2016, eBook of Abstracts, Ed: Antranikian G. TuTech Innovation GmbH, TuTech Verlag, Hamburg. ISBN: 978-3-946094-07-4

12. *Meyer N, Krüger A, Peters A, Antranikian G (2016). Activity-based screening for the identification of novel α-amylases for industrial processes and daily applications. In: 8th International Congress on Biocatalysis, biocat2016, eBook of Abstracts, Ed: Antranikian G. TuTech Innovation GmbH, TuTech Verlag, Hamburg. ISBN: 978-3-946094-07-4

11. *Krüger A, Hoesl MG, Peters A, Budisa N, Antranikian G (2014). Synthetic biology as means for enzyme optimization: improving Thermoanaerobacter tengcongensis esterase by incorporation of non-canonical amino acids. In: Tagungsband zur 4. Gemeinsamen Konferenz von DGHM und VAAM, Dresden, Germany, p. 82 (oral presentation)

10. *Krüger A, Antranikian G (2014). Cold-active microbial oxidoreductases from Arctic sea ice and the deep sea. In: 10th International Congress on Extremophiles, St. Petersburg, Russia, Book of Abstracts, p. 287

9. *Krüger A, Hoesl MG, Peters A, Budisa N, Antranikian G (2014). Improving industrially relevant enzymes by incorporation of non-canonical amino acids. In: 7th International Congress on Biocatalysis, Hamburg, Germany, Book of Abstracts, p. 140

8. *Chatziefthimiou SD, Pinotsis N, Krüger A, Marrakchi H, Royter M, Daffe M, Antranikian G, Wilmanns M (2014). The structure of a thermoactive lipase from Thermoanaerobacter thermohydrosulfuricus: snapshots of the lipase mechanism. In: 7th International Congress on Biocatalysis, Hamburg, Germany, Book of Abstracts, p. 106 (oral presentation)

7. *Krüger A, Hoesl MG, Chatziefthimiou SD, Wilmanns M, Budisa N, Antranikian G (2013). P29 Lipase congeners with improved catalytic activity and substrate access. In: BIOKATALYSE2021 Clusterkonferenz 2013, Hamburg, Germany

6. *Krüger A, Klippel B, Antranikian G (2013). PZ: Zentrales Technologie- und Serviceprojekt für Screening, Fermentation und Proteinreinigung. In: BIOKATALYSE2021 Clusterkonferenz 2013, Hamburg, Germany

5. *Krüger A, Antranikian G (2012). Characterization of cold-active α-glycerophosphate oxidase from Carnobacterium sp. 33-1. In: 6th International Congress on Biocatalysis, Hamburg, Germany, Book of Abstracts, p. 133

4. *Boysen H, Krüger A, Piascheck H, Halbsguth T, Antranikian G (2012). Produktion einer Sulfhydryl-Oxidase mit Bacillus subtilis. In: Tagungsband zur 9. Hamburger Studententagung „Innovative Medizin- und Biotechnologie aus Hamburg", Hamburg, Germany, p. 38

3. *Hoesl MG, Krüger A, Winkelmann N, Elleuche S, Wiltschi B, Antranikian G, Budisa N (2012). Enhancing industrially relevant enzymes with an expanded genetic code. In: European Federation of Biotechnology, 1st Congress on Applied Synthetic Biology in Europe 2012, Barcelona, Spain

2. *Krüger A, Antranikian G (2011). Oxidoreductases from extremophilic microorganisms isolated from Spitsbergen and the deep sea. In: Tagungsband zur VAAM-Jahrestagung 2011, Karlsruhe, Germany, p. 168

1. *Lichtfuß A, Antranikian G (2009). Glycerol degradation by psychrophilic bacteria. In: Tagungsband zur VAAM-Jahrestagung 2009, Bochum, Germany, p. 200